Holly Baker‐Rand

ORCID: 0009-0005-9301-6929
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About
Contact & Profiles
Research Areas
  • Endometrial and Cervical Cancer Treatments
  • Ovarian cancer diagnosis and treatment
  • Nutrition and Health in Aging
  • Cervical Cancer and HPV Research
  • Frailty in Older Adults
  • Testicular diseases and treatments
  • Grief, Bereavement, and Mental Health
  • Endometriosis Research and Treatment
  • Menopause: Health Impacts and Treatments
  • Muscle and Compartmental Disorders
  • Acute Kidney Injury Research
  • Hip and Femur Fractures
  • Reproductive System and Pregnancy
  • Healthcare innovation and challenges
  • Polyomavirus and related diseases
  • Palliative Care and End-of-Life Issues

University of Manchester
2024-2025

Taunton & Somerset NHS Foundation Trust
2025

Cancer Research UK Manchester Institute
2025

Musgrove Park Hospital
2024

NIHR Manchester Biomedical Research Centre
2024

Royal Devon & Exeter NHS Foundation Trust
2021-2022

Endometrial cancer is the sixth commonest in women worldwide, with over 417,000 diagnoses 2020. The disease incidence has increased by 132% last 30 years and set to continue rise response an ageing population increasing global rates of obesity diabetes. A greater understanding mechanisms driving endometrial carcinogenesis led identification potential strategies for primary prevention, although prospective evaluation their efficacy within clinical trials still awaited. early diagnosis...

10.3390/cancers16051028 article EN Cancers 2024-03-01

Summary We report a case of small cell carcinoma the ovary, hypercalcaemic type, rare and aggressive form ovarian cancer, causing an acute kidney injury. A woman in her mid-30s presented with large pelvic mass abdominal distention, this was associated rapidly deteriorating renal function, which did not improve standardised injury treatment. There high suspicion cancer. She deteriorated underwent emergency cytoreductive surgery, followed by systemic chemotherapy. Her presentation, electrolyte...

10.1136/bcr-2024-262687 article EN BMJ Case Reports 2025-01-01

These guidelines have been developed jointly by the British Gynaecological Cancer Society and Menopause to provide information for all healthcare professionals managing women treated gynaecological cancer. Menopausal symptoms can a significant impact on quality of life women. therapies, including surgery, pelvic radiotherapy, chemotherapy endocrine therapy, affect ovarian function. The benefits risks using hormone replacement therapy are considered cancer type with guidance HRT optimal time...

10.1177/20533691241286666 article EN Post Reproductive Health 2024-10-11

10.1111/tog.12922 article EN The Obstetrician & Gynaecologist 2024-04-01

Abstract Introduction Cervical screening rates in the UK are falling, limiting our ability to prevent cervical cancer. Peak incidence of cancer coincides with average age childbirth and women young children less likely be screened. Current guidelines advise waiting 12-weeks after delivery perform screening, but this recommendation is not based on evidence from era liquid-based cytology (LBC) or high-risk Human Papilloma Virus (hrHPV) testing. New mums suggested that could offered at 6-weeks...

10.1101/2024.11.20.24317620 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2024-11-20

Frailty has been associated with worse cancer-related outcomes for people gynecological cancers. However, the lack of clear guidance on how to assess and modify frailty prior instigating active treatments potential lead large variations in practice outcomes. This study aimed evaluate current perspectives healthcare practitioners provision care patients a cancer.Data were collected via questionnaire-based survey distributed by Audit Research Gynecological Oncology (ARGO) collaborative...

10.1136/ijgc-2022-003396 article EN cc-by-nc-nd International Journal of Gynecological Cancer 2022-05-09

Key content Nonepithelial ovarian cancers (NEOCs) are rare forms of cancer, including malignant germ cell tumours (MOGCTs), sex cord‐stromal (SCSTs) and sarcoma. Tumour markers alpha‐fetoprotein, human chorionic gonadotrophin, lactate dehydrogenase inhibin can be useful in aiding preoperative diagnosis masses. NEOCs staged using a similar classification to epithelial tumours; however, the staging system for male is considered more prognostic tool. These occur at any age; many present...

10.1111/tog.12755 article EN The Obstetrician & Gynaecologist 2021-06-07
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