A5101715072- Electrospun Nanofibers in Biomedical Applications
- Stroke Rehabilitation and Recovery
- Gut microbiota and health
- Pharmacological Effects of Natural Compounds
- Telemedicine and Telehealth Implementation
- Cancer-related molecular mechanisms research
- Functional Brain Connectivity Studies
- Neurological Disease Mechanisms and Treatments
- Orthoptera Research and Taxonomy
- Advanced Sensor and Energy Harvesting Materials
- Transcranial Magnetic Stimulation Studies
- Tissue Engineering and Regenerative Medicine
- Nutritional Studies and Diet
- Circular RNAs in diseases
- Migraine and Headache Studies
- Plant and animal studies
- Insect and Pesticide Research
- Acute Myocardial Infarction Research
- Genetic Associations and Epidemiology
- Insect and Arachnid Ecology and Behavior
- Cardiovascular Function and Risk Factors
- Additive Manufacturing and 3D Printing Technologies
- Heart Failure Treatment and Management
- Mobile Health and mHealth Applications
- Immune Cell Function and Interaction
Harbin Medical University
2015-2025
Second Affiliated Hospital of Harbin Medical University
2019-2025
Ministry of Education of the People's Republic of China
2024-2025
University of North Carolina at Chapel Hill
2023-2025
Fujian University of Traditional Chinese Medicine
2023-2025
Children's Hospital of Fudan University
2025
Central South University
2022-2024
Chengdu University of Traditional Chinese Medicine
2021-2024
The First Affiliated Hospital, Sun Yat-sen University
2024
Sun Yat-sen University
2024
Electrospinning is a versatile technique for the construction of microfibrous and nanofibrous structures with considerable potential in applications ranging from textile manufacturing to tissue engineering scaffolds. In simplest form, electrospinning uses high voltage tens thousands volts draw out ultrafine polymer fibers over large distance. However, limits flexible combination material selection, deposition substrate, control patterns. Prior studies show that by performing well-defined...
Pectin, a complex hydrocolloid, attracts extensive attention and application stemming from its good emulsification. However, the source of emulsification remains conundrum. In this experiment, structures six kinds commercial pectin, including LM 101 AS (101), 104 (104), 121 SLOW SET (121), YM 150 H (150), 13 CG (13CG), β-PECTIN (β-P) were determined, effects pectin structure on emulsion emulsification, rheology in vitro digestibility studied. The results showed that β-P contained higher...
Background Intestinal microbiota homeostasis and the gut-brain axis are key players associated with host health alterations in metabolic, inflammatory, neurodegenerative disorders. Sepsis-associated encephalopathy (SAE), which is closely bacterial translocation, a common secondary organ dysfunction an urgent, unsolved problem affecting patient quality of life. Our study examined neuroprotective effects gut microbiome short-chain fatty acid (SCFA) metabolites on SAE. Methods Male C57BL/6 mice...
Inflammation and lipid accumulation are key events in atherosclerosis progression. Despite arsenic trioxide's (ATO) toxicity, at appropriate doses, it is a useful treatment for various diseases treatment. ATO prevents vascular restenosis; however, its effects on atherosclerotic plaque development instability remain unclear. ApoE-/- mice were fed high-fat diet 4 months, starting the third month, was intravenously administered every other day. Atherosclerotic lesion size, histological...
Objective: Few epidemiological studies concentrated on dietary carotenoids and hypertension since new guideline released in 2017. Thus, this study was aimed to evaluate their association. Methods: Data from National Health Nutrition Examination Survey (NHANES) 2007–2014 were used cross-sectional study. Dietary data obtained 24-h recall interviews. Hypertension defined as SBP at least 130 mmHg or DBP 80 mmHg, taking antihypertensive medicine self-report. Logistic regression models restricted...
There is scant evidence on a relationship between metabolic acid load and acute myocardial infarction (AMI). We evaluated the serum albumin corrected anion gap (ACAG), biomarker, post-myocardial heart failure (post-MI HF) in patients with AMI.This prospective, single-center study enrolled 3,889 AMI. The primary endpoint was incidence of post-MI HF. Serum ACAG levels were calculated following formula: = AG + (40 - [albuminemia g/l]) × 0.25.After correction for multiple confounding factors,...
Background Self-management interventions empower individuals to manage their chronic conditions and daily life after stroke. However, traditional in-person self-management often face transportation geographical barriers. Digital may offer a solution address this gap.
Background: The use of peripherally inserted central catheters (PICC) in neonates has been established for numerous years, with significant advancements and enhancements observed PICC technology over time. objective this study is to investigate the application trend a 10-year period single-center neonatal intensive care unit (NICU). Methodology: A retrospective analysis was conducted on infants admitted between January 2012 October 2021 who underwent catheterization. Data pertaining...
BACKGROUND: Early identification of out-of-hospital high-risk sudden cardiac death (SCD) after acute myocardial infarction is crucial for timely therapeutic interventions. However, left ventricular ejection fraction as a standalone clinical stratification tool has major limitations, necessitating improved risk strategies. METHODS: Mass spectrometry measured 6592 peptides and 522 proteins, from which targeted proteomics identified the optimal protein combination to assess SCD risk. ELISA...
Purpose: Previous studies have reported mixed results regarding the importance of cortical abnormalities in patients with migraines. However, sulci, as a component cerebral cortex, not been specifically investigated migraine patients. Therefore, we aim to evaluate alterations sulcal morphology among chronic (CM), episodic (EM), and healthy controls (HCs). Patients Methods: In this cross-sectional study, structural magnetic resonance images were acquired from 35 CM, EM, HCs. Cortical sulci...
Cellular behavior is strongly influenced by the architecture and pattern of its interfacing extracellular matrix (ECM). For an artificial culture system which could eventually benefit translation scientific findings into therapeutic development, should capture key characteristics a physiological microenvironment. At same time, it also enable standardized, high throughput data acquisition. Since ECM composed different fibrous proteins, studying cellular interaction with individual fibrils...
Cellular autoimmune responses, especially those mediated by T-cells, play vital roles in the immunopathogenesis of dilated cardiomyopathy (DCM). Metabolic reprogramming directly controls T-cell function, imprinting distinct functional fates. However, its contribution to dysfunction and DCM is unknown. Here, we found that patients, CD4+ T-cells exhibited immune glycolytic metabolic based on extracellular acidification oxygen consumption rates. Similar results were observed splenic cardiac...
Abstract Solution‐based near‐field electrospinning is employed to construct polymeric network membranes, made of orderly arranged and interconnected fibers. The narrow tip‐to‐nozzle separation the direct‐writing process leads solvent enriched fibers being deposited on substrate, despite use a low boiling point solvent. This results in with cross‐sectional aspect ratio (flattened appearance), but providing unique opportunity produce fiber junctions through situ, localized etching by...
Background Currently, studies have shown that anti-CGRP monoclonal antibodies are effective drugs for the prophylaxis and treatment of episodic migraine. Therefore, first time, we classified concluded 10 regimens according to different doses, drugs, routes administration, courses treatment, so as provide a reference further clinical studies.Methods We studied relevant randomized controlled trials (RCTs) published before August 2020 on PubMed, Embase, Ovid MEDLINE, Web Science, Cochrane...
Considerable studies have given convincing evidence of a forefront position for vascular aging in preventing cardiovascular disease. Various functions Long non-coding RNAs (lncRNAs) are becoming increasingly distinct aging-related diseases. This study aims at better insight into the expression profile and mechanisms lncRNAs senescence. High-throughput sequencing was used to detect differential (DE) mRNAs aorta 96 W 8 W-old mice, while 1423 80 were differentially expressed. By performing GO...