A5101872558- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Crystallography and molecular interactions
- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- Orthodontics and Dentofacial Orthopedics
- Luminescence Properties of Advanced Materials
- Chromosomal and Genetic Variations
- Acute Myeloid Leukemia Research
- Epilepsy research and treatment
- MicroRNA in disease regulation
- Neurobiology and Insect Physiology Research
- Cancer-related gene regulation
- Metal-Organic Frameworks: Synthesis and Applications
- Insect and Arachnid Ecology and Behavior
- Microwave Dielectric Ceramics Synthesis
- Advanced Nanomaterials in Catalysis
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Infectious Encephalopathies and Encephalitis
- Streptococcal Infections and Treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- Bacterial biofilms and quorum sensing
- Erythrocyte Function and Pathophysiology
- Covalent Organic Framework Applications
- Esophageal Cancer Research and Treatment
First Affiliated Hospital of GuangXi Medical University
2016-2025
Guangxi Medical University
2014-2025
Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University
2019-2025
Wenzhou Medical University
2014-2025
Guangxi University
2023
Guangxi University of Chinese Medicine
2023
Sun Yat-sen University
2018-2022
Stomatological Hospital of Chongqing Medical University
2022
Chongqing Medical University
2022
Central South University
2015-2021
Solvothermal reactions of 5-(4-pyridyl)-isophthalic acid (H2pbdc) and transition-metal centers (Ni2+/Co2+/Zn2+) in the presence (or absence) N-auxiliary 4,4′-bis(1-imidazolyl)biphenyl (bimb) ligand produce [Ni2(pbdc)2(μ2-H2O)(H2O)2·(DMA)2.7]n (DMA = N,N′-dimethylacetamide, 1), [Ni12(pbdc)12(μ2-H2O)6(py)2(H2O)8(DMA)2·(H2O)5·(DMA)9]n (2), [Co2(pbdc)2(bimb)2·(bimb)0.5·(H2O)4·(DMF)0.25]n (3) [Zn(pbdc)(bimb)·(H2O)]n (4), which exhibit structural diversity. Both compounds 1 2 display a uninodal...
Three metal–organic frameworks (MOFs) [M2(d-cam)2(bimb)2]n·3.5nH2O (M = Mn for 1, Co 2) and [Cd8(d-cam)8(bimb)4]n (3) (d-H2cam d-camphor acid, bimb 4,4′-bis(1-imidazolyl)biphenyl), solvothermally synthesized, exhibit structural diversity. The charming aspect of these is that compound 3 the very first MOF-based sensor quantitatively detecting three different types analytes (metal ions, aromatic molecules, pesticides). And also, both compounds 2 show rapid uptake ready regeneration methyl...
Iron overload is one of the main factors that increase morbidity and mortality in patients with non-transfusion dependent thalassemia (NTDT).This study aimed at investigating prevalence severity iron Chinese NTDT patients.we analyzed serum ferritin (SF), liver concentration (LIC) cardiac T2* 178 this cross-sectional study.The median SF level was 996.00(27.15-19704.00) ng/ml LIC value 8.90(0.60-43.00) mg Fe/g dry weight (dw). The youngest patient 5 years old 5.6 dw LIC. 33.06(7.46-75.08) ms....
BACKGROUND RUNXl plays a key regulatory role in the process of hematopoiesis and is common target for multiple chromosomal translocations human acute leukemia. Mutations RUNX1 gene can lead to leukemia affect prognosis AML patients. We aimed identify pivotal genes pathways involved RUNX1-mutated patients with myeloid (AML) explore possible molecular markers novel therapeutic targets disease. MATERIAL AND METHODS The RNA sequencing datasets 151 cases were obtained from Cancer Genome Atlas...
The prevalence of de novo coding genes is controversial due to length and constraints. Noncoding genes, especially small ones, are freer evolve by comparison. best examples microRNAs (miRNAs), a large class regulatory molecules ∼22 nt in length. Here, we study six miRNAs Drosophila, which, like most new testis-specific. We ask how why die because gene death must be sufficiently frequent balance the many births. By knocking out each miRNA gene, analyzed their contributions nine components...
