A5077112947- Cell Adhesion Molecules Research
- Glioma Diagnosis and Treatment
- Caveolin-1 and cellular processes
- Physics of Superconductivity and Magnetism
- Advanced Radiotherapy Techniques
- Medical Imaging Techniques and Applications
- S100 Proteins and Annexins
- Advanced Condensed Matter Physics
- Advanced X-ray and CT Imaging
- Magnetic and transport properties of perovskites and related materials
- Barrier Structure and Function Studies
- Magnetic properties of thin films
- Radiation Dose and Imaging
- Radiation Therapy and Dosimetry
- Phase-change materials and chalcogenides
- Glass properties and applications
- Hedgehog Signaling Pathway Studies
- Cancer, Hypoxia, and Metabolism
- Prostate Cancer Treatment and Research
- Meningioma and schwannoma management
- Terahertz technology and applications
- Cancer Cells and Metastasis
- Thermal Expansion and Ionic Conductivity
- Trigeminal Neuralgia and Treatments
- Neurosurgical Procedures and Complications
Princess Grace Hospital Centre
2013-2024
Scientific Centre of Monaco
2020
University of Central Florida
2008
Centre National de la Recherche Scientifique
1994-2004
Laboratoire de Physique des deux infinis Bordeaux
2004
Institut National de Physique Nucléaire et de Physique des Particules
2004
Laboratoire Léon Brillouin
1994-1998
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
1994-1996
CEA Paris-Saclay
1994-1996
Laboratoire d’Electrochimie et de Physico-chimie des Matériaux et des Interfaces
1993
Inelastic-neutron-scattering measurements have been performed to determine the imaginary part of dynamical susceptibility, \ensuremath{\chi}\ensuremath{''}(Q,\ensuremath{\omega}), a ${\mathrm{YBa}}_{2}$(${\mathrm{Cu}}_{1\mathrm{\ensuremath{-}}\mathit{y}}$${\mathrm{Zn}}_{\mathit{y}}$${)}_{3}$${\mathrm{O}}_{6.97}$ sample exhibiting superconducting transition at ${\mathit{T}}_{\mathit{c}}$=69 K. Zinc substitution induces striking modifications energy dependence...
Abstract Polycrystalline samples of perovskite‐structured BaCeO 3 and SrCeO were studied by Raman scattering spectroscopy in the temperature range 77–983 K. Changes spectra with are explained terms a second‐order phase transition ( D 2 h → 4 ) at T 0 = 427 Analysis dependence soft modes suggests partial displacive character. A dramatic decrease band intensity above 1000 K indicates to cubic O structure, for which no bands expected. The indicate that transitions occur Room doped various rare...
To assess the feasibility and benefit of integrating four-dimensional (4D) Positron Emission Tomography (PET) - computed tomography (CT) for liver stereotactic body radiation therapy (SBRT) planning.8 patients with 14 metastases were accrued in study. They all underwent a non-gated PET 4D centered on liver. The same CT scan was used attenuation correction, registration, considered planning SBRT planning. Six phases reconstructed each PET. By applying an individualized threshold to PET,...
Abstract The purpose of this work is to assess eight detectors performance for output factor ( OF ), percent depth dose PDD and beam profiles in a 6‐ MV Clinac stereotactic radiosurgery mode cone irradiation using Monte Carlo simulation as reference. Cones with diameters comprised between 30 4 mm have been studied. evaluated were ionization chambers: pinpoint 3D, diodes: SRS , P E, Edge, MicroDiamond EBT 3 radiochromic films. results showed that pinpoints underestimate up −2.3% ≥10 down −12%...
Abstract Medulloblastoma is one of the most prevalent solid tumors found in children, occurring brain's posterior fossa. The standard treatment protocol involves maximal resection surgery followed by craniospinal irradiation and chemotherapy. Despite a long-term survival rate 70%, wide disparities among patients have been observed. identification pertinent targets for both initial recurrent medulloblastoma cases imperative. Both primary are marked their aggressive infiltration into...
