A5080514181- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Lung Cancer Diagnosis and Treatment
- RNA modifications and cancer
- Head and Neck Cancer Studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Radiomics and Machine Learning in Medical Imaging
- Cancer survivorship and care
- Glutathione Transferases and Polymorphisms
- Cancer Immunotherapy and Biomarkers
- Colorectal Cancer Treatments and Studies
- Nutrition, Genetics, and Disease
- Neuroendocrine Tumor Research Advances
- Global Cancer Incidence and Screening
- Nutrition and Health in Aging
- Multiple and Secondary Primary Cancers
- Cancer Genomics and Diagnostics
- HER2/EGFR in Cancer Research
- Cancer Diagnosis and Treatment
- Smoking Behavior and Cessation
- Genomics, phytochemicals, and oxidative stress
- Chemotherapy-induced cardiotoxicity and mitigation
- Biomedical Text Mining and Ontologies
- Childhood Cancer Survivors' Quality of Life
- Cholangiocarcinoma and Gallbladder Cancer Studies
Mayo Clinic in Florida
2014-2025
Mayo Clinic in Arizona
2006-2024
Mayo Clinic
2011-2023
WinnMed
2009-2023
Department of Medical Sciences
2014-2017
Nanjing Medical University
2011
Nanjing University
2011
Nanjing General Hospital of Nanjing Military Command
2011
Army Medical University
2011
University of Rochester
2010
Abstract BACKGROUND. Primary salivary‐type lung cancers are rare tumors that include adenoid cystic carcinoma (ACC) and mucoepidermoid (MEC). The clinicopathologic profiles, symptoms on presentation, long‐term outcomes of patients with ACC MEC as an overall group have not been defined recently. METHODS. In this study, the authors analyzed clinical outcome data from 62 who presented a diagnosis primary cancer at Mayo Clinic (Rochester, Minn) 1972 to 2002. RESULTS. median age for was 40 years...
Purpose Evidence has suggested a clinically meaningful relationship between self-reported quality of life (QOL) patient with cancer at the time receiving diagnosis and overall survival (OS). This study evaluated prognostic value QOL assessments regard to OS in large cohort patients lung cancer. Patients Methods A total 2,442 non–small-cell were observed 1997 2007 completed single-item measure within first 6 months diagnosis; these dichotomized using an priori definition deficient score (CDS;...
Genetic susceptibility in lung cancer risk has long been recognized but remains ill defined, as does the role of tobacco smoke exposure and chronic obstructive pulmonary disease (COPD).Using a dual case-control design, we tested whether alpha(1)-antitrypsin deficiency (alpha(1)ATD) carriers are predisposed to higher cancer, adjusting for effects COPD. A total 1856 patients with incident were included study; 1585 community residents served controls. second control group was composed 902 full...
We evaluated somatic genetic alterations in the kinase domain of EGFR gene tumors 219 non-small cell lung cancer patients primarily Caucasian and African American origins. identified 26 (12%) whose had a mutation gene, 11 (5%) carried novel genomic variations consistent with germ-line polymorphisms. All but one were affected adenocarcinoma. mutations more frequent women nonsmokers, significant portion men (12 26) current or past smokers accounted for half (13 26). Screening subjects may...
Novel and targetable mutations are needed for improved understanding treatment of lung cancer in never-smokers. Twenty-seven adenocarcinomas from never-smokers were sequenced by both exome mRNA-seq with respective normal tissues. Somatic detected compared pathway deregulation, tumor phenotypes clinical outcomes. Although somatic DNA or mRNA ranged hundreds to thousands each tumor, the overlap between two only a few couple hundreds. The number either was not significantly associated...
Lung cancer screening using low-dose computed tomography is recommended for high-risk individuals by professional associations including the US Preventive Services Task Force (USPSTF).1 The implications of USPSTF criteria were investigated in a retrospective study well-defined population to demonstrate trends proportion lung patients meeting over 28 years.
There is some initial evidence that an enhanced physical activity level can improve fquality of life, and possibly survival among patients with lung cancer. The primary aim this project was to evaluate the impact on quality quantity life cancer survivors. Between January 1, 1997, December 31, 2009, a total 1466 survivors completed questionnaire patient-reported outcomes for (QOL), demographics, disease clinical characteristics, measure (Baecke Questionnaire). Chi-square tests compared who...
Dermatologic toxicities associated with targeted therapies may impact drug intolerance and predict response, among which rash is most frequently reported well delineated. However, the profile effect of non-rash dermatologic toxicity are not fully understood. We identified stage-IV non-small cell lung cancer patients diagnosed at Mayo Clinic in 2006-2019 systematically analyzed demographics, agents, toxicity, survival outcomes who received therapy. Five subgroups-none, only dermatologic,...