A5020073643- Health Promotion and Cardiovascular Prevention
- Health disparities and outcomes
- Veterinary Medicine and Surgery
- Metabolism and Genetic Disorders
- Blood groups and transfusion
- Platelet Disorders and Treatments
- Diet and metabolism studies
- Healthcare Policy and Management
- Cardiac pacing and defibrillation studies
- Mechanical Circulatory Support Devices
- Drug-Induced Hepatotoxicity and Protection
- Endoplasmic Reticulum Stress and Disease
- Global Health Workforce Issues
- Pharmacological Effects of Natural Compounds
- Pancreatitis Pathology and Treatment
- Blood properties and coagulation
- Veterinary Oncology Research
- Plant Toxicity and Pharmacological Properties
- Cardiovascular Health and Risk Factors
- Eosinophilic Disorders and Syndromes
- Amoebic Infections and Treatments
- Animal health and immunology
- Primary Care and Health Outcomes
- Pediatric Hepatobiliary Diseases and Treatments
- Quality and Supply Management
Carbon Valley Animal Hospital
2021
Cornell University
2017
Public Health Wales
2015
University of Liverpool
2014
Liverpool City Council
2013
Gibraltar Health Authority
1997
Radioiodine (131 I) is effective treatment for hyperthyroidism in cats, but optimal dose to restore euthyroidism without inducing hypothyroidism unclear. Treatment-induced can lead azotemia and reduced duration of survival.To compare efficacy short-term outcomes low-dose 131 I versus higher, standard-dose as hyperthyroidism.A total 189 client-owned cats undergoing mild-to-moderate (serum T4 ≥ 4.0 μg/dL <13.0 μg/dL).Prospective, nonrandomized, cohort study comparing with either (2 mCi, n =...
Abstract Management of immune thrombocytopenia (ITP) in dogs and cats is evolving, but there are no evidence‐based guidelines to assist clinicians with treatment decisions. Likewise, the overall goals for ITP have not been established. Immunosuppressive doses glucocorticoids first line treatment, optimal regimens beyond remain uncertain. Additional options include secondary immunosuppressive drugs such as azathioprine, modified cyclosporine, mycophenolate mofetil, usually selected based on...
Objective To analyse the falls in coronary heart disease (CHD) mortality England between 2000 and 2007 quantify relative contributions from preventive medications population-wide changes blood pressure (BP) cholesterol levels, particularly by exploring socioeconomic inequalities. Design A modelling study. Setting Sources of data included controlled trials meta-analyses, national surveys official statistics. Participants English population aged 25+ 2000–2007. Main outcome measures Number...
To characterize findings in Shih Tzus with progressive superficial necrolytic dermatitis and degenerative vacuolar hepatopathy consistent hepatocutaneous syndrome.Retrospective case series.31 Tzus.Medical records were reviewed to obtain information on signalment, history, treatment, outcome, results of clinicopathologic testing, abdominal ultrasonography, histologic examination skin liver specimens. A pedigree analysis was performed.There 16 males 15 females. Median age at the time diagnosis...
Abstract Background Primary immune thrombocytopenia (pITP) in dogs presents a diagnostic challenge, and clinical markers of severity are lacking. Objectives Identify clinicopathologic features that differentiate pITP from secondary ITP (sITP) related to bleeding severity, transfusion, survival with pITP. Animals Ninety‐eight thrombocytopenic (58 40 sITP). Methods Client‐owned platelet counts <50 000/μL were enrolled prospective, multi‐institution cohort study. History treatment...
To analyse the trends and trend changes in myocardial infraction (MI) coronary heart disease (CHD) admissions, to investigate effects of 2007 smoke-free legislation on these trends, consider policy implications any findings.Liverpool (city), UK.Hospital episode statistics data all 56 995 admissions for CHD Liverpool between 2004 2012 (International Classification Diseases codes I20-I25 coded as an admission diagnosis within defined dates).Trend gradient change points (by regressions...
OBJECTIVE To characterize aminoaciduria and plasma amino acid concentrations in dogs with hepatocutaneous syndrome (HCS). ANIMALS 20 client-owned of various breeds ages. PROCEDURES HCS was definitively diagnosed on the basis liver biopsy specimens (n = 12), gross histologic appearance skin lesions (4), examination (2) presumptively cutaneous compatible clinicopathologic hepatic ultrasonographic (honeycomb or Swiss cheese pattern) findings (2). Amino heparinized urine (samples obtained within...
To characterize the frequency and type of bacterial infection by culture- immunohistochemical (IHC)-based methods determine impact on clinical features survival time in cats with suppurative cholangitis-cholangiohepatitis syndrome (S-CCHS).168 client-owned S-CCHS (cases).Clinical features, culture results, culture-inoculate sources, details were recorded. Cases subcategorized comorbidity (extrahepatic bile duct obstruction, cholelithiasis, cholecystitis, ductal plate malformation,...
There is strong evidence to suggest that social deprivation linked health inequalities. In the UK, concerns have been raised regarding disparities in outcomes of acute cardiac services within National Health Service (NHS). This study explored whether differences exist (a) elective hospital presentation time (b) indicators severity and disease burden (c) treatment (hospital stay mortality) on basis index multiple (IMD) status. was a retrospective analysis data from NHS databases for 13,758...
Abstract OBJECTIVE To characterize clinical, clinicopathologic, and hepatic histopathologic features outcome for dogs with probable ketoconazole-induced liver injury. ANIMALS 15 suspected injury that underwent biopsy. PROCEDURES Medical record data were summarized regarding signalment, clinical signs, clinicopathologic findings, concurrent medications, ketoconazole dose, treatment duration, outcome. RESULTS Median age body weight 8.2 years (range, 5 to years) 13.0 kg (28.6 lb; range, 38.0...
Background: Between 2000 and 2007, coronary heart disease (CHD) mortality rates in England plummeted by one third. An important part of this substantial CHD decline was achieved through reductions major cardiovascular risk factors (primary prevention). However, the relative contributions from medications population-wide changes remains unclear, particularly effects on health inequalities. Methods: Using a previously validated policy model, fall analysed. The factor declines asymptomatic...
Background Between 2000 and 2007, coronary heart disease (CHD) mortality rates in England plummeted by one third. An important part of this substantial CHD decline was achieved through reductions major cardiovascular risk factors (primary prevention). However, the relative contributions from medications population-wide changes remains unclear, particularly effects on health inequalities. Methods Using a previously validated policy model, fall analysed. The factor declines asymptomatic...