A5065507636- Ultrasound Imaging and Elastography
- Nanoparticle-Based Drug Delivery
- Breast Lesions and Carcinomas
- AI in cancer detection
- Nanoplatforms for cancer theranostics
- Photoacoustic and Ultrasonic Imaging
- Ultrasound and Hyperthermia Applications
- Ultrasonics and Acoustic Wave Propagation
- Prostate Cancer Treatment and Research
- Extracellular vesicles in disease
- Pediatric Hepatobiliary Diseases and Treatments
- Cancer-related Molecular Pathways
- Renal and related cancers
- Identification and Quantification in Food
- Cancer Research and Treatments
- Elbow and Forearm Trauma Treatment
- Genetic Mapping and Diversity in Plants and Animals
- Aquatic Invertebrate Ecology and Behavior
- Invertebrate Taxonomy and Ecology
- Uterine Myomas and Treatments
- RNA Interference and Gene Delivery
- Spinal Fractures and Fixation Techniques
- Hemodynamic Monitoring and Therapy
- Genomic variations and chromosomal abnormalities
- Ultrasound in Clinical Applications
The Seventh Affiliated Hospital of Sun Yat-sen University
2017-2025
Sun Yat-sen University
2016-2025
Sun Yat-sen Memorial Hospital
2014-2018
Oregon State University
2014
Shandong Ocean and Fisheries Department
2012
<title>Abstract</title> Neural-tumor electrophysiology—marked by pathological membrane potentials and ion channel dysregulation—emerges as actionable targets to curb tumor aggression. Yet, how neural-driven bioelectrical crosstalk dynamically regulates tumors within functional circuits remains elusive, demanding tools for real-time interaction decoding. Here, we present a machine learning-driven electrophysiological platform that integrates custom microfluidics with decoding of complex...
The purpose of this study was to analyze the ultrasonic elastography features phyllodes tumors breast comparing with fibroadenomas. A retrospective database queried for patients diagnosed as and fibroadenomas at Sun Yat-sen Memorial Hospital from January 2008 August 2012. Three hundred fifty lesions 323 consecutive were included in study. All cases examined by conventional ultrasonography ultrasound elastography. Ultrasound used calculate strain ratio bilateral tissue same depth reference....
Background This study aimed to confirm whether strain ratio should be added after evaluation of lesions with 5-point elasticity scoring for differentiating benign and malignant breast on ultrasonographic elastography(UE). Materials Methods From June 2010 March 2012, 1080 consecutive female patients were recruited into a multicenter retrospective study, which involved 8 centers across China. Each institutional ethic review board approved the all gave written informed consent. All underwent UE...
Abstract Ultrasonography (US) is frequently applied in clinical imaging because of its inherent merits compared with those other methods. Nanoparticle (NP)‐based and therapeutic modalities have been widely used their unique functionalities high performance. The report mainly about the classifications applications NPs for US‐based theranostic biomedicine. include single‐modality US imaging, multimodality high‐intensity focused US, US‐triggered drug release, US‐enhanced gene transfection,...
Ultrasonography (US) contrast imaging using US agents has been widely applied for the diagnosis and differential of tumors. Commercial have limited applications because their large size shorter time. At same time, desired therapeutic purpose cannot be achieved by applying only conventional agents. The development nanoscale with functions attracted increasing attention. In this study, we successfully developed DOX-loaded poly-1,6-hexanedithiol-sodium bicarbonate nanoparticles...
Breast lesions classified as BI-RADS-US 3 are probably benign and observation was recommended, while a considerable number of 4 were benign, resulting in excessive biopsies. We focus exclusively on hypothesize that improved diagnostic performance can be achieved by integrating real-time elastography (strain ratio) into the classification system. From April 2010 to September 2015, 1071 included final analysis. After conventional ultrasound examination, (2013) used evaluate lesions. Then...
Cell membrane-coated nanomaterials are increasingly recognized as effective in cancer treatment due to their unique benefits. This study introduces a novel hybrid membrane coating nanoparticle, termed cell (CCM)–outer vesicle (OMV)@Lip-indocyanine green (ICG), which combines CCMs with bacterial OMV encapsulate ICG-loaded liposomes. Comprehensive analyses were conducted assess its physical and chemical properties well functionality. Demonstrating targeted delivery capabilities good...
Pancreatic metastases account for only a small proportion of all pancreatic malignancies. Isolated metastasis from renal cell cancer (isPM-RCC) is extremely rare and may be difficult to differentiate more common primary neoplasms. A history nephrectomy crucial the diagnosis.We report case 64-year-old Asian man who was diagnosed with mass in head using computed tomography. He had no related symptoms, his medical unremarkable, except unilateral performed remove "benign" tumor 19 years ago. All...
Abstract Poor selectivity, low bioavailability and serious systemic side-effects have limited the application of traditional chemotherapy method for treatment prostate cancer. Stimuli-responsive drug delivery systems are mainly based on unique characteristics tumor microenvironment. In this study, GSH-sensitive poly-TTG-SS@DTX NPs (DTX-loaded poly-Tetraethylene glycol nanoparticles) were designed synthesized, which characterized with nanosized diameter (92.8 ± 2.5 nm) negatively charged...
Abstract Rationale: Giant uterine myomas may be life-threatening due to pressure effects on the lungs and other contiguous organs. Patient concerns: A 32-year-old pregnant Asian woman was admitted our hospital early in her pregnancy with a pre-pregnancy history of multiple myomas. Diagnosis: She diagnosed giant pregnancy. Interventions: No intervention performed woman. Outcomes: reduction tumor size disappearance blood supply were seen conventional contrast-enhanced ultrasounds (CEUS)...
Objective To investigate the clinical value of magnetic resonance cholangiopancreatography (MRCP) in preoperative evaluation patients with biliary calculus. Methods Clinical data 70 calculus Sun Yat-sen Memorial Hospital and Third Affiliated University from June 2012 to 2013 were retrospectively analyzed. There 38 males 32 females age ranging 18 87 years old median 52 old. The informed consents all obtained ethical committee approval was received. underwent ultrasound examination MRCP...
Objective Combination of nanoparticle with p53 and Rb gene therapy by targeting was applied to investigate its curative effect safety evaluation on colorectal rabbit hepatic VX2 metastasis for tumor eradication survival enhancement. Methods Recombinant expressing plasmids harboring wild type were cotransferred or transferred separately the emulsion PLL-nHAP nanoplex lipodiol through artery in a target manner. Subsequent co-expressions protein within treated tumors detected Western...
Objective To study the construction of phenylalanine-based poly(ester amide)sas drug delivery system and its inhibition in vitro prostate cancer cell LNCaP. Methods The amide)s nanoparticles were synthesized by nanoprecipitation. The morphology size distribution nanoparticle inspected transmission electron microscopy analyzer. Drug loading encapsulation rate measured using fragmentation precipitation method fluorescent phosphorescence spectrometer. Inhibition LNCaP doxorubicin-loaded...