A5089804733- Palliative Care and End-of-Life Issues
- Cancer survivorship and care
- Childhood Cancer Survivors' Quality of Life
- Health Systems, Economic Evaluations, Quality of Life
- Mobile Health and mHealth Applications
- Telemedicine and Telehealth Implementation
- Pharmacology and Obesity Treatment
- Pathogenesis and Treatment of Hiccups
- Social Media in Health Education
- Cancer Immunotherapy and Biomarkers
- Health disparities and outcomes
- Nausea and vomiting management
- Anesthesia and Pain Management
- Patient Dignity and Privacy
- Peripheral Artery Disease Management
- Clinical practice guidelines implementation
- Safe Handling of Antineoplastic Drugs
- COVID-19 epidemiological studies
- Advanced Breast Cancer Therapies
- Diet and metabolism studies
- Food Security and Health in Diverse Populations
- SARS-CoV-2 and COVID-19 Research
- Family Support in Illness
- PARP inhibition in cancer therapy
- Family and Patient Care in Intensive Care Units
Institut Gustave Roussy
2021-2025
University of Glasgow
2024
Florida Institute of Technology
2024
Association of Research Libraries
2024
University of Hong Kong
2024
Université Paris-Saclay
2023
Chemotherapy associated with Immune Checkpoint Inhibitors is currently the standard of care in several tumor indications. This combination approach improves progression free survival (PFS), overall (OS) and complete pathological response (pCR) cancer types both early metastatic approaches. However, distinct spectrum toxicities between cytotoxic side effects immune related adverse events (irAEs) similar clinical presentations different management strategies remains a challenge daily practice...
PURPOSE Optimal comprehensive survivorship care is insufficiently delivered. To increase patient empowerment and maximize the uptake of multidisciplinary supportive strategies to serve all needs, we implemented a proactive pathway for patients with early breast cancer at end primary treatment phase. METHODS Pathway components included (1) personalized plan (SCP), (2) face-to-face education seminars consultation referrals (Transition Day), (3) mobile app delivering self-management advice, (4)...
1506 Background: SDOH are a significant driver of cancer care disparities impacting access to care, adherence treatment plans, treatment-related toxicities and quality life (QoL) across the continuum. RPM based on electronic patient-reported outcomes (ePROs) is powerful tool facilitate communication between pts providers, thereby improving symptom management, QoL disease outcomes. Equitable participation in pathways must be ensured avoid increase existing disparities. In this study we report...
12098 Background: France is currently in the midst of societal discussions concerning new legislation on active assistance dying. Continuous Deep Sedation Until Death (CDSUD) considered by some a “French exception” since 2016, but 8 years later, findings suggest that this procedure not really clear to all, including patients, their relatives and healthcare providers (HCP). The primary objective original research document psychological adjustment patients’ HCPs cancer context. Methods:...
<sec> <title>BACKGROUND</title> Background: Digital Remote Monitoring (DRM) is improving cancer care management. However, the determinants of its effectiveness, particularly role Nurse Navigators (NN) within these systems, still need to be explored. </sec> <title>OBJECTIVE</title> Objective: This study focuses on CAPRI DRM program, aiming fill gap in our understanding this specific system and effect patient oncology. <title>METHODS</title> Methods: The DRM, targeting patients oral anticancer...
Background The purpose of digital remote monitoring (DRM) is improving cancer care management. However, its effectiveness largely depends on the role nurse navigators (NNs) within these systems to process data and lead action. Objective This study aims fill gaps in our understanding NNs a specific system, drawing Cancérologie parcours région Ile-de-France (CAPRI) DRM program applied oncology patients. Methods CAPRI DRM, targeting patients taking oral anticancer agents, combines interfaces...
Abstract Background: Mobile health (mHealth) applications (app) and remote monitoring demonstrated tangible value in terms of improving dose delivery, quality life mitigating the severity acute treatment-related side effects, both metastatic setting during active phase treatment patients (pts) with early-stage solid tumors. However, mHealth ‘after primary treatment’ survivorship is less studied. Most BC pts have hormone receptor-positive disease are eligible for adjuvant ET 5-10 years....
