A5007011061- Glioma Diagnosis and Treatment
- Aluminum Alloy Microstructure Properties
- Aluminum Alloys Composites Properties
- Metallurgy and Material Forming
- Metal Forming Simulation Techniques
- Metal Alloys Wear and Properties
- Microstructure and Mechanical Properties of Steels
- Brain Metastases and Treatment
- Alcohol Consumption and Health Effects
- Microstructure and mechanical properties
- Mitochondrial Function and Pathology
- Liver Disease Diagnosis and Treatment
- Ruminant Nutrition and Digestive Physiology
- Metabolism and Genetic Disorders
- Copper Interconnects and Reliability
- Metal and Thin Film Mechanics
- Peroxisome Proliferator-Activated Receptors
- ATP Synthase and ATPases Research
- Bone and Joint Diseases
- Single-cell and spatial transcriptomics
- Bone Tissue Engineering Materials
- Bladder and Urothelial Cancer Treatments
- Orthopaedic implants and arthroplasty
- Urinary and Genital Oncology Studies
- CNS Lymphoma Diagnosis and Treatment
Yokohama City University
2023
Keio University
2003-2014
Mansoura University
2013
Showa General Hospital
2011-2012
Shinshu University
2006-2007
Ōtani University
2005
Furukawa Electric (United Kingdom)
2004
University of Tsukuba
1989-2003
Saitama Medical University
2000
Singapore Institute of Manufacturing Technology
2000
The relationship between the low Km aldehyde dehydrogenase (ALDH2) phenotype determined by isoelectric focusing of hair root lysates, facial flushing and alcohol drinking patterns in Japanese (N = 282) was examined. Men who had inactive ALDH2 drank significantly less than those with active ALDH2. Although effect noticeable, a similar detected women. Two types responses were determined: one due to ALDH2, other unrelated this variant form isozyme. A striking difference these types, terms...
Enhancer of zeste homolog 2 (EZH2) enhances tumorigenesis and is commonly overexpressed in several types cancer. To investigate the anticancer effects EZH2 inhibitors, microRNA (miRNA) expression profiles were examined gastric liver cancer cells treated with suberoylanilide hydroxamic acid (SAHA) 3-deazaneplanocin A (DZNep). We confirmed that SAHA DZNep suppressed AGS HepG2 inhibited their proliferation. The results microarray analyses demonstrated miR-1246 was upregulated by treatment...
It has been suggested that a heparin-binding growth factor, midkine (MK), plays an important role in carcinogenesis because of its frequent overexpression various malignant tumours. To clarify whether or not MK contributes to the early stage carcinogenesis, we examined status mRNA 20 adenomas with moderate- and severe-grade dysplasia, 28 carcinomas corresponding normal tissues, by means Northern blotting. The expression level was significantly more elevated than tissues (P < 0.001, unpaired...
Zinc is an essential trace element that has stimulatory effects on bone formation. Recently, we developed zinc-releasing calcium phosphate ceramics in order to add the pharmacologic effect of zinc ceramics. In our previous study, showed optimum content for promoting formation was 0.316 wt %. Therefore a composite ceramic zinc-containing beta-tricalcium and hydroxyapatite, with %, chosen long-term implantation. Cylindrical rods were implanted rabbit femora 2 60 weeks. Using computer-aided...
Formable 980–1470 MPa grade ultra high-strength TRIP-aided sheet steels with bainitic ferrite matrix (TBF steels) have been developed for cold forming of automotive applications. Complex additions 1.0%Al–0.05%Nb–0.2%Mo to 0.2%C–1.5%Si–1.5%Mn base steel increased both the volume fraction and carbon concentration retained austenite films TBF steel, refining microstructure. Extremely much was realized in austempered at 450–500°C, corresponding hot-dip galvanization just after annealing. Good...
Abstract Purpose: The 2021 World Health Organization (WHO) classification of central nervous system (CNS) tumors uses an integrated approach involving histopathology and molecular profiling. Because majority adult malignant brain are gliomas primary CNS lymphomas (PCNSL), rapid differentiation these diseases is required for therapeutic decisions. In addition, diffuse require information on single-nucleotide variants (SNV), such as IDH1/2. Here, we report intraoperative diagnostic (i-ID) to...
[Purpose] Therapeutic exercise for chronic low back pain is one of the most important conservative treatments. Recently, lumbar stabilization focused on deep trunk muscles has attracted considerable attention. This study investigated effectiveness exercises treating CLBP. [Subjects] The subjects were 18 patients with CLBP was defined as that persisted more than 3 months. [Methods] therapeutic involved abdominal drawing-in maneuver (hereafter referred to "drawing-in") and prone kneeling...
Application of Matthiessen's rule to resistivity measurement was examined. An induced empirical relation between and resistance ratio is accurate enough for the A1050 rolled sheets. The change with various heat treatments leads following facts. Some parts Si in alloy precipitate during cold rolling as elemental amount precipitates increases by annealing below 250°C. Dissolution precipitated completes at 400°C. Most Fe have precipitated. further 400°C after rolling. dissolve above up...
To reduce the weight of vehicle body structures, Al–Mg–Si alloys which benefit from artificial aging during paint bake cycle have been used in outer panels automobiles. One important requirements these is their ability to resist fracture hemming. In this paper, effect Si and Fe contents on bendability has investigated. The declined with increasing alloys. It obvious that related size distribution second phase particles. Small cracks surface a specimen seem appear interface between particles...
Regenos® is a unidirectional porous hydroxyapatite (UDPHAp) bone substitutes, and the most distinctive feature of UDPHAp its interconnected structure. We used for defect while distal radius fracture surgery with metal fixation implant. At six months post-operation, CT scans revealed implant was uniformly composed cortical adjacent to trabecular bone. one-year postoperatively, we collected sample implanted plate removal histological evaluation. presence ossified stained green Villanueva...
<p>Single nucleotide detection threshold</p>
<p>Illustrative cases in the retrospective cohort</p>
<div>AbstractPurpose:<p>The 2021 World Health Organization (WHO) classification of central nervous system (CNS) tumors uses an integrated approach involving histopathology and molecular profiling. Because majority adult malignant brain are gliomas primary CNS lymphomas (PCNSL), rapid differentiation these diseases is required for therapeutic decisions. In addition, diffuse require information on single-nucleotide variants (SNV), such as <i>IDH1</i>/2. Here, we report...
<p>Single nucleotide detection threshold</p>