Chang Cai

ORCID: 0009-0006-7036-1380
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About
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Research Areas
  • Functional Brain Connectivity Studies
  • Neurobiology of Language and Bilingualism
  • Neural dynamics and brain function
  • Action Observation and Synchronization
  • Stuttering Research and Treatment
  • Innovative Teaching and Learning Methods
  • Parkinson's Disease Mechanisms and Treatments
  • Lysosomal Storage Disorders Research
  • Neural Networks and Applications
  • EEG and Brain-Computer Interfaces
  • Speech Recognition and Synthesis
  • Phonetics and Phonology Research
  • Pregnancy and preeclampsia studies
  • Reading and Literacy Development
  • Hearing Impairment and Communication
  • Categorization, perception, and language
  • Digital Media and Visual Art
  • Online Learning and Analytics
  • Spatial Neglect and Hemispheric Dysfunction
  • Multisensory perception and integration
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Flow Measurement and Analysis
  • Optical Imaging and Spectroscopy Techniques
  • Electrical and Bioimpedance Tomography
  • Neuroscience and Music Perception

Advanced Telecommunications Research Institute International
2018-2025

National Center for Geriatrics and Gerontology
2022-2025

Central South University
2013-2024

Nanyang Technological University
2024

Central China Normal University
2024

Guangzhou Medical University
2008-2024

Xijing University
2023

Zhejiang Chinese Medical University
2022

University of California, San Francisco
2019-2021

Shanghai University
2005-2018

Background It is known that eyes-open (EO) and eyes-closed (EC) conditions invoke different organizations of brain functional networks, such as sensorimotor, attention, salience networks in healthy participants. Functional connectivity (FC) extracted from resting-state magnetic resonance imaging data, under either EO or EC conditions, has been widely applied to explore the neural substrates Alzheimer's disease (AD). However, impact eye on FC within AD continuum remains not fully understood....

10.1177/13872877241303849 article EN other-oa Journal of Alzheimer s Disease 2025-02-16

<title>Abstract</title> Current medications for schizophrenia (SCZ) remain ineffective, highlighting the growing need targeted treatments addressing abnormal brain states. Functional connectivities (FCs) in resting-state functional magnetic resonance imaging (rs-fMRI) have successfully identified states associated with both diagnosis and symptoms. These FC-based biomarkers been developed several neuropsychiatric disorders, including SCZ. Furthermore, neurofeedback training (FCNef) utilizing...

10.21203/rs.3.rs-6161823/v1 preprint EN cc-by Research Square (Research Square) 2025-03-20

Summary Background Exposure to allergens or air pollutants often leads asthma exacerbations associated with aggravation of airway inflammation. Although, repeated allergen challenge induces chronic allergic inflammation (CAAI) and remodelling, yet, the effects brief exposure such as SO 2 on development CAAI remodelling remain be clarified. Objective The aim experiment was investigate acute neutrophilic induced by subepithelial fibrosis (SEF) in a murine model asthma. Methods Acute 50 p.p.m....

10.1111/j.1365-2222.2008.03053.x article EN Clinical & Experimental Allergy 2008-07-09

In recent years, EEG microstate analysis has attracted much attention as a tool for characterizing the spatial and temporal dynamics of large-scale electrophysiological activities in human brain. Canonical 4 states (classes A, B, C, D) have been widely reported, they pointed out their relationships with cognitive functions several psychiatric disorders such schizophrenia, particular, through static parameters average duration, occurrence, coverage, transition probability. However, between...

10.1016/j.neuroimage.2022.119669 article EN cc-by-nc-nd NeuroImage 2022-10-04

Adaptively recalibrating motor-sensory asynchrony is critical for animals to perceive self-produced action consequences. It controversial whether motor- or sensory-related neural circuits recalibrate this asynchrony. By combining magnetoencephalography (MEG) and functional MRI (fMRI), we investigate the temporal changes in brain activities caused by repeated exposure a 150-ms delay inserted between button-press subsequent flash. We found that readiness potentials significantly shift later...

10.1016/j.neuroimage.2018.02.015 article EN cc-by-nc-nd NeuroImage 2018-02-08

Abstract Reality monitoring is defined as the ability to distinguish internally self-generated information from externally-derived information. The medial prefrontal cortex (mPFC) a key brain region subserving reality and has been shown be activated specifically during retrieval of However, it unclear if mPFC encoding into memory. If so, important understand whether successful critically depends on enhanced neural activity within initial this We used magnetoencephalographic imaging (MEGI)...

