A5103325198- Metabolism and Genetic Disorders
- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Dermatological and Skeletal Disorders
- Organ Transplantation Techniques and Outcomes
- Mitochondrial Function and Pathology
- Electrolyte and hormonal disorders
- Biochemical and Molecular Research
- Porphyrin Metabolism and Disorders
- Genetic Neurodegenerative Diseases
- Pulmonary Hypertension Research and Treatments
- Renal function and acid-base balance
- Diabetes and associated disorders
- Neonatal Health and Biochemistry
- Diet and metabolism studies
- Autoimmune Bullous Skin Diseases
- Skin and Cellular Biology Research
- Immunodeficiency and Autoimmune Disorders
- Urticaria and Related Conditions
- Adrenal Hormones and Disorders
- Congenital Heart Disease Studies
- Blood groups and transfusion
- Cardiac Arrhythmias and Treatments
- Blood disorders and treatments
- Hereditary Neurological Disorders
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
2010-2025
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2008-2019
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2008-2019
Universitat de Barcelona
2008-2019
Hospital Clínic de Barcelona
2002-2019
Escuela Superior Politécnica del Chimborazo
2019
Instituto Oncológico de Córdoba
2018
Center for Rheumatology
2013
Centro de Investigación Biomédica en Red
2012
Universidad del Salvador
2004-2008
In patients with cirrhosis and spontaneous bacterial peritonitis, renal function frequently becomes impaired. This impairment is probably related to a reduction in effective arterial blood volume associated high mortality rate. We conducted study determine whether plasma expansion intravenous albumin prevents reduces these patients.
The aim of this study was to investigate whether hyponatremia is a risk factor overt hepatic encephalopathy (HE) in cirrhosis.A total 61 patients with cirrhosis were evaluated prospectively for 1 year and all episodes HE recorded. Predictive factors analyzed using conditional model (Prentice, Williams, Peterson) recurrent events assess the relationship between time-dependent covariates. effects on brain concentration organic osmolytes 25 H-magnetic resonance spectroscopy.Twenty-eight...
Hyponatraemia is common in patients with advanced cirrhosis and associated remarkable changes brain cells, particularly a reduction myoinositol other intracellular organic osmolytes related to the hypoosmolality of extracellular fluid.It has been recently suggested that hyponatraemia may be an important factor development overt hepatic encephalopathy (HE).To test this hypothesis, we retrospectively analysed incidence predictive factors HE using database 70 included prospective study...
Terlipressin is frequently used in acute variceal bleeding due to its powerful effect on vasopressin V1 receptors. Although terlipressin also a partial agonist of renal V2 receptors, effects serum sodium concentration have not been specifically investigated. To examine the patients with portal-hypertensive bleeding, 58 consecutive severe treated were In whole population, decreased from 134.9 ± 6.6 mEq/L 130.5 7.7 ( P = 0.002). Thirty-nine (67%) had decrease ≥ 5 during treatment: 18 (31%),...
46 Background: Early detection of colorectal cancer (CRC) is key to survival. CRC screening compliance still low because either the invasive procedure (colonoscopy) or so-called "ick factor" (stool-based tests). Stool-based tests also lack ability detect advanced adenoma (CRC precursor). A blood-based test could improve adherence guidelines, but no one has so far been recommended due a sufficient sensitivity and specificity. Here we report potential clinical utility biomarker panel providing...
The alfa pump system has been proposed as a new treatment for the management of refractory ascites. removes ascites from peritoneal cavity to urinary bladder, producing continuous low‐volume paracentesis. aim study is investigate effects with pump™ on kidney and circulatory function in patients cirrhosis This was prospective including 10 Primary outcomes were changes glomerular filtration rate (GFR), assessed by isotopic techniques, arterial pressure, cardiac output, activity vasoconstrictor...
Patients with cirrhosis are frequently submitted to radiological procedures that require the administration of contrast media. Contrast media is a well-known cause renal failure, particularly in presence some predisposing conditions. However, it not known whether constitutes risk factor for media-induced failure. The aim this study was assess possible nephrotoxicity patients cirrhosis. In first protocol, function evaluated sensitive methods (glomerular filtration rate using iothalamate I 125...
Several experimental models of cirrhosis have shown dysregulation renal aquaporins in different phases liver disease. We investigated the urinary excretion both aquaporin-1 and aquaporin-2 patients with at stages Twenty-four-hour urine was collected from 11 healthy volunteers, 13 compensated (without ascites), 20 decompensated (11 ascites without failure 9 hepatorenal syndrome). Aquaporin-1 analyzed by immunoblotting. Urinary reduced compared to subjects. A progressive decrease observed as...