- Phytochemicals and Antioxidant Activities
- Mycotoxins in Agriculture and Food
- Microencapsulation and Drying Processes
- Fermentation and Sensory Analysis
- Tea Polyphenols and Effects
- Botanical Studies and Applications
- Ginseng Biological Effects and Applications
- Pharmacological Effects of Natural Compounds
- Proteins in Food Systems
- Fungal Biology and Applications
- Cardiovascular Effects of Exercise
- Cerebrovascular and Carotid Artery Diseases
- Cancer, Lipids, and Metabolism
- Neurological Disease Mechanisms and Treatments
- Wheat and Barley Genetics and Pathology
- Listeria monocytogenes in Food Safety
- Spine and Intervertebral Disc Pathology
- Polysaccharides Composition and Applications
- Facial Nerve Paralysis Treatment and Research
- Natural product bioactivities and synthesis
- Heterotopic Ossification and Related Conditions
- Nanocomposite Films for Food Packaging
- Plant and fungal interactions
- Lower Extremity Biomechanics and Pathologies
- Bone Metabolism and Diseases
Yantai University
2013-2024
Guangxi Academy of Sciences
2024
The People's Hospital of Guangxi Zhuang Autonomous Region
2023
Tongji University
2017
Riverside Hospital of Guangxi Zhuang Autonomous Region
2017
Wenzhou Medical University
2011-2015
First Affiliated Hospital of Wenzhou Medical University
2015
Jiangsu Cancer Hospital
2004
20(S)-ginsenoside-Rg3 (C42H72O13), a natural triterpenoid saponin, is extracted from red ginseng. The increasing use of 20(S)-ginsenoside Rg3 has raised product safety concerns.In acute toxicity, was singly and orally administrated to Kunming mice Sprague-Dawley (SD) rats at the maximum doses 1600 mg/kg 800 mg/kg, respectively. In 26-week toxicity study, we used repeated oral administration in SD over 26 weeks 0, 20, 60, or 180 mg/kg. Moreover, 4-week recovery period scheduled observe...
<h3>Objective</h3> HBV has two forms of genomic DNA, relaxed-circular DNA (rcDNA) and duplex-linear (dlDNA). Compared to rcDNA, dlDNA been demonstrated integrate more frequently into host cellular chromosomes, which may have oncogenic consequences. However, the proportion relative total its clinical significance in patients remain be investigated. <h3>Design</h3> Based on structural difference between rcDNA dlDNA, we developed a peptide nucleic acid (PNA)-mediated quantitative real-time PCR...
DEDEQIPSHPPR, the calcium-binding peptide (CBP) identified in soy yogurt, was proven to be a potential cofactor osteoporosis prevention our previous study, but mechanism unknown. In this activity of alkaline phosphatase (ALP) and osteocalcin (OCN), regulation RUNX2, expression TβRI were investigated elucidate underlying mechanism. The results show that CBP upregulated ALP OCN concentration increased RUNX2 activation MAPK signaling pathway. Similarly, osteogenesis-related genes osteoblasts...
A polyethylene glycol-poly(ε-benzyloxycarbonyl-l-lysine) (PEG-SS-PLL) block copolymer based on a disulfide-linked, novel biodegradable catiomer bearing PEG-sheddable shell was developed to avoid "PEG dilemma" in nanoparticle intracellular tracking of PEG-PLL where PEG nondegradable. However, PEG-SS-PLL catiomers have not been used deliver small interfering VEGF RNA (siVEGF) antiangiogenesis gene therapy. In this study, we aimed investigate whether can siVEGF into cancer cells and at the same...
Abstract BACKGROUND T‐2 toxin is a widely distributed mycotoxin in cereals. HT ‐2 the major metabolite, which also contaminant and have been identified as having carcinogenic, hepatotoxic, teratogenic immunotoxic properties. To reduce risk of contamination, rapid, highly sensitive inexpensive assay for detection required. RESULTS In this study high‐sensitivity chemiluminescent enzyme‐linked immunoassay ( CL‐ELISA ) was developed. With help substrate, protocol showed character with an IC 50...
Summary To assess prefrontal brain network abnormality in adults with obstructive sleep apnea (OSA), resting‐state functional near infrared spectroscopy (rs‐fNIRS) was used to evaluate 52 subjects, including 27 OSA and 25 healthy controls (HC). The study found that patients had a decreased connection edge number, particularly the between right medial frontal cortex (MFG‐R) other right‐hemisphere regions. Graph‐based analysis also revealed lower global efficiency, local clustering coefficient...
Response surface methodology was used to optimize the ultrasonic-assisted extraction conditions for aflatoxin B1 in peanuts. Box–Behnken center composite optimization performed with factors including ratio of sample extractant, sonication time, and temperature. three levels determine prime on B1. High-performance liquid chromatography fluorescence detector determination The optimum were 1 g peanuts 86 mL a time 7 min, temperature 73°C. mean recoveries fortified between 87.6 93.5% an interday...
In order to investigated current occurrence of major mycotoxins in dietary kelp Shandong Province Northern China, a reliable, sensitive, and rapid liquid chromatography tandem mass spectrometry (LC-MS/MS) method was developed validated for simultaneous determination the 7 most frequent mycotoxins, including 3-acetoxy deoxynivalenol (3AcDON), 15-acetoxy (15AcDON), Deoxynivalenol (DON), Fusarenon-X (F-X), Nivalenol (NIV), T-2 toxin (T-2), Zearalenone (ZEA). Based on optimized pretreatment...
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Objective: This review was designed to summarize the pathogenesis, clinical manifestations and current progress in treatment of cervical spondylotic radiculopathy (CSR), so as provide clinicians with a comprehensive understanding CSR reference for strategies. Method: A search conducted across multiple databases, including PubMed (https://pubmed.ncbi.nlm.nih.gov/), Embase (https://www.embase.com/search/), Web Science (https://www.webofscience.com), Direct (https://www.sciencedirect.com/),...