- IgG4-Related and Inflammatory Diseases
- Aortic aneurysm repair treatments
- Abdominal vascular conditions and treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Pancreatitis Pathology and Treatment
- Aortic Disease and Treatment Approaches
- Venous Thromboembolism Diagnosis and Management
- Vascular Procedures and Complications
- Infectious Aortic and Vascular Conditions
- Cardiac and Coronary Surgery Techniques
- Coronary Interventions and Diagnostics
- Peripheral Artery Disease Management
- Diagnosis and Treatment of Venous Diseases
- Cardiac Structural Anomalies and Repair
- Neuroendocrine Tumor Research Advances
- Cardiac Valve Diseases and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Cardiac Ischemia and Reperfusion
- Atrial Fibrillation Management and Outcomes
- Vascular Anomalies and Treatments
- Protease and Inhibitor Mechanisms
- Cardiac Arrhythmias and Treatments
- Eosinophilic Disorders and Syndromes
- Anesthesia and Neurotoxicity Research
Kanazawa Medical Center
2012-2025
National Hospital Organization
2010-2025
Kanazawa University
1996-2022
Pharmaceuticals and Medical Devices Agency
2016
Kanazawa Hospital
2001-2003
Tonami General Hospital
1997
Inflammatory abdominal aortic aneurysm (AAA) is a member of family disorders referred to as "chronic periaortitis" together with retroperitoneal fibrosis. Retroperitoneal fibrosis included in IgG4-related disease, which characterized by numerous infiltrating IgG4-positive plasma cells and high serum IgG4 concentrations. However, the relationship between disease inflammatory AAA has not been documented. In this study, we examined clinicopathologic characteristics (10 cases) atherosclerotic...
To report a rare and complicated case of immunoglobulin (Ig) G4-related periaortitis involving both the aortic wall retroperitoneum without aneurysmal formation.A 79-year-old man with IgG4-related suffered rupture despite normal caliber aorta after 6 months steroid therapy (20 mg/d). Endovascular repair an cuff sealed rupture. Steroid was halted 2 weeks later due to infection. Four later, biopsy during esophagogastroduodenoscopy investigate gastrointestinal bleeding suggested relapse IgG4-RD...
Background Arterial/aortic tertiary lymphoid organs (ATLOs), characterized by germinal centers, control local arterial immune responses. T follicular helper cells (Tfh), resident in regulate immunoglobulin production and center development. They consist of Tfh1, Tfh2, Tfh17 subsets. regulatory (Tfr) possess suppressive functions as migrate into centers. Immunoglobulin G4 (IgG4)–related diseases manifest vascular lesions frequently formed inflammatory aneurysms (IgG4‐related abdominal aortic...
Background: The objective of the present study was to assess hypothesis that introduction endovascular aneurysm repair (EVAR) into Japan has expanded indication abdominal aortic (AAA) without increasing surgical mortality. Methods and Results: From 10 national hospitals, we registered a total 2,154 consecutive patients (Open surgery [OS]: n=1,577, EVAR: n=577) over 8 years, divided 4 time periods: Group I (2005–2006: n=522), II (2007–2008: n=475), III (2009–2010: n=551), IV, (2011–2012:...
This multicenter, prospective, observational study aimed to compare Zilver PTX and Eluvia stents in real-world settings for treating femoropopliteal lesions as the differences 1-year outcomes of these have not been elucidated.Overall, 200 limbs with native artery disease were treated (96 limbs) or (104 at 8 Japanese hospitals between February 2019 September 2020. The primary outcome measure this was patency 12 months, defined a peak systolic velocity ratio ≤2.4, without clinically-driven...
Purpose: To report a rare case of mediastinal bronchial artery aneurysm successfully treated with an endovascular stent-graft. Case Report: A 79-year-old man history tuberculosis was admitted to our hospital complaining worsening hoarseness. Examination revealed large located near the origin artery. Since neither surgical intervention nor transcatheter embolization feasible, stent-graft repair performed using newly developed constructed from nitinol stent and thin membrane polyester....
Background: In 2018, diagnostic criteria were introduced for IgG4-related periaortitis/periarteritis and retroperitoneal fibrosis (PA/RPF). This study assessed the existing formulated an improved version.
Early outcomes of open abdominal repair (OS) versus endovascular (EVAR) for aortic aneurysm were retrospectively analyzed, after commercialized devices EVAR had become available in Japan.A total 781 consecutive patients (OS, n = 522; EVAR, 259) treated at ten medical centers between January 2008 and September 2010. The OS group comprised with preoperative shock (SOS, 34) without (NOS, 488).Patients the 3 years older than those NOS group. There was greater prevalence hostile abdomen, on...
Sac behavior after endovascular aneurysm repair (EVAR) for abdominal aortic aneurysms (AAAs) is considered as a surrogate the risk of late rupture. The purpose study to assess sac AAAs EVAR.Late enlargement (LSE) (≥5 mm) and shrinkage (LSS) were analyzed in 589 consecutive patients who registered at 14 national centers Japan. proportions had LSE 1, 3 5 years 2.6% ± 0.7%, 10.0% 1.6% 19.0% 2.9%. LSS 50.1% 59.2% 2.3% 61.7% 2.7%. Multiple logistic regression analysis identified two variables...
An immunohistochemical analysis was performed to clarify the healing process in implanted vascular grafts human. Eight woven Dacron and 6 expanded polytetrafluoroethylene were obtained following redo surgery, limb amputation, autopsy. The implantation periods ranged from 5 days 148 months. antibodies used for specific alpha-actin (smooth muscle cells), macrophages, von Willebrand factor (endothelial fibrin, elastin, collagen types 1-5, CD3 (T CD20 (B cells). At 24 after implantation, thrombi...