Abstract Purpose: Non-adherence to adjuvant ET remains a major issue in patients with localized breast cancer (BC) and negatively impacts the long-term recurrence survival outcomes. Recently, we reported that 16.0% of premenopausal pts had serum tamoxifen level below set adherence threshold an increased their risk distant recurrences (NCT01993498). Thus, implementation personalized effective strategies improve topic active research. As approaches must rely upon comprehensive understanding...
Objective Phase I clinical trials usually include patients with advanced disease who have failed standard therapies and should benefit from early palliative care. We try to assess whether PALLIA 10, a score developed in France help identify might care referral, could be used phase department trial. Methods assessed 10 other prognostic factors enrolled at Gustave Roussy Cancer Center prospectively during two periods of time (cohort 1 (C1) 2 (C2)). A double-blind assessment the was done C2 by...
221 Background: Optimal comprehensive survivorship care, beyond screening of recurrences and new cancers, including health promotion, management physical as well psychosocial needs chronic conditions is insufficiently delivered. To increase patient (pt) empowerment maximize the uptake multidisciplinary strategies serving all needs, we implemented a proactive care pathway offered for pts with early BC at end their primary treatment phase (surgery, chemotherapy, radiotherapy). Methods: The...
Abstract Purpose Collegial Support Meetings (CSM) have been set up in the Gustave Roussy Cancer hospital for inpatients whose complex care requires a multi-professional approachinvolving participants from various fields. CSMs are composed not only of oncologists but also health-caregivers, member palliative team, an intensivist and psychologist. This study aims to describe role newly implemented CSM French Comprehensive Center. Methods Each week, health-caregivers decide situations be...
Abstract Introduction: In oncology, the care process of chronic patients needs to be personalized. This entails considering both clinical aspects and directly related personal expectations socioeconomic status. However, designing personalized interventions meet each patient’s demands poses an organizational problem. Therefore, PErsonalised Pathway for ONcology (PEPON) -project aims develop evaluate intervention improve personalisation oncology patient pathways. Method protocol follows...
Abstract Background Early phase clinical trials usually include patients with advanced disease who have failed standard therapies. palliative care for these has shown to improve quality of life and even survival. PALLIA 10 score (ranging from 1 10) is a tool developed by the French Palliative Care Society identify best time introduce care. Methods We assessed other prognostic factors (age, ECOG, Royal Marsden Hospital (RMH) score, LDH albumin levels, number prior systemic treatments...
Abstract Background Early palliative care integration into the oncologic treatment pattern is recognized and strongly recommended to anticipate end-of-life issues avoid disproportionate care. Targeted therapies (TTs), with their very rapid onset of action relatively good tolerance, may have an effect on cancer-related symptoms, which could be beneficial in context Methods Data were extracted from a cohort all patients hospitalized acute unit between 03.04.2019 07.04.2020. for consecutive...
Abstract Optimal vaccination and immunotherapy against coronavirus disease COVID-19 relies on the in-depth comprehension of immune responses determining individual susceptibility to be infected by SARS-CoV-2 develop severe disease. We characterized polarity specificity circulating SARS-CoV-2-specific T cell whole virus lysates or 186 unique peptides derived from SARS-CoV-1 ORFeome 296 cancer-bearing 86 cancer-free individuals who were either pre-COVID-19 era (67 individuals) contemporary...
Abstract Purpose : Although sexual health (SH) is a major concern for many patients with breast cancer (BC), only few of them receive adequate information on this topic throughout their whole care pathway. BEROSE single-center pilot cross-sectional observational study, which aimed at evaluating communication SH between women BC and health-care providers. Methods From June 12th to July 31st, 2020, survey was distributed consulting Breast Cancer Unit Gustave Roussy Center. The primary endpoint...