A5009142568- Tryptophan and brain disorders
- Stress Responses and Cortisol
- Sleep and related disorders
- Neurotransmitter Receptor Influence on Behavior
- Sleep and Wakefulness Research
- Neuropeptides and Animal Physiology
- Alcoholism and Thiamine Deficiency
- Distributed Sensor Networks and Detection Algorithms
- Wireless Communication Security Techniques
- Substance Abuse Treatment and Outcomes
- Resilience and Mental Health
- COVID-19 and Mental Health
- Child and Adolescent Psychosocial and Emotional Development
- Psychosomatic Disorders and Their Treatments
- interferon and immune responses
- Inflammasome and immune disorders
- Sparse and Compressive Sensing Techniques
- Attention Deficit Hyperactivity Disorder
- Long-Term Effects of COVID-19
- Alzheimer's disease research and treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Adipose Tissue and Metabolism
- Mental Health Research Topics
- Biochemical effects in animals
- Suicide and Self-Harm Studies
Dalian University
2025
Zhejiang University
2024
Beijing University of Chinese Medicine
2022-2024
Hangzhou Seventh Peoples Hospital
2024
Wenzhou Medical University
2020-2023
McMaster University
2022
Jinzhou Kangning Hospital
2020
University of Chinese Academy of Sciences
2020
Zhejiang Chinese Medical University
2017
Affiliated Hospital of Guilin Medical College
2014
Neuroinflammation plays a crucial role in the pathogenesis and progression of Alzheimer's disease (AD). The Sterile Alpha Toll Interleukin Receptor Motif-containing protein 1 (SARM1) has been shown to promote axonal degeneration is involved neuroinflammation. However, SARM1 AD remains unclear. In this study, we found that was reduced hippocampal neurons model mice. Interestingly, conditional knockout (CKO) central nervous system (CNS, SARM1<sup>Nestin</sup>-CKO mice) delayed cognitive...
Major depressive disorder is an ordinary mental disorder, and suicide considered to be a major concern among patients with MDD. Previous studies focused on the relationship between attempts metabolism in elderly MDD, while ignore young people. The aim of this study find potential MDD way prevent ultimately reduce MDD.Cross-sectional design was employed study.740 aged 18 45 years old had been consecutively recruited 2011 2017, 128 whom attempts. Their serum samples used monitor fasting blood...
Abstract Viral pneumonia is a common complication caused by Influenza A virus infection and characterized severe pulmonary inflammation. previous study showed that berberine (BBR) significantly ameliorated the inflammation in mice with influenza viral but its underlying mechanism not entirely understood. In this study, we reproduced mouse model of through intranasal A/Puerto Rico/8/34 (H1N1), to further investigate anti‐inflammatory BBR based on nucleotide‐binding oligomerization domain‐like...
Abstract Background Suicidal ideation is common among people diagnosed with schizophrenia spectrum disorders and may be related to neurocognitive, social cognitive, clinical variables. This study aimed investigate the relationships between suicidal both neurocognitive function empathy. Methods The sample for this cross-sectional comprised 301 schizophrenic patients aged 18–44 years. All participants were administered Beck Scale Suicide Ideation—Chinese Version (BSI—CV), Repeatable Battery...
Human pose estimation is a challenging task in computer vision. Most algorithms perform well regular scenes, but lack good performance occlusion scenarios. Therefore, we propose multi-type feature fusion network based on importance weighting, which consists of three modules. In the first module, multi-resolution backbone with two enhancement sub-modules, can extract features from different scales and enhance expression ability. second expressiveness keypoint by suppressing obstacle...
This study aimed to evaluate the efficacy of high-frequency repetitive transcranial magnetic stimulation (rTMS) over left dorsolateral pre-frontal cortex (DLPFC) in ameliorating negative symptoms and cognitive impairments patients with chronic schizophrenia. Fifty-two schizophrenia were randomly assigned two groups: active rTMS group sham group, existing antipsychotic drugs combined 20 sessions 10 Hz active/sham DLPFC (20 min/session, 5 times/week). The PANSS, RBANS, SCWT used clinical...
The COVID-19 is a highly contagious disease belonging to the family of coronaviruses which can affect great deal people shortly. As devastating event in world, many suffer PTSD from this severe disease. aim study explore prevalence and severity post-traumatic stress disorder (PTSD) symptoms, discuss possible factors among general public China after epidemic outbreak.This cross-sectional study. We used self-designed demographic questionnaire Posttraumatic Stress Checklist-Civilian Version...
Abstract Autism spectrum disorder (ASD), a group of neurodevelopmental diseases, is characterized by social deficits, communication difficulties, and repetitive behaviors. Sterile alpha TIR motif-containing 1 protein (SARM1) known as an autism-associated enriched in brain tissue. Moreover, SARM1 knockdown mice exhibit autism-like However, its specific mechanism ASD pathogenesis remains unclear. Here we generated parvalbumin-positive interneurons (PVI)-specific conditional knockout (SARM1 PV...
