A5102571801- Advanced Battery Materials and Technologies
- Topic Modeling
- Animal Disease Management and Epidemiology
- Advancements in Battery Materials
- Natural Language Processing Techniques
- RNA modifications and cancer
- Supercapacitor Materials and Fabrication
- Advanced Battery Technologies Research
- Immune cells in cancer
- Vector-Borne Animal Diseases
- Cancer-related molecular mechanisms research
- Ferroptosis and cancer prognosis
- Epigenetics and DNA Methylation
- MicroRNA in disease regulation
- Ubiquitin and proteasome pathways
- Animal Virus Infections Studies
- T-cell and Retrovirus Studies
- Semantic Web and Ontologies
- interferon and immune responses
- Multimodal Machine Learning Applications
- Cancer-related gene regulation
- Advanced Text Analysis Techniques
- RNA Interference and Gene Delivery
- Data Quality and Management
- Viral Infections and Vectors
Collaborative Innovation Center of Chemistry for Energy Materials
2025
Fudan University
2024-2025
Beijing University of Posts and Telecommunications
2023-2024
Ministry of Education of the People's Republic of China
2020-2024
Xidian University
2018-2024
South China University of Technology
2021-2024
Institute of Polymers
2024
Yangzhou University
2013
Fiber solar cells as promising wearable power supplies have attracted increasing attentions recently, while further breakthrough on their conversion efficiency (PCE) and realization of multicolored appearances remain urgent needs particularly in real-world applications. Here, a fiber-dye-sensitized cell (FDSSC) integrated with light diffusion layer composed alumina/polyurethane film the outmost encapsulating tube made from phosphors/TiO
Flexible batteries such as scalable fiber‐shaped lithium‐ion (FLIBs) hold great potential for powering wearable electronics due to their excellent electrochemical performance, flexibility, and weavability. However, the use of organic liquid electrolytes raises serious safety concerns, including leakage combustion hazards. In this study, we develop fire‐resistant lithium cobalt oxide/graphite FLIBs by employing an in‐situ polymerized gel polymer electrolyte (GPE) incorporating...
Flexible batteries such as scalable fiber‐shaped lithium‐ion (FLIBs) hold great potential for powering wearable electronics due to their excellent electrochemical performance, flexibility, and weavability. However, the use of organic liquid electrolytes raises serious safety concerns, including leakage combustion hazards. In this study, we develop fire‐resistant lithium cobalt oxide/graphite FLIBs by employing an in‐situ polymerized gel polymer electrolyte (GPE) incorporating...
Abstract The rise of wearable electronics demands flexible energy storage solutions like fiber devices (FESDs), known for their flexibility and portability. However, it remains difficult existing fabrication methods (typically, finite‐coating, thermal‐drawing, solution‐extrusion) to simultaneously achieve desirable electrochemical performances fast production FESDs. Here, a new scalable coating‐extrusion method is developed, utilizing novel extruded spinneret with tapered apertures create...
The etiology of cancer includes aberrant cellular homeostasis where a compromised RNA regulatory network is prominent contributing factor. In particular, noncoding RNAs including microRNAs (miRNAs) and long (lncRNAs) were recently shown to play important roles in the initiation, progression, metastasis human cancers. Nonetheless, mechanistic understanding functions lung squamous cell carcinoma (LUSC) lacking. To fill this critical gap knowledge, we obtained mRNA, miRNA, lncRNA expression...
An immunosuppressive state is regulated by various factors in the tumor microenvironment (TME), including, but not limited to, metabolic plasticity of cells and cytokines secreted these cells. We used single-cell RNA-sequencing (scRNA-seq) data applied flux estimation analysis to characterize link between metabolism cellular function within hypoxic TME colorectal (CRC) lung cancer. In terms heterogeneity, we found myeloid potentially inclined accumulate glutamine glutamate. particular,...
Various studies have shown that lysine acetyltransferase 2A (KAT2A), E2F transcription factor 1 (E2F1), and ubiquitin conjugating enzyme E2 C (UBE2C) genes regulated the proliferation migration of tumor cells through regulating cell cycle. However, there is a lack in-depth systematic research on their mechanisms action. This study analyzed The Cancer Genome Atlas (TCGA) to screen potential candidate regulation network KAT2A E2F1 complex in pan-cancer. Quantitative real-time PCR (qRT-PCR)...
Abstract Fiber lithium‐ion batteries (FLIBs) hold great promise for powering wearable electronics. However, their practical application is hindered by limited cycle and calendar life, primarily due to the loss of active Li caused water vapor permeation through encapsulation layer. To address this challenge, a low‐permeability high‐flexibility tetrafluoroethylene hexafluoropropylene copolymer (FEP) tube presented continuously encapsulate FLIBs melting extrusion method. Owing inherent...
