- Liver Disease and Transplantation
- Nanoparticles: synthesis and applications
- Liver Disease Diagnosis and Treatment
- Cancer therapeutics and mechanisms
- Extracellular vesicles in disease
- Bone Tumor Diagnosis and Treatments
- Analytical Methods in Pharmaceuticals
- Pediatric Hepatobiliary Diseases and Treatments
- Heme Oxygenase-1 and Carbon Monoxide
- Liver physiology and pathology
- Glycosylation and Glycoproteins Research
- Phytochemistry and Bioactivity Studies
- Infant Nutrition and Health
- Viral Infections and Vectors
- Drug Transport and Resistance Mechanisms
- Alcohol Consumption and Health Effects
- Pharmacology and Nanomedicine Research
- Bacterial Infections and Vaccines
- Hepatitis Viruses Studies and Epidemiology
- Graphene and Nanomaterials Applications
- Inflammation biomarkers and pathways
- Liver Diseases and Immunity
- Dysphagia Assessment and Management
- Neurofibromatosis and Schwannoma Cases
- Protein Structure and Dynamics
Institute of Liver and Biliary Sciences
2021-2025
All India Institute of Medical Sciences
2024
Panjab University
2022-2024
Christian Medical College & Hospital
2020
Christian Medical College
2020
Public Works Department Buildings and Roads
2014
ABSTRACT Human granulocytic anaplasmosis (HGA) is an emerging, rickettsial tick-borne disease caused by Anaplasma phagocytophilum . Sero-epidemiological data demonstrate that this pathogen has a worldwide distribution. The diagnosis of HGA requires high index clinical suspicion, even in endemic areas. In recent years, increasingly been reported from Asia and described China, Japan, Korea. We serologically molecularly screened 467 patients with suspicion Anaplasmosis. present study describes...
Hospital-acquired infections (HAIs) pose a significant risk to global health, impacting millions of individuals globally. These have increased rates morbidity and mortality due the prevalence widespread antimicrobial resistance (AMR). Graphene-based nanoparticles (GBNs) are known possess extensive properties by inflicting damage cell membrane, suppressing virulence, inhibiting microbial biofilms. Developing alternative therapies for HAIs addressing AMR can be made easier more affordable...
Malignant peripheral nerve sheath tumor (MPNST) is a rare that accounts for 5% of all thoracic neoplasm usually located in the posterior mediastinum and generally associated with poor outcome. We present case MPNST anterior presenting location leading to diagnostic dilemmas treated primarily by surgical resection.
Abstract Background Sepsis is common in cirrhosis and often a result of immune dysregulation. Specific stimuli pathways inter‐cellular communications between cells sepsis are incompletely understood. Immune cell‐derived extracellular vesicles (EV) were studied to understand mechanisms cirrhosis. Methods EV measured patients [Child‐Turcotte‐Pugh (Child) score A, n = 15; B 16; C 43 Child‐C with (n 38)], healthy controls (HC, 11). In vitro vivo functional relevance associated was investigated....
Introduction Yoga has been demonstrated to have a range of beneficial effects on individuals with substance use disorders, including opioid disorders. We initiated randomized clinical trial find out the efficacy add-on yoga among patients dependence stabilized treatment whether it led improvement in sleep and quality life. However, rate enrolment into study was quite low. Objectives In this interim analysis, we present preliminary data reasons for non-enrolment trial. Methods The...
Hepatopulmonary syndrome (HPS) is a pulmonary vasculature complication in the setting of liver disease that characterized by pathological vasodilation resulting arterial oxygenation defects. We investigated role extracellular vesicles (EV) cirrhosis patients with HPS, as well functional effect EV administration common bile duct ligation (CBDL) HPS mouse model. A total 113 were studied: 42 (Gr. A) and 71 B) without 22 healthy controls. Plasma levels associated endothelial cells, epithelial...
Background and AimsCirrhosis patients exhibit cytopenia, and, at times refractory neutropenia to granulocyte colony-stimulating factor (G-CSF), which acts through the CSF3-receptor (CSF3R), changes in CSF3R can affect response. We conducted this study assess status its relevance cirrhotic patients.
Abstract Introduction: Cirrhosis patients exhibit cytopenia and variable response to GCSF, with benefits in early cirrhosis. GCSF acts through the CSF3-receptor (CSF3R), changes CSF3R can affect response. We investigated possible mechanism for lack of efficacy advanced cirrhosisMethodsCirrhotic (n = 127) controls 26) who underwent clinically indicated bone marrow (BM) examination were studied. BMs assessed RNA sequencing, qRT-PCR, immunohistochemistry (IHC) associated genes. Circulating...
Background: Treatment-related swallowing dysfunction still represents a significant clinical issue affecting the quality of life head and neck cancer (HNC) patients following radiation therapy (RT) or chemoradiation (CRT). Aim: The aim study was to evaluate incidence RT CRT by fiberoptic endoscopic evaluation (FEES) analyze FEES findings in reference patient-, tumor- treatment-related factors. Materials Methods: This prospective included histopathological-proven HNC undergoing objective...
Abstract Poster session 1, September 21, 2022, 12:30 PM - 1:30 Objective This study aimed to evaluate the antifungal and anti-biofilm activities of silver nanoparticles synthesized using Trillium govanianum, a trans-Himalayan medicinal plant extract, against multidrug-resistant Candida auris. Methods Silver (AgNPs) were by adopting green approach. Optimization characterization TG-AgNPs carried out UV-VIS spectroscopy, TEM, FTIR. Minimum inhibitory concentration (MIC), minimum fungicidal...
Necrotizing Enter colitis (NEC) is the devastating disease that affects mostly intestine of premature infants. The wall invaded by bacteria, which cause local infection and inflammation can ultimately destroy bowel. NEC develop in any new born within 2 weeks after birth. However it most common pre mature infants.NEC be staged into three groups, to guide appropriate treatment based on work Bell et al. . In general, stage I II are managed medically whereas III surgically.Trigger factors (i.e....