- Mesoporous Materials and Catalysis
- Layered Double Hydroxides Synthesis and Applications
- Zeolite Catalysis and Synthesis
- Catalytic Processes in Materials Science
- Cancer Immunotherapy and Biomarkers
- Congenital Heart Disease Studies
- Bone Metabolism and Diseases
- Endometrial and Cervical Cancer Treatments
- Cholesterol and Lipid Metabolism
- Ovarian function and disorders
- Aerogels and thermal insulation
- Cardiac Health and Mental Health
- Abdominal vascular conditions and treatments
- Sperm and Testicular Function
- Electrolyte and hormonal disorders
- Bone and Dental Protein Studies
- Multicomponent Synthesis of Heterocycles
- Ammonia Synthesis and Nitrogen Reduction
- Acute Kidney Injury Research
- Ionic liquids properties and applications
- MicroRNA in disease regulation
- Cardiac Structural Anomalies and Repair
- Viral Infections and Immunology Research
- Abdominal Surgery and Complications
- Cardiomyopathy and Myosin Studies
Nanjing Medical University
2003-2024
Jiangsu Province Hospital
2009-2024
Harbin Medical University
2024
First Affiliated Hospital of Harbin Medical University
2024
Nanjing University
2002-2013
Sepsis associated Acute kidney injury (AKI) is a common clinical syndrome characterized by suddenly decreased in renal function and urinary volume. This study was designed to investigate the role of Aquaporin 1 (AQP1) P53 development sepsis-induced AKI their potential regulatory mechanisms. Firstly, transcriptome sequencing analysis mice showed AQP1 expression reduced elevated Cecal ligation puncture (CLP)-induced compared with controls. Bioinformatics confirmed that remarkably obviously...
A novel bifunctional mesoporous material MA/SBA-15 has been synthesized in one pot by situ introduction of aluminium and magnesium salts controlling the synthesis conditions, with framework insertion high dispersion magnesia resulting both strong basic acidic sites being simultaneously formed on SBA-15. Characterization low angle X-ray diffraction, N2 adsorption, high-resolution transmission electron microscopes (HRTEM), 1H 27Al magic-angle spinning (MAS) NMR carried out to evaluate effect...
What is known and objective Rituximab a chimeric anti-CD20 IgG1 monoclonal antibody for the treatment of various forms lymphoma haematological autoimmune diseases. Interstitial lung disease rare but lethal pulmonary toxicity rituximab. Nod-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome molecular platform activated upon signs cellular 'danger' to trigger maturation pro-inflammatory cytokines. We report first case rituximab-induced interstitial (R-ILD) with NLRP3...
Genome‐wide association studies (GWASs) have achieved great success in deciphering the genetic cause of congenital heart disease (CHD). However, heritability CHD remains to be clarified, and numerous factors responsible for occurrence are yet unclear. In this study, we performed a genome‐wide search relaxed forms compound heterozygosity (CH) with using our existing GWAS data including 2265 individuals (957 cases 1308 controls). CollapsABEL was used iteratively test between CH genotype...
Objectives This study aimed to investigate the knowledge, attitudes and practical experiences of cardiac surgery nurses regarding kinesiophobia management during early mobilisation. Design Using a descriptive qualitative research method, 21 participated in this from October 2022 January 2023, interview data were analysed using Colaizzi 7-step analysis method. Setting Data collected through in-depth face-to-face or online interviews tertiary hospital located Nanjing, China. Participants...
<h3>Background</h3> We have previously reported that adiponectin (AD), an adipokine is secreted by adipocytes, correlates closely with progressive bone erosion in rheumatoid arthritis (RA). The exact mechanism of AD towards promoting joint destruction remain unclear. <h3>Objectives</h3> Osteopontin (OPN) required for osteoclast recruitment. hypothesised exacerbates inducing OPN expression synovial tissue. This study aimed to evaluate a novel role RA. <h3>Methods</h3> serum levels and were...
Introduction: Aggressive natural killer cell leukemia (ANKL) is an extraordinary rare aggressive malignancy of NK cells, but relatively common in Asian. The accurate diagnosis ANKL remains a great challenge. This study intends to describe the clonality, clinical and genetic features guide this disease. Methods: A total 45 consecutive newly diagnosed patients were recruited from First Affiliated Hospital Nanjing Medical University, data collected. Cytological morphology, flow cytometric...