Dongzheng Li

ORCID: 0009-0007-8098-3391
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About
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Research Areas
  • Colorectal Cancer Treatments and Studies
  • Cancer, Lipids, and Metabolism
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Metabolomics and Mass Spectrometry Studies
  • Ferroptosis and cancer prognosis
  • Luminescence Properties of Advanced Materials
  • Colorectal Cancer Screening and Detection
  • Metastasis and carcinoma case studies
  • Cancer Genomics and Diagnostics
  • Inflammatory Biomarkers in Disease Prognosis
  • Bladder and Urothelial Cancer Treatments
  • Spine and Intervertebral Disc Pathology
  • interferon and immune responses
  • Pelvic and Acetabular Injuries
  • bioluminescence and chemiluminescence research
  • Immune Cell Function and Interaction
  • Ubiquitin and proteasome pathways
  • Spinal Fractures and Fixation Techniques
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Cancer-related molecular mechanisms research
  • Radiation Detection and Scintillator Technologies
  • Genetic factors in colorectal cancer

Nanjing Medical University
2022-2025

Jiangsu Province Hospital
2024-2025

Xuzhou Medical College
2024

Affiliated Hospital of Xuzhou Medical College
2024

Jiangsu Cancer Hospital
2024

Chinese Academy of Medical Sciences & Peking Union Medical College
2022

Objective: To evaluate the survival benefit of surgical treatment for intrahepatic cholangiocarcinoma. Methods: This study was conducted based on hepatobiliary tumor registry database. From May 2009 to December 2022,a total 704 patients who were initially diagnosed with cholangiocarcinoma and underwent liver resection consecutively enrolled at Hepatobiliary Center First Affiliated Hospital Nanjing Medical University. Among them,there 380 males 324 females,aged (M(IQR)) 61(15) years(range:27...

10.3760/cma.j.cn112139-20240927-00443 article EN PubMed 2025-03-07

Abstract Colorectal cancer is frequently diagnosed in advanced stages, highlighting the need for developing approaches early detection. Liquid biopsy using cell-free DNA (cfDNA) fragmentomics a promising approach, but clinical application hindered by complexity and cost. This study aimed to develop an integrated model cfDNA accurate, cost-effective early-stage colorectal Plasma was extracted sequenced from training cohort of 360 participants, including 176 patients with 184 healthy controls....

10.1158/0008-5472.can-23-3486 article EN Cancer Research 2024-07-29

The intricate interplay between the platelet-coagulation system and progression of malignant tumors has profound therapeutic implications. However, a thorough examination platelet coagulation markers specific to colorectal cancer (CRC) is conspicuously absent in current literature. Consequently, there an urgent need for further exploration into mechanistic underpinnings these their potential clinical applications.

10.3390/biomedicines12102225 article EN cc-by Biomedicines 2024-09-30

<div>Abstract<p>Colorectal cancer is frequently diagnosed in advanced stages, highlighting the need for developing approaches early detection. Liquid biopsy using cell-free DNA (cfDNA) fragmentomics a promising approach, but clinical application hindered by complexity and cost. This study aimed to develop an integrated model cfDNA accurate, cost-effective early-stage colorectal Plasma was extracted sequenced from training cohort of 360 participants, including 176 patients with...

10.1158/0008-5472.c.7474569 preprint EN 2024-10-01

<title>Abstract</title> <bold>Background: </bold>Percutaneous vertebroplasty (PVP) and percutaneous kyphoplasty (PKP) are two minimally invasive surgical procedures have achieved satisfactory outcomes in the treatment of mild to moderate osteoporotic vertebral compression fractures (OVCF) .However, severe (sOVCF),used been regarded as relative or even absolute contraindication for PVP PKP.To date, there is still no consensus on optimal strategy sOVCF. <bold>Methods: </bold>A retrospective...

10.21203/rs.3.rs-5340494/v1 preprint EN cc-by Research Square (Research Square) 2024-12-03

Objective: To study the surgical safety and efficacy of preoperative neoadjuvant therapy with immune checkpoint inhibitors combined anti-angiogenic drugs in patients China liver cancer staging(CNLC)-Ⅱb Ⅲa resectable hepatocellular carcinoma. Methods: The data 129 Ⅱb carcinoma who underwent surgery at First Affiliated Hospital Nanjing Medical University from January 2018 to December 2020 were analyzed. All divided into two groups: group(n=14,13 males 1 female,aged (55.4±12.6)years(range:34 75...

10.3760/cma.j.cn112139-20220408-00150 article EN PubMed 2022-07-01
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