A5102007871- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Metal-Organic Frameworks: Synthesis and Applications
- Magnetism in coordination complexes
- Catalytic Cross-Coupling Reactions
- Catalytic C–H Functionalization Methods
- Crystal structures of chemical compounds
- Liver Disease Diagnosis and Treatment
- Chemical Synthesis and Analysis
- Market Dynamics and Volatility
- Polyoxometalates: Synthesis and Applications
- Crystallography and molecular interactions
- Synthesis of heterocyclic compounds
- Synthesis and Characterization of Heterocyclic Compounds
- Cardiovascular Function and Risk Factors
- Computational Drug Discovery Methods
- 3D Printing in Biomedical Research
- Peroxisome Proliferator-Activated Receptors
- Protein Tyrosine Phosphatases
- Vehicle emissions and performance
- Sustainable Building Design and Assessment
- Advanced Glycation End Products research
- Energy, Environment, and Transportation Policies
- Microstructure and Mechanical Properties of Steels
- Ionic liquids properties and applications
Zunyi Medical University
2023-2025
Hangzhou Medical College
2022-2025
Jiangsu University
2022-2025
Yangtze University
2024
Guangxi University
2024
Beijing Technology and Business University
2022-2024
Northwestern Polytechnical University
2024
China National Petroleum Corporation (China)
2024
Shenyang Institute of Automation
2023
Chinese Academy of Sciences
2009-2023
Nanozymes as artificial enzymes that mimicked natural enzyme-like activities have received great attention in cancer diagnosis and therapy. Biomimetic nanozymes require more consideration regarding complicated tumor microenvironments to mimic biological enzymes, thus achieving superior nanozyme activity vivo. Here we report a biomimetic hybrid (named rMGB) which integrates enzyme glucose oxidase (GOx) with manganese dioxide (MnO2) by mutual promotion for maximizing the enzymatic of MnO2 GOx....
Utilizing the ubiquitous fog in nature to create decentralized energy-harvesting devices, free from geographical and hydrological constraints, presents an opportunity foster sustainable power generation. Extracting electrical energy relies heavily on fog-digesting performance. Improving efficiency of fogwater utilization remains a formidable challenge for existing technologies. Inspired by water-harvesting behavior
Increasing evidence implicates chronic inflammation as the main pathological cause of diabetic nephropathy (DN). Exploration key targets in inflammatory pathway may provide new treatment options for DN. We aimed to investigate role Src homology 2–containing protein tyrosine phosphatase 2 (SHP2) macrophages and its association with The upregulated phosphorylation SHP2 was detected both patients diabetes a mouse model. Using macrophage-specific SHP2-knockout (SHP2-MKO) mice SHP2fl/fl injected...
Abstract Hemostatic materials facilitate rapid hemostasis and significantly mitigate the potential of fatal hemorrhage in civilian military traumas. However, most existing hemostatic are limited material‐dependent forms fail to integrate multifunctionality, thus constraining their versatility for differing settings wound healing capacity. Herein, a facile, versatile armor strategy is proposed endow various biomaterials with hemostasis, infection prevention, tissue capabilities. The...
Two homochiral enantiomers {(EMIM)[Zn(SIP)(IM)]}n (1a and 1b, EMIM = 1-ethyl-3-methylimidazolium) possessing chiral (10,3)-a topology constructed from an achiral rigid 5-sulfoisophthalate (SIP) ligand imidazole (IM) have been obtained by spontaneous resolution under ionothermal conditions. The show second-order nonlinear optical effects photoluminescence.
A new and efficient method for the synthesis of aza-fused polycyclic quinolines (e.g., benzimidazo[1,2-a]quinolines) is described. This protocol includes an intermolecular condensation followed by a copper-catalyzed intramolecular C−N coupling reaction. The applied to wide range 2-iodo, 2-bromo, 2-chloro aryl aldehyde substrates yield in good yields.
A chiral heteometallic compound, [(EMIM)NaCu(1,4-ndc)2]n (1), constructed from the achiral 1,4-naphthalenedicarboxylate (1,4-ndc) ligand has been ionothermally synthesized and structurally magnetically characterized. The induction effect of enantiopure 1-ethyl-3-methylimidazolium (EMIM) L-lactate additive in ionothermal reaction is briefly discussed.