DNA damage repair (DDR) is critical in maintaining normal cellular function and genome integrity associated with cancer risk, progression, therapeutic response. However, there still a lack of thorough understanding the effects DDR genes’ expression level progression resistance. Therefore, we defined tumor-related score (TR-DDR score), utilizing levels 20 genes, to quantify tumor signature pathways tumors explore possible mechanism for among different cancers. The TR-DDR has remarkably...
Inactivated Sendai virus (HVJ-E) directly kills cancer cells by inducing apoptosis through a mechanism mediated Janus kinases/signal transducers and activators of transcription (JAK/STAT) signaling pathways. However, whether other pathways are involved remain largely unknown. This study aimed to investigate the underlying HVJ-E-induced in murine B16F10 melanoma cells. We found that HVJ-E induced cell via caspase pathway, particularly caspase-9, which mediates intrinsic apoptotic pathway....
The upregulated proline rich 11 (PRR11) plays a critical role in cancer progression. relevant biological functions of PRR11 pan-cancer development are not well understood. In the current study, we found that was 19 types compared with normal tissues and high-expressed predictor poor prognosis 10 by bioinformatics. Then showed interfering on three cell lines could greatly inhibit proliferation migration arrest cells to S phase vivo . Based RNA-seq, downregulation expression extremely suppress...
Renal cell carcinoma (RCC) is one of the most common malignant tumors kidney, presenting significant challenges for clinical diagnosis and treatment. Macrophages play crucial roles in RCC, promoting tumor progression warranting further investigation. Previous studies have identified
Skeletal muscle is one of the predominant sites involved in glucose disposal, accounting for approximately 80% postprandial uptake, and plays a critical role maintaining glycemic homeostasis. Dysregulation energy metabolism skeletal developing insulin resistance type 2 diabetes (T2D). Transcriptomic responses to exercise found that expression Klf3 was increased T2D Goto-Kakizaki (GK) rats decreased after with improved hyperglycemia resistance, implying might be associated sensitivity...
Abstract Scalable fiber lithium‐ion batteries (FLIBs) have garnered significant attention due to huge potential applications in wearable technology. However, their widespread been limited by inadequate cycle and calendar life, primarily the high permeability of encapsulation layer water vapor ambient air. To address this challenge, an ultra‐high barrier composite tube is developed blending polytrifluorochloroethylene (PCTFE) with organically modified montmorillonite (OMMT) for continuous...
Various studies have shown that the cell-cycle-related regulatory proteins UBE2C, PLK1, and BIRC5 promote cell proliferation migration in different types of cancer. However, there is a lack in-depth systematic research on mechanism these three as therapeutic targets. In this study, we found positive correlation between expression UBE2C PLK1/BIRC5 Cancer Genome Atlas (TCGA) database, revealing potential combination therapy candidate for pan-cancer. Quantitative real-time PCR (qRT-PCR),...
The tumor microenvironment plays a critical role in progression and immune regulation. As one of the most important components microenvironment, macrophages have become new therapeutic target for inhibiting progression. Despite well-documented anticancer activity cucurbitacin I, its effect on remains unclear. In this study, we established coculture system cancer cells under hypoxic conditions to simulate tumor-promoting environment mediated by M2-like macrophages. We determined whether I...
Hepatocellular carcinoma (HCC) is a highly detrimental cancer type and has limited therapeutic options, posing significant threats to human health. The development of HCC been associated with disorder in bile acid (BA) metabolism. In this study, we employed an integrative approach, combining various datasets omics analyses, comprehensively characterize the tumor microenvironment based on genes related BA Our analysis resulted classification samples into four subtypes (C1, C2a, C2b, C3)....
Most current Event Extraction (EE) methods focus on the high-resource scenario, which requires a large amount of annotated data and can hardly be applied to low-resource domains. To address EE more effectively with limited resources, we propose Demonstration-enhanced Schema-guided Generation (DemoSG) model, benefits from two aspects: Firstly, demonstration-based learning paradigm for fully use data, transforms them into demonstrations illustrate extraction process help model learn...
Classical swine fever (CSF) is a disease that characterized by diffuse hemorrhaging, high fever, and mortality rates. The pro-inflammatory characteristics of allograft inflammatory factor 1 (AIF1) have been well documented; however, insufficient attention has given to porcine AIF1. In the present study, AIF1 was identified as key player contributing CSFV Shimen infection in alveolar macrophage (PAM) 3D4/21 cell line. Our evaluation showed mRNA protein are expressed at time-dependent level...
Document-level event extraction (DEE) faces two main challenges: arguments-scattering and multi-event. Although previous methods attempt to address these challenges, they overlook the interference of event-unrelated sentences during detection neglect mutual different roles argument extraction. Therefore, this paper proposes a novel Schema-based Explicitly Aggregating (SEA) model limitations. SEA aggregates information into type role representations, enabling decoding records based on...