俊一 久保

ORCID: 0009-0007-4375-0652
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About
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Research Areas
  • Orthopaedic implants and arthroplasty
  • Colorectal Cancer Treatments and Studies
  • Spinal Fractures and Fixation Techniques
  • Hip disorders and treatments
  • Total Knee Arthroplasty Outcomes
  • Spine and Intervertebral Disc Pathology
  • Shoulder Injury and Treatment
  • Bone health and treatments
  • Musculoskeletal synovial abnormalities and treatments
  • Cancer, Lipids, and Metabolism
  • Orthopedic Infections and Treatments
  • Shoulder and Clavicle Injuries
  • Orthopedic Surgery and Rehabilitation
  • Medical Imaging and Analysis
  • Bone and Joint Diseases
  • Peripheral Nerve Disorders
  • Musculoskeletal Disorders and Rehabilitation
  • Metabolomics and Mass Spectrometry Studies
  • Medical Research and Treatments
  • Nerve Injury and Rehabilitation
  • Colorectal Cancer Screening and Detection
  • Vascular Malformations Diagnosis and Treatment
  • Oral and Maxillofacial Pathology
  • Osteomyelitis and Bone Disorders Research
  • Scoliosis diagnosis and treatment

Nanjing University of Chinese Medicine
2025

Nanjing Drum Tower Hospital
2025

Jiangsu Cancer Hospital
2024

To identify genes differentially expressed between resistant and sensitive BRAF V600E melanoma cell lines using bioinformatics tools applied to GEO data. We retrieved downloaded the target gene set (GSE45558) from database used R software filter (DEGs) resistant. The identified DEGs were subjected GO functional enrichment analysis (including biological processes, molecular functions, cellular components) Kyoto Encyclopedia of Genes Genomes (KEGG) pathway analysis, utilizing software....

10.1007/s00403-025-03895-8 article EN cc-by-nc-nd Archives of Dermatological Research 2025-03-01

Abstract Colorectal cancer is frequently diagnosed in advanced stages, highlighting the need for developing approaches early detection. Liquid biopsy using cell-free DNA (cfDNA) fragmentomics a promising approach, but clinical application hindered by complexity and cost. This study aimed to develop an integrated model cfDNA accurate, cost-effective early-stage colorectal Plasma was extracted sequenced from training cohort of 360 participants, including 176 patients with 184 healthy controls....

10.1158/0008-5472.can-23-3486 article EN Cancer Research 2024-07-29

<div>Abstract<p>Colorectal cancer is frequently diagnosed in advanced stages, highlighting the need for developing approaches early detection. Liquid biopsy using cell-free DNA (cfDNA) fragmentomics a promising approach, but clinical application hindered by complexity and cost. This study aimed to develop an integrated model cfDNA accurate, cost-effective early-stage colorectal Plasma was extracted sequenced from training cohort of 360 participants, including 176 patients with...

10.1158/0008-5472.c.7474569 preprint EN 2024-10-01
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