- X-ray Spectroscopy and Fluorescence Analysis
- Nuclear Physics and Applications
- Electron and X-Ray Spectroscopy Techniques
- Radiation Therapy and Dosimetry
- Ion-surface interactions and analysis
- Macrophage Migration Inhibitory Factor
- Effects of Radiation Exposure
- Nanoparticles: synthesis and applications
- Radiation Effects and Dosimetry
- Advanced X-ray Imaging Techniques
- Advanced X-ray and CT Imaging
- Marine Biology and Ecology Research
- Radiation Detection and Scintillator Technologies
- Nanocluster Synthesis and Applications
- Chemistry and Stereochemistry Studies
- Fluorine in Organic Chemistry
- Radioactive element chemistry and processing
- Radiation Effects in Electronics
- Trace Elements in Health
- Electrochemical Analysis and Applications
- Marine and environmental studies
- Coastal and Marine Management
- Diatoms and Algae Research
- Coastal wetland ecosystem dynamics
- Photoacoustic and Ultrasonic Imaging
Laboratoire de Physique des deux infinis Bordeaux
2014-2025
Centre National de la Recherche Scientifique
2005-2025
Université de Bordeaux
2005-2025
Laboratoire des Sciences de l'Environnement Marin
2019-2021
Ifremer
2020-2021
Université de Bretagne Occidentale
2021
Institut de Recherche pour le Développement
2020-2021
Institut Universitaire Européen de la Mer
2020
Institut Sophia Agrobiotech
2018-2020
Université Côte d'Azur
2020
Geant4, a Monte Carlo Simulation Toolkit extensively used in bio-medical physics, is continuous evolution to include newest research findings improve its accuracy and respond the evolving needs of very diverse user community. In 2014, G4-Med benchmarking system was born from effort Geant4 Medical Benchmarking Group, benchmark monitor for medical physics applications. The first described our Physics Special Report published 2021. Results tests were reported 10.5. this work, we describe...
Purpose:Track structure Monte Carlo (MC) codes have achieved successful outcomes in the quantitative investigation of radiation-induced initial DNA damage. The aim present study is to extend a Geant4-DNA radiobiological application by incorporating feature allowing for prediction rejoining kinetics and corresponding cell surviving fraction along time after irradiation, Chinese hamster V79 line, which one most popular widely investigated lines radiobiology.Methods:We implemented Two-Lesion...
Although titanium dioxide nanoparticles (TiO2 NPs) have been extensively studied, their possible impact on health due to specific properties supported by size and geometry, remains be fully characterized support risk assessment. To further document NPs biological effects, we investigated the of TiO2 morphology outcomes. this end, were synthesized as nanoneedles (NNs), titanate scrolled nanosheets (TNs), gel-sol-based isotropic (INPs) tested for perturbation cellular homeostasis (cellular ion...
Abstract Fluorophobic‐driven assemblies of gold nanomaterials were stabilized into water‐dispersible fluorous supraparticles by the film‐forming protein hydrophobin II. The strategy makes use different dimensions to engineer size and inner functionalization resulting confined space. compartments allow efficient encapsulation transport high loadings partially fluorinated drug molecules in water.
Assessing in situ nanoparticles (NPs) internalization at the level of a single cell is difficult but critical task due to their potential use nanomedicine. One main actual challenges control number internalized NPs per cell. To detect, track, and above all quantify cell, we propose an approach based on multimodal correlative microscopy (MCM), via complementarity three imaging techniques: fluorescence (FM), scanning electron (SEM), ion beam analysis (IBA). This MCM was performed targeted...
An irradiation facility, able to expose cellular and subcellular targets a precise number of particles, has been developed at CENBG for applications in radiobiology. The development this facility was based on an existing horizontal focused microbeam the early 90’s material analysis. focusing properties line allow delivering proton or alpha particle beams 1–3.5MeV energy range with spatial resolution down about 1μm under vacuum. For living cells, removable stage extract beam into air while...
Macrophage migration inhibitory factors (MIF) are multifunctional proteins regulating major processes in mammals, including activation of innate immune responses. MIF also play a role immunity invertebrate organisms or serve as virulence parasitic organisms, raising the question their evolutionary history. We performed broad survey presence absence and relationships across 803 species plants, fungi, protists, animals, explored potential relation with taxonomic status, ecology, lifestyle...
Bioindicators assess the mangroves ecological state according to types of pressures but they differ with ecosystem’s specificities. We investigated benthic meiofauna diversity and structure within low human-impacted in French Guiana (South America) response sediment variables various distances main city. Contaminant’s concentrations differed among stations, remained below toxicity guidelines. Meiofauna (Foraminifera, Kinorhyncha, Nematoda) however varied accordingly. Nematode’s...
Epibiosis is a common phenomenon in marine systems. In environments, ciliates are among the most organisms adopting an epibiotic habitus and nematodes have been frequently reported as their basibionts. present study, we report several new records of peritrich suctorian ciliates-nematode association worldwide: from deep-sea pockmark field NW Madagascar margin (Indian Ocean), shallow vent area Gulf Naples (Mediterranean, Tyrrhenian Sea), MPA Trieste Adriatic mangrove system French Guiana...
Light-ion microbeams provide a unique opportunity to irradiate biological samples at the cellular level and investigate radiobiological effects low doses of high linear energy transfer ionizing radiation. Since 1998 single-ion irradiation facility has been developed on focused horizontal microbeam line CENBG 3.5 MV Van de Graaff accelerator. This setup delivers in air single protons alpha particles few MeV onto cultured cells, with spatial resolution micrometers, allowing subcellular...
The use of a 1/spl mu/m ion beam as tomographic probe could constitute powerful tool for displaying the 3D structure samples few tens or hundreds micrometers thick in nondestructive way. At Centre d'Etudes Nucle/spl acute/aires de Bordeaux-Gradignan (CENBG), Gradignan, France, microtomography has been developed biomedical applications at cell level. internal cancer cells explored using scanning transmission microscopy (STIM) tomography, giving access to distribution mass density (in g/cm/sup...