A5110769358- Cancer Diagnosis and Treatment
- Immunotherapy and Immune Responses
- Colorectal Cancer Screening and Detection
- vaccines and immunoinformatics approaches
- RNA modifications and cancer
- Pleural and Pulmonary Diseases
- Genetic factors in colorectal cancer
- Cancer Risks and Factors
- Lung Cancer Diagnosis and Treatment
- Breast Cancer Treatment Studies
- Lung Cancer Treatments and Mutations
- BRCA gene mutations in cancer
- Lymphoma Diagnosis and Treatment
- Cancer Research and Treatments
- CAR-T cell therapy research
- Ovarian cancer diagnosis and treatment
- DNA Repair Mechanisms
- Cancer Genomics and Diagnostics
- Occupational and environmental lung diseases
- Head and Neck Surgical Oncology
- Education and Critical Thinking Development
- Reflective Practices in Education
- Business, Innovation, and Economy
- Child Abuse and Trauma
- Intraperitoneal and Appendiceal Malignancies
University of Arizona
2012-2025
University of Arizona Cancer Center
2025
Cedars-Sinai Medical Center
2024
Weatherford College
2022
Medical University of South Carolina
2022
Creative Commons
2022
Stony Brook University Hospital
2020-2021
Community College of Allegheny County
2020
Stony Brook University
2018-2020
Universidad Nacional de Asunción
2017-2018
Abstract Purpose: The initial goal of this study was to test the immunologic and clinical effects a new cancer vaccine consisting dendritic cells (DC) transduced with full-length wild-type p53 gene delivered via an adenoviral vector in patients extensive stage small cell lung cancer. Experimental Design: Twenty-nine were vaccinated repeatedly at 2-week intervals. Most received three immunizations. p53-specific responses evaluated, phenotype function T cells, DCs, immature myeloid analyzed...
A logical progression of the widely used microtiter plate ELISA is toward a protein array format that allows simultaneous detection multiple analytes at addresses within single well. Here we describe construction and use such multiplex to measure prostate-specific antigen (PSA), alpha1-antichymotrypsin-bound PSA (PSA-ACT), interleukin-6 (IL-6).We silanized glass plates printed appropriate capture antibodies allow for "sandwich" quantification assays. We examined specificity assay antigen,...
We report a single center phase II trial of sequential vaccination followed with vaccine plus interleukin-2 (IL-2). Vaccination consisted autologous cells cultured from primary tumor or resected metastasis, transduced to express B7.1 surface molecule and then irradiated. The would hypothetically costimulate tumor-reactive T before IL-2 exposure. Treatment plan was 3 subcutaneous injections at 4-week intervals treatment for 6 weeks starting week 7. Sixty-six patients enrolled, whom 39...
Abstract Background Addressing critical gaps in precision medicine initiatives colorectal cancer (CRC) requires building larger collaborative studies. Methods The Latino Colorectal Cancer Consortium (LC3) is a resource that harmonizes data collected observational studies with from individuals who identify as Hispanic/Latino diagnosis of primary adenocarcinoma. Data includes demographics, medical history, family and lifestyle risk factors patient-completed surveys. Vital status, cause death,...
Genomic analysis of a patient's tumor is the cornerstone precision oncology, but it does not address whether metastases should be treated differently. Here we tested comparative single-cell RNA sequencing (scRNA-seq) primary small intestinal neuroendocrine to matched liver metastasis could guide treatment metastatic disease. Following surgery, patient was put on maintenance with somatostatin analog. However, scRNA-seq revealed that epithelial cells in were less differentiated and expressed...
Biliary complications account for significant morbidity in orthotopic liver transplantation (OLT), with a reported incidence ranging from 6% to 47%, and many centers are reassessing the need options available stenting biliary anastomosis. We report on our experience using 6F Silastic, double-J, ureteral stent as an internal OLT. From October 15, 1995, September 30, 1998, total of 99 patients at institution underwent 108 OLTs. Of these, 77 received end-to-end choledochocholedochostomy over...
The epithelial to mesenchymal transition (EMT) plays a key role in lung cancer progression and drug resistance. dynamics stability of gene expression patterns as cells from E M at systems level relevance patient outcomes are unknown. Using comparative network clustering analysis, we systematically analyzed time-series data cell lines H358 A549 that were induced undergo EMT. We also predicted the putative regulatory networks controlling EMT dynamics, especially for EMT-dynamic genes related...
ANDERSON, JULIE RN, CCRC, PHD; LANGEMO, DIANE PHD, FAAN; HANSON, DARLENE MS; THOMPSON, PATRICIA HUNTER, SUSAN MSN Author Information
Abstract Introduction. Financial toxicity affects 30-70% of cancer patients. There is limited data on interventions to address practical and financial information needs that could mitigate for community individuals affected by cancer. Our objective was test feasibility a pilot educational webinar intervention assess patient reported outcomes, knowledge, satisfaction. Methods. An advertised Los Angeles Public Library delivered organization Triage Cancer. Four live webinars focused...
The United States has seen a decrease in the incidence of bladder cancer and decline mortality rates over past 20 years. However, not all groups have benefited equally from this trend. American Association Community Cancer Centers (ACCC) issued ten strategies to improve care delivery for underserved patient populations. Unfortunately, evidence supporting best methods reducing disparities different settings remains severely limited. In short communication, using personalized narrative woven...
Abstract In the colonial periods of settlement in both Australia and Aotearoa New Zealand provision education for children was primarily responsibility state. As state systems developed, Catholic authorities recognised need schools which provided secular religious children. mid-nineteenth century, Australian-born Mary MacKillop Fr Julian Tenison Woods founded Sisters Saint Joseph Sacred Heart purpose providing rural areas vast land Australia. This article traces story struggles establishment...
Ser profesional es el anhelo de todo estudiante pero son pocos los que concluyen sus estudios y eso se da por diferentes factores. La presente investigación desarrolló con objetivo determinar la cantidad estudiantes Facultad Ciencias Económicas Universidad Nacional Asunción culminaron Carrera Administración - Plan Curricular 2001, en turno mañana durante periodo 2011 2016, para lo cual metodología utilizada fue mixta porque vincularon informaciones cualitativas cuantitativas, aplicándose...
Polycythemia (venous hematocrit >65%) is rare in healthy newborns (incidence: 0.4%-5%), with serious outcomes (stroke, bowel ischemia) of unknown incidence asymptomatic infants. No national guidelines address screening or management infants polycythemia. Our nursery screened "high risk" (HR) (small for gestational age, large twin, infant diabetic mother) poor adherence and low yield. We aimed to decrease polycythemia HR by 80% within 6 months.We conducted an improvement project at a tertiary...
Hunter, Susan MSN, RN; Langemo, Diane PhD, RN, FAAN; Thompson, Patricia MS, Hanson, Darlene Anderson, Julie CCRC Author Information