A5101077394- Air Quality and Health Impacts
- Atmospheric chemistry and aerosols
- Air Quality Monitoring and Forecasting
- Atmospheric aerosols and clouds
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Breast Cancer Treatment Studies
- Cardiac pacing and defibrillation studies
- Atrial Fibrillation Management and Outcomes
- Cancer-related Molecular Pathways
- Cervical Cancer and HPV Research
- Cardiac Imaging and Diagnostics
- RNA modifications and cancer
- Angiogenesis and VEGF in Cancer
- Breast Lesions and Carcinomas
- Atmospheric Ozone and Climate
- Vehicle emissions and performance
- Lymphatic System and Diseases
- Molecular Biology Techniques and Applications
- Climate Change and Health Impacts
- Mesenchymal stem cell research
- Medical Imaging Techniques and Applications
- Wind and Air Flow Studies
- Cancer, Hypoxia, and Metabolism
- Chemotherapy-induced cardiotoxicity and mitigation
Tianjin Meteorological Bureau
2013-2024
Army Medical University
2012-2024
Yangzhou University
2023-2024
The Affiliated Yongchuan Hospital of Chongqing Medical University
2024
Chongqing Medical University
2024
Dalian Medical University
2024
Air Force Medical University
2005-2023
Xijing Hospital
2004-2023
Changzhou No.2 People's Hospital
2023
Nanjing Medical University
2023
Background — Implantable cardioverter defibrillator (ICD) use reduces mortality in patients with serious ventricular arrhythmias compared antiarrhythmic drug (AAD) use. However, the relative impact of these therapies on self-perceived quality life (QoL) is unknown. Methods and Results Three self-administered instruments were used to measure generic disease-specific QoL Antiarrhythmics Versus Defibrillators trial participants. Generalized linear models assess relationships between treatment...
As an emerging treatment strategy for triple-negative breast cancer (TNBC), immunotherapy acts in part by inducing ferroptosis. Recent studies have shown that protein arginine methyltransferase 5 (PRMT5) has distinct roles among multiple cancers modulating the tumor microenvironment. However, role of PRMT5 during ferroptosis, especially TNBC immunotherapy, is unclear.PRMT5 expression was measured IHC (immunohistochemistry) staining. To explore function ferroptosis inducers and functional...
Obstructive apneas and hypopneas during sleep are a well recognized cause of excessive daytime sleepiness. Snoring is also associated with excess sleepiness, although it not known whether this reflects an independent effect snoring or simply marker for obstructive apnea. To further explore the relation to we conducted cross-sectional cohort study community-dwelling adults participating in Sleep Heart Health Study. The sample comprises 2,737 men 3,040 women mean age 64 (SD 11) yr. Sleepiness...
Meteorological and aerosol data were measured at the atmospheric boundary layer observation station in Tianjin, China, analyzed to study effects of mass, composition, size distributions on visibility short-wave radiation flux. The results show that fine particles played important roles controlling Tianjin. major contributors light extinction coefficients included sulfate (28.7%), particulate organic matter (27.6%), elemental carbon (19.2%), nitrate (6.1%). In addition measurement...
Ubiquitin-specific protease 22 (USP22), a novel deubiquitinating enzyme, has been associated with metastasis, therapy resistance, and cell cycle progression. The purpose of this study was to investigate the expression level USP22 in papillary thyroid carcinoma (PTC) samples evaluate its clinical significance PTC patients. examined 30 fresh tissues paired adjacent noncancerous by real-time quantitative RT-PCR. Immunohistochemistry for performed on additional 156 tissues. analyzed. We found...
Non-small cell lung cancer (NSCLC) is a highly lethal disease worldwide.We found the pseudogene-derived lncRNA PTTG3P upregulated in NSCLC and associated with larger tumor size, advanced staging, poor prognosis.This study investigated oncogenic roles mechanisms of NSCLC.We demonstrate that promoted proliferation, migration, tumorigenesis, metastasis while inhibiting apoptosis vitro vivo.Mechanistically, formed an RNA-protein complex ILF3 to maintain MAP2K6 E2F1 mRNA stability, two factors...
The purpose of this study was to detect the expression autophagy-related gene Beclin1 and apoptosis-related genes Bcl-2 Bax in breast cancer tissues, investigate their relationship significance occurrence development cancer, provide an experimental basis for biological treatment future. Human tissues relatively healthy tissue adjacent tumor were collected during surgical resection. By using RT-PCR western blot, mRNA protein expressions Beclin1, Bcl-2, detected healthy, tissues. correlations...
Lymph node status is one of the decisive prognostic factors in breast cancer. Chemotherapy targeting regional lymphatic tissues has emerged as a promising therapy for treatment malignancies with high tendency to disseminate lymphatically. The present study determined drug concentrations axillary lymph nodes after chemotherapy (LC) patients cancer and compared results those receiving intravenous (VC) investigate whether LC could improve accumulation anticancer nodes. Sixty carcinoma confirmed...
Human papillomavirus (HPV) is the principal cause of invasive cervical cancer and benign genital lesions. There are currently 30 HPV types linked to cancer. infection also leads other We developed a 61-plex analysis these by examining two genes, E6 L1, using MassARRAY matrix-assisted laser desorption ionization-time flight mass spectrometry (MALDI-TOF MS) (PCR-MS). Two hundred samples from homosexual males (HM) were screened PCR-MS MY09/MY11 primer set-mediated PCR (MY-PCR) followed...
Recombinant human endostatin (rh-endostatin) is a novel antiangiogenesis drug developed in China. Previous experiments have shown that rh-endostatin can inhibit the proliferation and migration of endothelial cells some types tumor cells. In this study, we evaluated efficacy safety profiles combination therapy neoadjuvant chemotherapy for breast cancer patients prospective, randomized, controlled, phase II trial. Sixty-eight with core-biopsy confirmed were allocated randomly to two groups...
To further assess the efficacy and safety of recombinant human endostatin (rh‐endostatin), a Phase III, multicenter, prospective, randomized, controlled clinical trial was conducted. Patients to be treated with neoadjuvant docetaxel epirubicin (DE) or DE plus rh‐endostatin (DEE) were eligible for this trial. The primary endpoint clinical/pathological response. Secondary endpoints included adverse events quality life (QOL). Finally, 803 patients enrolled randomly assigned receive ( n = 402)...