YouRu Wu

ORCID: 0009-0007-5277-2079
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Research Areas
  • Crystallization and Solubility Studies
  • X-ray Diffraction in Crystallography
  • Metal complexes synthesis and properties
  • RNA modifications and cancer
  • Synthesis and Characterization of Heterocyclic Compounds
  • Metal-Organic Frameworks: Synthesis and Applications
  • Image Processing and 3D Reconstruction
  • Ferroptosis and cancer prognosis
  • Synthesis and biological activity
  • Autophagy in Disease and Therapy
  • Cryospheric studies and observations
  • Wnt/β-catenin signaling in development and cancer
  • Neonatal Respiratory Health Research
  • Cancer Research and Treatments
  • Hops Chemistry and Applications
  • Remote Sensing and Land Use
  • Neuroscience of respiration and sleep
  • Winter Sports Injuries and Performance
  • Virtual Reality Applications and Impacts
  • Cerebrospinal fluid and hydrocephalus
  • Epigenetics and DNA Methylation
  • Crystallography and molecular interactions
  • Fermentation and Sensory Analysis
  • Ecology and Conservation Studies
  • Remote Sensing and LiDAR Applications

Guilin Medical University
2020-2024

Beihang University
2022-2024

Affiliated Eye Hospital of Wenzhou Medical College
2024

Wenzhou Medical University
2024

Center Point
2022

Oceaneering International (United States)
2022

Bridge University
2022

Guangxi University
2017

Abstract The glymphatic-lymphatic system is increasingly recognized as fundamental for the homeostasis of brain milieu since it defines cerebral spinal fluid flow in parenchyma and eliminates metabolic waste. Animal human studies have uncovered several important physiological factors regulating glymphatic including sleep, aquaporin-4, hemodynamic factors. Yet, our understanding modulation limited, which has hindered development glymphatic-based treatment aging neurodegenerative disorders....

10.1038/s41421-024-00701-z article EN cc-by Cell Discovery 2024-08-06

Induction of cuproptosis and targeting multiple signaling pathways show promising applications in tumor therapy. In this study, we synthesized two thiosemicarbazone-copper complexes ([Cu

10.1021/acs.jmedchem.4c00257 article EN Journal of Medicinal Chemistry 2024-05-23

Abstract DEP domain containing 1(DEPDC1) is involved in the tumorigenesis of a variety cancers. But its role lung adenocarcinoma (LUAD) not fully understood. Here, we investigated and underlying mechanisms DEPDC1 development LUAD. The expression prognostic values LUAD were analysed by using data from public databases. Gene enrichment TCGA was GSEA software with pre‐defined gene sets. Cell proliferation, migration invasion A549 cells examined colony formation, Transwell wound healing assays....

10.1111/jcmm.15947 article EN cc-by Journal of Cellular and Molecular Medicine 2020-10-05

The Pluronic F127 thermosensitive hydrogels containing copper complex 3 were constructed, which could delay A549 tumor xenograft growth effectively with lower systemic toxicity.

10.1039/d2qi01383e article EN Inorganic Chemistry Frontiers 2022-01-01

Background Lung adenocarcinoma (LUAD) is a major type of lung cancer with poor prognosis and low 5-year survival rate, which urgently needs further investigation in order to elucidate its mechanisms completely discover novel therapeutic targets. C1orf74 protein unknown function either normal cells or cells. The aim this study investigate the expression LUAD Methods was analyzed using datasets from public databases. prognostic value Kaplan-Meier Plotter. cell line A549, H1993 HCC827 silenced...

10.7717/peerj.13908 article EN cc-by PeerJ 2022-08-22

3D terrain reconstruction technology can produce mathematical models corresponding to real scenes, and be applied research fields such as scientific exploration, heritage conservation architectural design. Taking the Mount Everest an example, this paper realizes construction of a model in UE4 (Unreal Engine 4) by high-precision DEM (Digital Elevation Model), explore cause step-like surface solve it. Using for improve efficiency using help into subsequent applications.

10.1117/12.3029732 article EN 2024-06-21

The aim of this work was to develop a novel method using chiral column determine the terpene alcohol isomers in hops and beer. An optimum procedure designed, storage variation within one month tested. results sum by new unseparated with nonchiral were compared. statistical comparison demonstrated validity employing column. This applied analysis 18 varieties 14 brands showed that R-(–)-linalool primary linalool enantiomer but not beers. R-(+)-β-citronellol, S-(–)-β-citronellol, citronellyl...

10.1094/asbcj-2017-2293-01 article EN Journal of the American Society of Brewing Chemists 2017-04-01

The difficulty of climbing Mount Everest has been gradually reduced with the continuous progress technology, but there are still great risks. In response to current problem high threshold for Everest, this paper proposes a virtual interactive mountaineering map based on DEM (Digital Elevation Model) data. restores real terrain features and landform characteristics region, simulates climate environment under different weather conditions according data region. can provide enthusiasts...

10.1109/iccece54139.2022.9712742 article EN 2022 2nd International Conference on Consumer Electronics and Computer Engineering (ICCECE) 2022-01-14

The NICE‑3 protein serves an oncogenic role in hepatocellular carcinoma, but its lung adenocarcinoma (LUAD) remains unknown. aim of the present study was to investigate potential and underlying mechanisms LUAD. In study, expression LUAD tissues association with patient prognosis were analyzed using datasets from Cancer Genome Atlas Gene Express Omnibus. After NICE‑3‑knockdown small interfering RNA cells, cell proliferation measured by counting, cycle examined flow cytometry, invasion...

10.3892/etm.2021.10057 article EN Experimental and Therapeutic Medicine 2021-04-15

Abstract Background Sperm-associated antigen 1 (SAPG1) expression is increased in multiple cancer tissues, but the role and mechanisms of SPAG1 lung remain unknown. The present study was aimed to investigate SPAG1’s function adenocarcinoma (LUAD). Methods LUAD tissues evaluated by analyzing three datasets, its association with prognosis patients accessed using Kaplan-Meier Plotter. were investigated cells vitro. effect on tumor growth xenografts. In addition, molecular domain involved...

10.21203/rs.3.rs-617727/v1 preprint EN cc-by Research Square (Research Square) 2021-06-22

三维地形重建技术可以生成对应于真实场景的数学模型,应用于科学探索、遗产保护和建筑设计等研究领域。本文以珠穆朗玛峰为例,通过高精度DEM(Digital Elevation Model)在UE4(Unreal Engine 4)中实现了真实地形模型的构建,并探讨了模型表面出现阶梯状和解决这个问题。使用UE4进行重建可以提高地形模型的使用效率,有助于地形模型进入后续应用。

10.2139/ssrn.4326446 article ZH-CN 2023-01-01

Haptic interface is a platform that convey haptic stimuli to represent and transmit information through touch. This paper systematically focus the achievements of multisensory interaction in virtual reality environment on perspectives human-computer research: immersive experience emotional expression, proposes an evaluation system based Quality Experience (QoE) model aimed quantitatively analyze enhance user interfaces with its statistical significance, which assists researchers engineers...

10.54941/ahfe1002077 article EN AHFE international 2022-01-01
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