- Streptococcal Infections and Treatments
- Infant Nutrition and Health
- Sepsis Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Gut microbiota and health
- Nanoparticles: synthesis and applications
- Ferroptosis and cancer prognosis
- Neonatal and Maternal Infections
- Matrix Theory and Algorithms
- Electromagnetic Scattering and Analysis
- Moringa oleifera research and applications
- Clinical Nutrition and Gastroenterology
- Nanoplatforms for cancer theranostics
- Viral gastroenteritis research and epidemiology
- Graphene and Nanomaterials Applications
- MicroRNA in disease regulation
- Immune cells in cancer
- Dietary Effects on Health
- Garlic and Onion Studies
- Cancer, Hypoxia, and Metabolism
- Numerical methods for differential equations
- Dysphagia Assessment and Management
- Pomegranate: compositions and health benefits
- Pediatric Hepatobiliary Diseases and Treatments
- Spinal Cord Injury Research
Nanjing Medical University
2020-2024
Jiangsu Province Hospital
2020-2024
Guangdong University of Technology
2016-2021
Children's Hospital of Chongqing Medical University
2015-2016
China International Science and Technology Cooperation
2016
Chongqing Medical University
2015-2016
Anhui Provincial Hospital
2016
Anhui Medical University
2016
Xi’an University of Posts and Telecommunications
2014
Effects of green-synthesized silver nanoparticles on lung cancer cells in vitro and grown as xenograft tumors vivo Yan He,1,* Zhiyun Du,1,* Shijing Ma,1 Yue Liu,2 Dongli Li,1 Huarong Huang,1 Sen Jiang,1 Shupeng Cheng,1 Wenjing Wu,1 Kun Zhang,1 Xi Zheng1,2 1Allan H Conney Laboratory for Anticancer Drug Research, School Chemical Engineering Light Industry, Guandong University Technology, Guangzhou, People’s Republic China; 2Susan Lehman Cullman Cancer Department Biology, Ernest Mario...
Metal nanoparticles, particularly silver nanoparticles (AgNPs), are developing more important roles as diagnostic and therapeutic agents for cancers with the improvement of eco-friendly synthesis methods. This study demonstrates biosynthesis, antibacterial activity, anticancer effects using Dimocarpus Longan Lour. peel aqueous extract. The AgNPs were characterized by UV-vis absorption spectroscopy, X-ray diffraction (XRD), high-resolution transmission electron microscopy (HRTEM), scanning...
Necrotizing enterocolitis (NEC) in neonates is devastating, and risk-factor identification crucial. This study aimed to evaluate risk factors for NEC different gestational age (GA) groups.Risk associated with were investigated using a retrospective case-control design. Patients Bell's Stage NEC≥II divided into three groups based on GA: I, <34 weeks; II, ≥34 weeks but <37 III, ≥37 weeks. Each case was paired two GA- weight-matched controls. Data collected from medical records, univariate...
In the development of immunotherapies in gliomas, tumor microenvironment (TME) needs to be investigated. We aimed construct a prognostic microenvironment-related immune signature via ESTIMATE (PROMISE model) for glioma.Stromal score (SS) and (IS) were calculated each glioma sample cancer genome atlas (TCGA), differentially expressed genes (DEGs) identified between high-score low-score groups. Prognostic DEGs selected univariate Cox regression analysis. Using lower-grcade (LGG) data set TCGA,...
Gut microbiota are the candidate biomarkers for neurogenic bowel dysfunction (NBD) in patients with spinal cord injury (SCI). We aimed to identify common features between varying degree of thoracic SCI and healthy individuals subpopulations correlated serum biomarkers. Twenty-one complete (CTSCI), 24 incomplete (ITSCI), (HC) were enrolled this study. Fresh stool samples clinical data collected from all participants, their functions assessed. Microbial diversity composition analyzed by...
Aim Neonatal sepsis ( NS ) sustains high mortality and morbidity in China, but data on the epidemiology antimicrobial resistance patterns of pathogens are limited. Methods The clinical features, aetiology culture‐proven were analysed over a period 25 years metropolitan city Chongqing Southwest China. Results occurrence rates neonatal early‐onset EOS found to gradually decrease while late‐onset LOS was kept stable from 1990 2014. Although coagulase‐negative staphylococcus CoNS accounted for...
Abstract Acanthopanax trifoliatus (L.) Merr (AT) is a medicinal and edible plant with high nutritional value. The biological activity of A. its basis for injury treatment are explored in this paper. AT was ethanol‐extracted then refined separately petroleum ether, chloroform, ethyl acetate, n‐butanol. Active ingredients were analyzed, anti‐bacterial, anti‐inflammatory, analgesic, hemostatic effects explored. Petroleum ether layer (PEL) extract produced the strongest antibacterial effect....
Abstract Increasing evidence has demonstrated that cancer cell metabolism is a critical factor in tumor development and progression; however, its role glioblastoma (GBM) remains limited. In the present study, we classified GBM into three subtypes (MC1, MC2, MC3) through cluster analysis of 153 samples from RNA-sequencing data The Cancer Genome Atlas (TCGA) based on 2752 metabolism-related genes (MRGs). We further explored prognostic value, metabolic signatures, immune infiltration,...
Prostate cancer (PCa) is a common among males and leading cause of deaths. Docetaxel (DOC) was recommended in guidelines as the first first-line drug PCa; however, treatment with high doses DOC ultimately results resistance. This study examined proliferation, viability, apoptosis VCaP cells evaluated by MTT assay, trypan blue exclusion morphological assessments to investigate effects mechanisms action impressic acid (E12-1) or acankoreanogein (E13-1), isolated from Acanthopanax trifoliatus...
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Background: Alzheimer's Disease (AD) is the most prevalent type of dementia. The early change gut microbiota a potential biomarker for preclinical AD patients. Objective: study aimed to explore changes in characteristics patients, including those with Subjective Cognitive Decline (SCD) and Mild Impairment (MCI), detect correlation between cognitive performances. Methods: This included 117 participants [33 MCI, 54 SCD, 30 Healthy Controls (HC)]. We collected fresh fecal samples blood from all...