A5025555281- Venous Thromboembolism Diagnosis and Management
- Cancer Immunotherapy and Biomarkers
- Central Venous Catheters and Hemodialysis
- Inflammatory Biomarkers in Disease Prognosis
- Cardiac tumors and thrombi
- Atrial Fibrillation Management and Outcomes
- Colorectal and Anal Carcinomas
- Head and Neck Cancer Studies
- Lung Cancer Treatments and Mutations
- Gastric Cancer Management and Outcomes
- Lung Cancer Research Studies
- COVID-19 Clinical Research Studies
- Radiomics and Machine Learning in Medical Imaging
- Cancer, Lipids, and Metabolism
- Lymphoma Diagnosis and Treatment
- Acute Myocardial Infarction Research
- Neuroendocrine Tumor Research Advances
- Multiple and Secondary Primary Cancers
- COVID-19 and healthcare impacts
- Chronic Lymphocytic Leukemia Research
- Cancer Diagnosis and Treatment
- Colorectal Cancer Treatments and Studies
- Prostate Cancer Treatment and Research
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Metabolomics and Mass Spectrometry Studies
Spanish Society of Hematology and Hemotherapy
2022-2024
Complejo Hospitalario de Jaén
2017-2023
Hospital Costa del Sol
2023
Abstract Purpose Immune Checkpoint Inhibitors (ICI) can be associated with thrombotic events, both venous and arterial (VTE/AT). However, there is a paucity of information regarding patients in routine clinical practice. Methods/patients Retrospective, multicenter study promoted by the Thrombosis Cancer Section Spanish Society Medical Oncology (SEOM). Patients melanoma lung cancer who initiated ICI between 01/01/2015 31/12/2019 were recruited. Minimum follow-up was 6 months (unless it not...
Both venous and arterial thrombotic events (VTE/AT) can be associated with Immune Checkpoint Inhibitors (ICI). However, there is a paucity of information apropos patients in routine clinical practice.
Both venous and arterial thrombotic events (VTE/AT) can be associated with immune checkpoint inhibitors (ICI). However, there is a paucity of information apropos patients in routine clinical practice.Retrospective, multicenter study promoted by the Thrombosis Cancer Section Spanish Society Medical Oncology (SEOM). Individuals kidney or bladder cancer who initiated ICI between 01/01/2015 12/31/2020 were recruited. Minimum follow-up was 6 months (except cases demise). The primary objective to...
This study examined the real-world use of nivolumab in patients with recurrent/metastatic squamous cell carcinoma head and neck (R/M SCCHN). was a multinational retrospective (VOLUME) assessing treatment effectiveness safety outcomes prospective (VOLUME-PRO) HRQoL patient-reported symptoms. There were 447 51 VOLUME VOLUME-PRO, respectively. Across both studies, median age 64.0 years, 80.9% male, 52.6% former smokers. Clinical interest included overall survival (rwOS) progression-free...
Introduction There is currently no validated score capable of classifying cancer-associated pulmonary embolism (PE) in its full spectrum severity. This study has the EPIPHANY Index, a new tool to predict serious complications cancer patients with suspected or unsuspected PE. Method The PERSEO Study prospectively recruited individuals PE and active receiving antineoplastic therapy from 22 Spanish hospitals. estimation relative frequency θ based on Index categories was made using Bayesian...
Abstract Purpose The CoVID-TE model was developed with the aim of predicting venous thrombotic events (VTE) in cancer patients Sars-Cov-2 infection. Moreover, it capable hemorrhage and mortality 30 days following infection diagnosis. is pending validation. Methods/patients Multicenter retrospective study (10 centers). Adult active oncologic disease/ antineoplastic therapy hospitalized between March 1, 2020 1. 2022 were recruited. primary endpoint to association risk categories occurrence...
We present the case of a 45-year-old man with locally advanced lung adenocarcinoma diagnosed deep vein thrombosis and synchronous pulmonary embolism. After 6 months anticoagulant treatment low molecular weight heparin, dose was reduced to prophylactic levels new episode bilateral occurred. reintroducing heparin previous dose, patient suffered massive The authors conducted review evidence about beyond approach rethrombosis in anticoagulated patients.
e20080 Background: New classification of adenocarcinomas and better typing histological characteristics lung tumors leads us to wonder if these data could have a prognostic repercussion in the NSCLC who were into curative intent surgery Methods: We followed 95 patients with stage I-III underwent 4 year period (2010-2013), until August 2016. Most male (82%), smokers (90%, 44% exsmokers 56% active , median age at diagnosis was 64 years, 47% had previous COPD, 52% diagnosed without any symptom...
e15504 Background: Perioperative chemotherapy (QT) with platinum and fluoropyrimidines or without anthracyclines is recommended option in patients resectable gastric cancer (GC) at least cT2 nodal involvement. Another surgery followed by QT radiotherapy (QT/RT) RT D2 lymphadenectomy. Unfortunately, a considerable percentage of progress during neoadjuvant-QT (neo-QT) some cases become inoperable cancer. These could benefit from curative after diagnosis neo-QT. Currently,...
e20515 Background: It is known that outcome of patients included in clinical trials have a better than treated with standard therapy. This retrospective case-control study stage III and IV non-small cell lung cáncer (NSCLC) recruited vs advanced NSCLC usual practice our institution. Methods: We performed matching all participating chemotherapy and/or TKis (immunotherapy was not included) 5 year period (January 2010-November 2014) 1 st line setting, them ratio 1:2 individuals practice. There...
e23053 Background: Breast cancer (BC) is most common in women and development of new technologies for understanding molecular changes involved BC progression essential. Metabolic precede phenotypic changes, due to cellular regulation affects use small-molecule substrates cell division, growth or environmental such as hypoxia. Metabolomics (profiling metabolites biofluid, tissue) routinely applied a tool biomarker discovery. Liquid chromatography−mass spectrometry(LC−MS)is the dominating...
12085 Background: EPIPHANY is the first algorithm to predict serious complications in both suspected and unsuspected cancer-associated pulmonary embolism (PE), overcoming limitations of previous models. Methods: PERSEO a prospective multicenter study. We recruited cancer patients with incidental symptomatic PE treated between Oct. 2017 Dec. 2019. The primary aim was determine percentage at low predicted risk, least 3% accuracy. also compared predictive parameters other available scores for...
ABSTRACT Introduction There is currently no validated score capable of classifying cancer-associated pulmonary embolism (PE) in its full spectrum severity. This study has the EPIHANY Index, a new tool to predict serious complications cancer patients with suspected or unsuspected PE. Method The PERSEO Study prospectively recruited individuals PE and from 22 Spanish hospitals. estimation relative frequency θ based on EPIPHANY Index categories was made using Bayesian alternative for binomial...