10.1038/s41598-019-43291-7 article EN cc-by Scientific Reports 2019-05-02

Abstract The importance of parathyroid glands (PGs) protection is increasingly recognized by thyroid surgeons in the field minimally invasive video-assisted thyroidectomy (MIVAT). However, current techniques for intra-operative identification and vascularity assessment PGs are contentious complex. This study presents design validation a miniaturized device fusion near-infrared autofluorescence (NIRAF) based on Raman spectroscopy laser speckle contrast imaging (LSCI) via an image algorithm...

10.1115/1.4065481 article EN Journal of Medical Devices 2024-05-07

Function segregation in the left inferior frontal gyrus was investigated a functional magnetic resonance imaging experiment using passive listening task, which Japanese volunteers were required to passively listen words and nonsense English. The statistical analysis results showed that dorsal part of more extensively activated by English than those Japanese, respectively, suggests automatic articulatory representation access for non-native stimuli perception, ventral either language, lexical...

10.1097/wnr.0b013e328010a07e article EN Neuroreport 2007-01-22

Previous studies have not determined whether the dorsal left inferior frontal gyrus has a lexical or semantic function. This study conducted an event-related functional MRI experiment to explore its function using Japanese words and nonsense in syllable counting task. The word task activated area (BA6/44) ventral (BA45/47) more extensively than did results indicate that also functions, despite it been related phonological processing from written stimuli. extensive activation by might result...

10.1097/wnr.0b013e32810f2de7 article EN Neuroreport 2007-06-22

The COVID-19 pandemic has led to an unprecedented shift towards online learning, compelling university students worldwide engage in self-directed learning within remote environments. Despite the increasing importance of education, factors driving students’ motivation for particularly those involving economic incentives, have not been thoroughly explored. This study aims address this gap by analyzing large-scale data collected from 19,023 across China during pandemic. Using mixed Bayesian...

10.3390/su16177330 article EN Sustainability 2024-08-26

10.1109/biocas61083.2024.10798242 article EN 2022 IEEE Biomedical Circuits and Systems Conference (BioCAS) 2024-10-24

The amplitude envelope of speech is crucial for accurate comprehension, and several studies have shown that the phase neural activity in theta-delta bands (1 - 10 Hz) tracks during listening, a process referred to as tracking. However, mechanisms underlying tracking been heavily debated. A dominant model posits reflects continuous entrainment endogenous low-frequency oscillations envelope. it has proven challenging distinguish this from alternative convolution evoked responses acoustic...

10.2139/ssrn.3787003 article EN SSRN Electronic Journal 2021-01-01

Abstract Background Excitation‐to‐inhibition (E/I) imbalance is believed to be a key contributor of synaptic and network degeneration in Alzheimer’s disease (AD)(Frere Slutsky, 2018). Extensive preclinical research on transgenic animal models AD have demonstrated neuronal circuit level E/I mediated by amyloid‐beta (Aβ) abnormally phosphorylated tau proteins (Harris et al., 2020; Palop Mucke, 2016). However, the mechanisms leading disrupted networks their relationships Aβ humans remain poorly...

10.1002/alz.055588 article EN Alzheimer s & Dementia 2021-12-01

Several problems in neuroimaging and beyond require inference on the parameters of multi-task sparse hierarchical regression models. Examples include M/EEG inverse problems, neural encoding models for task-based fMRI analyses, climate science. In these domains, both model to be inferred measurement noise may exhibit a complex spatio-temporal structure. Existing work either neglects temporal structure or leads computationally demanding schemes. Overcoming limitations, we devise novel flexible...

10.48550/arxiv.2111.01692 preprint EN cc-by-nc-nd arXiv (Cornell University) 2021-01-01

10.1250/ast.31.408 article EN Nippon Onkyo Gakkaishi/Acoustical science and technology/Nihon Onkyo Gakkaishi 2010-01-01

Abstract A number of studies have reported that the digit ratio 2D:4D (length second finger divided by length fourth finger) is smaller (longer digit) in autism spectrum disorder (ASD) than typically developed (TD) controls. Because form and function are closely related biological systems, we hypothesized 4D dominance occurs not only morphology but also physical performance ASD. Individuals with ASD TD controls participated a multi-digit force-producing task. showed significant dependence...

10.1038/s41598-018-38421-6 article EN cc-by Scientific Reports 2019-02-11

Fundamental frequency (F0) of our vocalization is regulated by auditory feedback. Manipulation F0 in the feedback invokes compensatory response vocalization, whose amplitude known to depend on task (singing or speaking; instruction follow/ignore heard pitch change) and averaged F0. In order exclude voluntary factor test if vocal register affected amplitude, we used a parametric modulation according maximal sequence [TAF, Kawahara (1992)] recovered an impulse with deconvolution during vowel...

10.1121/1.3249215 article EN The Journal of the Acoustical Society of America 2009-10-01
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