Abstract Background and Purpose Doxorubicin (DOX), an anthracycline chemotherapeutic agent, whose use is limited owing to its dose‐dependent cardiotoxicity. Mitochondrial oxidative stress plays a crucial role in the pathogenesis of DOX‐induced cardiotoxicity (DIC). Trilobatin (TLB), naturally occurring food additive, exhibits strong antioxidant properties, but cardioprotective effects DIC unclear. This study investigates effect TLB on DIC. Experimental Approach DOX was used generate vivo...
BACKGROUND: Pathological cardiac hypertrophy can result in heart failure. Protein dephosphorylation plays a primary role the mediation of various cellular processes cardiomyocytes. Here, we investigated effects protein tyrosine phosphatase, PRL2 (phosphatase regenerative liver 2), on pathological hypertrophy. METHODS: The knockout mice were subjected to angiotensin II infusion or transverse aortic constriction induce myocardial and dysfunction. RNA-sequencing analysis was performed explore...
The psychological development of college students is closely linked to their environmental contexts, which significantly impacts mental health. Traditional health education often neglects this ecological perspective, resulting in limited methods and disconnection from students' real-life environments. This paper explores how psychology can enhance education. Using an integrated learning algorithm the Xgboost model, authors identify key factors influencing well-being. findings inform a...
A straightforward synthesis of indole-2-carboxylic esters was developed through a ligand-free copper-catalysed condensation/coupling/deformylation cascade process from 2-halo aryl aldehydes or ketones with ethyl isocyanoacetate. The reactions proceeded well for most the 2-iodo-, bromo-, and chloro-subtrates under room temperature mild conditions.
An organic ligand 4-(1,2,4-triazol-1-yl) benzoic acid (Htzbc) with a nonlinear optical (NLO) chromophore has been synthesized. Reaction of Zn(NO3)2 Htzbc in 1-n-butyl-3-methylimidazolium tetrafluoroborate ionic liquid afforded compound Zn(tzbc)2 (1). The solid and 1 crystallize the acentric Pn Cc space groups, respectively. tetrahedral Zn2+ center coordinates to two triazole nitrogen atoms carboxylate oxygen from four tzbc– ligands, leading noncentrosymmetric 5-fold interpenetrating...
The reactions of Ln(NO3)3 with 2,5-dihydroxy-1,4-benzenedicarboxylic acid (H2-DHBDC) under solvothermal conditions produce a series isomorphous lanthanide coordination polymers the empirical formula {[Ln2(DHBDC)3(DMF)4](DMF)2}n (Ln = La(1), Nd(2), Sm(3), Gd(4), and Er(5)). Compound contains dinuclear Ln2(COO)6 units, which are linked by –C6H2(OH)2– spacers to form three-dimensional framework exhibiting α-Po topology (pcu-(412·63) net) based on nodes. shows one-dimensional open channels that...
Echinochloa crus-galli var. mitis has rarely been reported for herbicide resistance, and no case of quinclorac resistance so far. Synthetic auxin-type is used extensively to control rice weeds worldwide. A long history using in Chinese fields escalated the E. against this herbicide. Bioassays Petri plates pots exhibited four biotypes that evolved into ranking as JS01-R > AH01-R JS02-R JX01-R from three provinces China. Ethylene production these was negatively correlated with level positively...
Diabetic nephropathy (DN) represents the most serious complication of diabetes. Previous studies have shown that activation nuclear factor kappa B (NF-κB) and mitogen-activated protein kinase (MAPK) are linked to inflammation in development DN. Sclareol, a natural diterpene compound, has beneficial effects on inflammation. Thus, we hypothesized sclareol might prevent DN via anti-inflammatory actions. This study aimed investigate actions progression DN, explored related molecular mechanism....
It is well known that both fluid mechanics and matrix stiffness present within the cellular microenvironments play an essential role in physiological pathological processes of cells. However, so far, knowledge interplay tuning mechanical behaviors single cells still extremely limited. Particularly, atomic force microscopy (AFM) now important standard tool for characterizing properties living Nevertheless, studies utilizing AFM to detect are commonly performed static medium conditions, which...
Quantitative structure-activity relationship (QSAR) is a cost-effective solution to directly and accurately estimating the environmental safety thresholds (ESTs) of pollutants in ecological risk assessment due lack toxicity data. In this study, QSAR models were developed for Predicted No-Effect Concentrations (PNECs) petroleum hydrocarbons their derivatives (PHDs) under dietary exposure, based on quantified molecular descriptors obtained PNECs 51 PHDs with given acute or chronic...