Medulloblastoma, a malignant pediatric brain tumor, has poor prognosis upon relapse, highlighting critical clinical need. Our previous research linked medulloblastoma cell radioresistance to integrin-αvβ3 expression. β3-depleted (β3_KO) cells exhibit lipid hydroxyperoxide accumulation after radiotherapy, indicating ferroptosis, regulated death induced by ROS and inhibited antioxidants such as cysteine, glutathione (GSH), peroxidase 4 (GPx4). However, the link between αvβ3 expression,...
Light-ion microbeams provide a unique opportunity to irradiate biological samples at the cellular level and investigate radiobiological effects low doses of high linear energy transfer ionizing radiation. Since 1998 single-ion irradiation facility has been developed on focused horizontal microbeam line CENBG 3.5 MV Van de Graaff accelerator. This setup delivers in air single protons alpha particles few MeV onto cultured cells, with spatial resolution micrometers, allowing subcellular...
Abstract Purpose The main objective of this study was to evaluate the ability a large field Cadmium Zinc Telluride (CZT) camera estimate thyroid uptake (TU) on single photon emission computed tomography (SPECT) images with and without attenuation correction (Tomo-AC Tomo-NoAC) compared Planar acquisition in series 23 consecutive patients. secondary determine radiation doses for tracer administration additional Computed Tomography (CT) scan. Methods Cross-calibration factors were determined...
The output power of backward wave oscillators and carcinotrons decrease considerably at high frequencies. This drop in can be due to the increase losses manufacturing defects their delay lines. In this study, we present measurement methods setups developed for characterization delay-line performance. were validated on two scaled-down models a TH4229 carcinotron operating frequency bandwidths around 10 100 GHz. Measurements dispersion diagrams made using different couplings with propagating...
Abstract Background This study compares the outcome of patients suffering from medically refractory classical trigeminal neuralgia (TN) after treatment with radiosurgery using two different shot sizes (5- and 6-mm). Methods All included in this open, prospective, non-controlled were treated a single institution for TN (95 cases 93 patients) LINear ACcelerators (LINAC) single-dose 5-mm (43 cases) or 6-mm (52 cases). The target was positioned on intracisternal part nerve. Results mean Dmax...
Purpose: Partial Volume Effect (PVE) is not taken to account in clinical routine although it one of the major sources error quantification PET image especially small size lesion. Depending on its size, uptake lesion underestimated. It mainly depends spatial resolution system and chosen sampling. The purpose this study highlight difference witch characterizes camera. Methods: This was performed a new generation PET/CT (Siemens mCT), fitted with four rings time flight (TOF). We used an...
Inelastic neutron scattering measurements have been carried out on a YBa 2 (Cu 0.98 -Zn 0.02 ) 3 O 6+x single crystal in both underdoped (x = 0.7) and overdoped 0.97) regimes. In the zinc substituted system, spin dynamics is drastically changed respect to pure compound: (i) "resonance peak" almost vanishes, (ii) gap filled, (iii) new antiferromagnetic excitations are found at low energy. These magnetic fluctuations, which persist normal state, account for local enhancement of AF correlations...
ABSTRACT Medulloblastoma (MB) is the most frequent solid tumor in children, localized brain’s posterior fossa. Its standard of care comprises maximal resection surgery followed by craniospinal irradiation and chemotherapy. Despite a long-term survival rate 70%, wide disparities among patients have been observed. Relevant targets for naive recurrent MB are urgently needed. Primary MBs characterized aggressive invasion into surrounding brain tissue, active angiogenesis, radioresistance....
Abstract Background This study compares the outcome of radiosurgery using two different shot sizes (5-mm and 6-mm) in patients suffering from medically refractory classical trigeminal neuralgia (TN). Methods All included this open, prospective, non-controlled were treated a single institution for TN (95 patients) by LINAC single-dose 5-mm (43 or 6-mm (52 patients). The target was positioned on intracisternal part nerve. Results Mean Dmax (D0.035) to brainstem that higher group: 12.6 Gy vs...