A5004896566- Nanoplatforms for cancer theranostics
- Chemokine receptors and signaling
- Advanced Biosensing Techniques and Applications
- Histone Deacetylase Inhibitors Research
- Calcium signaling and nucleotide metabolism
- Lymphatic System and Diseases
- Angiogenesis and VEGF in Cancer
- Cancer Immunotherapy and Biomarkers
- Breast Cancer Treatment Studies
- Photodynamic Therapy Research Studies
- Parkinson's Disease Mechanisms and Treatments
- Medical Imaging Techniques and Applications
- Neurological diseases and metabolism
- Genetic Neurodegenerative Diseases
- Cancer, Stress, Anesthesia, and Immune Response
- Autophagy in Disease and Therapy
- Cancer Cells and Metastasis
Xiamen University
2023-2024
Shantou University
2019
Cancer Hospital of Shantou University Medical College
2019
Sichuan University
2017
West China Hospital of Sichuan University
2017
Intraoperative surgical margin assessment remains a challenge during breast-conserving surgery. Here, we report combined strategy of immuno–positron emission tomography (PET) for preoperative detection breast cancer and guided margins in surgery through second near-infrared (NIR-II) fluorescence imaging trophoblastic cell surface antigen 2 (TROP2). We demonstrated that the intensity PET signals tumors was nearly five times higher than normal tissue with zirconium-89 tracer conjugated to...
Background It has been noticed that the patients with multiple system atrophy (MSA) can accompany depression and anxiety. This study aimed to establish incidence determinants of anxiety symptoms in Chinese MSA patients. Methods A total 237 were enrolled study. Neuropsychological assessment was performed using Hamilton Depression Rating Scale-24 items Anxiety Scale. Results We found 62.0% 71.7% had at least mild symptoms, respectively. The severity associated lower educational years (P=.024),...
Sentinel lymph node (SLN) biopsy plays a critical role in axillary staging of breast cancer. However, traditional SLN mapping does not accurately discern the presence or absence metastatic disease. Detection metastasis largely hinges on examination frozen sections paraffin-embedded tissues post-SLN biopsy. To improve detection metastasis, we developed second near-infrared (NIR-II) vivo fluorescence imaging system, pairing erbium-based rare-earth nanoparticles (ErNP) with bright...
Background: Durable responses to immune-checkpoint blocking therapy (ICT) targeting programmed cell death protein-1/ligand-1 (PD-1/PD-L1) have improved outcomes for patients with triple negative breast cancer (TNBC). Unfortunately, only 19– 23% of benefit from ICT. Hence, non-invasive strategies evaluating and selecting who will ICT are critical issues TNBC immunotherapy. Methods: We developed a novel nanoparticle-Atezolizumab (NPs-Ate) consisting indocyanine green (ICG),...
<p>All Supplementary Data</p>
<div>Abstract<p>Sentinel lymph node (SLN) biopsy plays a critical role in axillary staging of breast cancer. However, traditional SLN mapping does not accurately discern the presence or absence metastatic disease. Detection metastasis largely hinges on examination frozen sections paraffin-embedded tissues post-SLN biopsy. To improve detection metastasis, we developed second near-infrared (NIR-II) vivo fluorescence imaging system, pairing erbium-based rare-earth nanoparticles...
<p>All Supplementary Data</p>
<p>All Supplementary Data</p>
<div>Abstract<p>Sentinel lymph node (SLN) biopsy plays a critical role in axillary staging of breast cancer. However, traditional SLN mapping does not accurately discern the presence or absence metastatic disease. Detection metastasis largely hinges on examination frozen sections paraffin-embedded tissues post-SLN biopsy. To improve detection metastasis, we developed second near-infrared (NIR-II) vivo fluorescence imaging system, pairing erbium-based rare-earth nanoparticles...
<div>Abstract<p>Sentinel lymph node (SLN) biopsy plays a critical role in axillary staging of breast cancer. However, traditional SLN mapping does not accurately discern the presence or absence metastatic disease. Detection metastasis largely hinges on examination frozen sections paraffin-embedded tissues post-SLN biopsy. To improve detection metastasis, we developed second near-infrared (NIR-II) <i>in vivo</i> fluorescence imaging system, pairing erbium-based...
<p>All Supplementary Data</p>