The potential correlation between serum lipid profiles and suicidal tendencies has been previously reported, however, it is unclear whether have definite relevance to recently attempted suicides in individuals suffering from major depressive disorder (MDD). In this study, the relationship blood lipids suicide attempts first-episode MDD patients research were used examine there a connection. cross-sectional study recruited 580 at time of their first episode, measuring up diagnostic standard...
Most women in the perinatal period face sleep issues, which can affect their mental health. Only a few studies have focused on trajectories and depressive symptoms of during China. This study aims to explore development trajectory quality by classifying pregnant according changes pregnancy postpartum investigate correlation between different groups symptoms. The Pittsburgh Sleep Quality Index (PSQI) was used assess quality, Edinburgh Postnatal Depression Scale (EPDS) depression. Participants...
Methamphetamine (METH) dependence is a complex and dynamic public health problem. Long-term abuse of METH can increase numerous risks mental physical problems. Currently, the methods to reduce improve withdrawal symptoms are limited ineffective. Resilience seen as multidimensional capability recover or bounce back from stressful events also generally considered protective factor against dysfunction.One hundred thirty-four males with were consecutively recruited Huanglong Compulsory Isolated...
Background Sleep disorders are prevalent among patients with schizophrenia and associated several negative consequences. Although, researchers have recently suggested that sleep a close correlation alexithymia, also has strong there been few studies on the relationships between schizophrenia, alexithymia. Therefore, this study aimed to explore psychiatric symptoms, alexithymia problems in so as provide reference for clinical treatment of comorbidity. Methods In total, 977 were recruited...
Objective: Alcohol use disorder (AUD) is the most common substance disorder, which may relate to increased impulsivity. A more detailed understanding of potential moderating factor on association between AUD and impulsivity likely have far-reaching effects. This study aims examine whether interaction a genetic variant ZNF804A rs1344706 alcohol related in Chinese Han adult males diagnosed with AUD. Methods: total 455 were included this study. Impulsivity was assessed using Barratt...
Background Previous studies suggest that alcohol dependence is associated with depression, however, the effect of varies from individual to individual, which may be due different genetic backgrounds. The interactions between and gene polymorphisms finally shape onset depression. Neuropeptide Y (NPY), can maintain homeostasis high-stress stimulation, protect individuals Here, we explored whether NPY rs16147:T &gt; C has an association depression in during period withdrawal. Methods A...
<title>Abstract</title> Post-traumatic stress disorder (PTSD) is one of the most serious and harmful stress-related emotion disorders caused by traumatic experiences. Upregulation autophagy flux in neuronal cells has been believed to play a pivotal role pathogenesis PTSD, however, effect upregulated on PTSD based specific brain regions not fully investigated. In our study, inhibition amygdala rather than mPFC WT mice alleviated anxiety-like behaviors modeling. Our results also suggested that...
Abstract Backgrounds: Major depressive disorder is an ordinary mental disorder, suicide and physical health deterioration are two major sequelae. Some studies indicate that metabolic levels associated with attempt. Previous have focused on the relationship between attempts metabolism in elderly patients MDD, while ignore young people. The aim of this study to find potential MDD a promising way effectively prevent ultimately reduce patients. Methods: Cross-sectional design was employed...
Abstract Background Methamphetamine (METH) dependence is a complex and dynamic public health problem. Long-term abuse of METH can increase numerous risks mental physical problems. Currently, the methods to reduce improve withdrawal symptoms are limited ineffective. Resilience regarded as an individuals’ protective moderator against stress may play role in stress-related diseases. Methods One hundred twelve males with were consecutively recruited from Huanglong Compulsory Isolated...
In this paper, we consider a distributed lossy compression network with <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$L$</tex> encoders and decoder. Each encoder observes source sends compressed version to the The decoder produces joint reconstruction of target signals mean squared error distortion below given threshold. It is assumed that observed sources can be expressed as sum corruptive noises which are independently generated from two...
AIDS is one of the most serious infections in world. The HIV-1 displays powerful evasion from human immune system that causes great difficulty clinical treatment. Researchers try to develop different treatment ways prevent duplication. Except for drug treatment, antibody therapy and bioengineering technology have been developed rapidly. novel studies at home abroad are reviewed this article. Key words: Acquired immunodeficiency syndrome; Broadly neutralizing antibodies; TFC; CRISPR/Cas9
Abstract Background: Impulsivity and depression are considered to have a crucial role in the process of Methamphetamine dependence withdrawal. However, little is known about underlying factors that influence relationship users. Previous studies indicated fatigue was present variety neurological diseases tended increase during late Thus, this study aimed explore whether takes part mediating association between impulsivity depression. Methods: 112 users withdrawal period were recruited from...