- Circadian rhythm and melatonin
- Enzyme Catalysis and Immobilization
- Microbial Metabolic Engineering and Bioproduction
- Birth, Development, and Health
- Sleep and related disorders
- Sleep and Wakefulness Research
- Biofuel production and bioconversion
- Microbial Metabolites in Food Biotechnology
- Gut microbiota and health
- Spaceflight effects on biology
- Autophagy in Disease and Therapy
- Cell death mechanisms and regulation
- Immune Cell Function and Interaction
- Advanced Sensor and Energy Harvesting Materials
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Tactile and Sensory Interactions
- Advanced Glycation End Products research
- Heat shock proteins research
- Tryptophan and brain disorders
- Neuroendocrine Tumor Research Advances
- Biochemical Acid Research Studies
- RNA and protein synthesis mechanisms
- Cancer-related Molecular Pathways
- Conducting polymers and applications
- Exercise and Physiological Responses
Tianjin University
2023-2024
Beijing Institute of Education
2021-2024
Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences
2021-2024
Ministry of Education of the People's Republic of China
2023
Collaborative Innovation Center of Chemical Science and Engineering Tianjin
2023
Academy of Military Medical Sciences
2020-2021
Hubei University of Chinese Medicine
2020
Chinese People's Liberation Army
2020
Wenzhou-Kean University
2020
Probiotic bacteria have been associated with various health benefits and included in overwhelming number of foods. Today, probiotic supplements are consumed increasing regularity record a rapidly growing economic value. With billions heterogeneous populations probiotics per serving, contain the largest quantity across all functional They often carry antibiotic-resistant determinants that can be transferred to accumulate resident gastrointestinal tract risk their acquisitions by opportunistic...
Long-term, real-time, and comfortable epidermal electronics are of great practical importance for healthcare monitoring human–machine interaction. However, traditional physiological signal confined by the specific clinical sites unreliability electrodes leads to restrictions on its application. Herein, we constructed a solution-processed submicron (down 230 nm), free-standing, breathable sandwich-structured hybrid electrode composed silver nanowire network with conductive polymer film, which...
Abstract Ambient air temperature is a key factor affecting human health. Female reproductive disorders are representative health risk events under low temperature. However, the mechanism involving in cold-induced female remains largely unknown. mice were intermittently exposed to cold conditions (4 °C) address of on system. Primary granulosa cells (GCs) prepared and cultured (35 or β3-adrenoreceptor agonist, isoproterenol, mimic condition exposure. Western-blot, RT-PCR, co-IP, ELISA,...
Disturbed sleep is closely associated with an increased risk of metabolic diseases. However, the underlying mechanisms circadian clock genes linking and lipid profile abnormalities have not been fully elucidated. This study aimed to explore important role in regulating impaired cholesterol metabolism at early stage deprivation (SD). Sleep disturbance was conducted using SD instrument. Our results showed that serum levels. Concentrations leptin resistin were much lower after SD, but other...
Abstract Two catalytic subunits of the IKK complex, IKKα and IKKβ, trigger NF-κB activation as well NF-κB-independent signaling events under both physiological pathological conditions. Here we identified NF-κB-unrelated cytoprotective function in promoting autophagy by triggering p53 transactivation upregulation its downstream autophagic mediator, DRAM1, arsenite-treated hepatoma cells, which responses depended on kinase activity. Furthermore, triggered p53/DRAM1-dependent inducing CHK1...
High altitudes or exposure to hypoxia leads female reproductive disorders. Circadian clocks are intrinsic time-tracking systems that enable organisms adapt the Earth’s 24-h light/dark cycle, which can be entrained by other environmental stimuli regulate physiological and pathological responses. In this study, we focused on whether ovarian circadian clock proteins were involved in regulating dysfunction under hypoxic conditions. Hypobaric was found induce a significantly prolonged estrous...
Abstract Background: Sleep loss leads to a spectrum of mood disorders such as anxiety, cognitive dysfunction and motor coordination impairment in many individuals. However, the underlying mechanisms are largely unknown. Methods: In this study, we examined effects sleep deprivation (SD) on depression mechanism by subjecting rats slowly rotating platform for 3 days mimic process loss. Sleep-deprived animals were tested behaviorally anxiety- depressive-like behaviors. We further studied SD...