Abstract Tumor immune cell infiltration was significantly correlated with the progression and effect of immunotherapy in cancers including esophageal carcinoma (ESCA). However, no biomarkers were identified which associated ESCA. In present study, a total 128 common differentially expressed genes (DEGs) between squamous carcinomas (ESCC) adenocarcinomas (EAC). The results gene ontology (GO) enrichment Reactome pathway analysis displayed that up-regulated DEGs mainly involved regulation...
This cross-sectional research evaluated the morphological characteristics of alveolar bone in skeletal class II open-bite individuals compared to and I non-open-bite individuals. A sample 82 patients (all were cervical vertebral stage 6) was divided into three groups (class OB group, n = 29; NOB 24) according bilateral molar relationship, ANB angle, anterior overbite measured by cephalometric analysis. The evaluation performed with specialized software (Mimics 21.0) initial cone-beam...
In coronavirus disease 2019 (COVID-19) patients, interleukin (IL)-6 is one of the leading factors causing death through cytokine release syndrome. Hence, identification IL-6 downstream from clinical patients' transcriptome very valid for analyses its mechanism. However, study conditional and time consuming to collect optional size samples, as patients have heterogeneity. A possible solution deeply mine relative existing data. Several transcriptome-based studies on other diseases or...
Hb Southampton [β106(G8)Leu→Pro; HBB: c.320T>C] is a rare, unstable hemoglobin (Hb), variant. The main clinical presentation of this variant hemolytic anemia. We detected mutation in 2-year-old Chinese girl with history regular transfusions. To the best our knowledge, first time that has been found Asian population.
Non-alcoholic fatty liver disease (NAFLD) has become a common health issue worldwide, and P-element-induced wimpy testis (PIWI)‑interacting RNAs (piRNAs) have been shown to be differentially expressed in variety of diseases. The aim the present study was investigate potential relationship between piRNA NAFLD. A NAFLD mouse model established using methionine‑ choline‑deficient (MCD) diet choline‑sufficient (MCS) diet. Following this, tissues were removed stained with hematoxylin eosin, levels...
The aim of the present study was to identify potential molecular mechanisms and therapeutic targets in regards isocitrate dehydrogenase 2 (IDH2) R140Q-mutated acute myeloid leukemia (AML). An RNA sequencing dataset IDH2 wild-type adult de novo AML bone marrow samples obtained from Cancer Genome Atlas (TCGA) database. edgeR package used screen for differentially expressed genes (DEGs), were identified using Database Annotation, Visualization, Integrated Discovery (DAVID) v6.8, Biological...
Maternofetal carnitine transport through the placenta is main route of fetal uptake. Decreased free levels discovered by newborn screening has identified many asymptomatic adult women with systemic primary deficiency (PCD). Here, we presented amplitude integrated electroencephalogram (aEEG) and magnetic resonance imaging (MRI) findings from a neonate epilepsy whose mother was deficient. A one-day-old female admitted after experiencing seizures for half day; status epilepticus found on...
Abstract Due to extensive pleiotropy, trans-acting elements are often thought be evolutionarily constrained. While the impact of on gene expression evolution has been extensively studied, relatively little is understood about contribution a single trans regulator interspecific and phenotypic divergence. Here, we disentangle effects genomic context miR-983, an adaptively evolving young microRNA, divergence between Drosophila melanogaster D. simulans. We show miR-983 promote in testis despite...
Objective While low-dose lamotrigine has shown effectiveness in managing paroxysmal kinesigenic dyskinesia (PKD) pediatric populations, the cognitive consequences of extended use are yet to be fully elucidated. This study seeks assess evolution functions and amelioration attention deficit hyperactivity disorder (ADHD) symptoms following a two-year treatment children. Methods investigation employed an open-label, uncontrolled trial design. Between January 2008 December 2021, thirty-one...