A5108059194- Gut microbiota and health
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Protein Structure and Dynamics
- Pluripotent Stem Cells Research
- Diet and metabolism studies
- CRISPR and Genetic Engineering
- Ammonia Synthesis and Nitrogen Reduction
- Advanced Photocatalysis Techniques
- Epigenetics and DNA Methylation
- Plant biochemistry and biosynthesis
- Analytical Chemistry and Chromatography
- MXene and MAX Phase Materials
- Plant and animal studies
- Advanced Nanomaterials in Catalysis
- Neurobiology and Insect Physiology Research
- Supramolecular Self-Assembly in Materials
- Food composition and properties
- Genetic Mapping and Diversity in Plants and Animals
- RNA Research and Splicing
- Enzyme Structure and Function
- Metal-Organic Frameworks: Synthesis and Applications
- Receptor Mechanisms and Signaling
- Acoustic Wave Resonator Technologies
- Cancer-related molecular mechanisms research
Soochow University
2024-2025
First Affiliated Hospital of Soochow University
2024-2025
Zhengzhou University
2025
Zhongyuan University of Technology
2025
Ningxia Medical University
2023-2025
Shanghai First Maternity and Infant Hospital
2020-2025
Ningxia Medical University General Hospital
2025
Smart Material (Germany)
2025
Chinese Academy of Sciences
2000-2024
China Agricultural University
2022-2024
Nitrate reduction to ammonia (NRA) is critical and attractive for environmental remediation energy conservation. Copper represents one of the most promising non-noble-metal NRA electrocatalysts while its intrinsic catalytic activity facets pH influence remain unclear. Using density functional theory calculations, nitrate pathways are evaluated on low-index crystal surfaces, Cu(111), Cu(100), Cu(110), at different pH. Systematic thermodynamic kinetic analysis indicates that pathway NO3– →...
Multifunctional nanoplatforms for imaging-guided synergistic antitumor treatment are highly desirable in biomedical applications. However, anticancer is largely affected by the pre-existing hypoxic tumor microenvironment (TME), which not only causes resistance of tumors to photodynamic therapy (PDT), but also promotes tumorigenesis and progression. Here, a continuous O
During the traumatic brain injury (TBI), improved expression of circulatory miR-21 serves as a diagnostic feature. Low levels exosome-miR-21 in can effectively improve neuroinflammation and blood-brain barrier (BBB) permeability, reduce nerve apoptosis, restore neural function ameliorate TBI. We evaluated role macrophage derived exosomes-miR-21 (M-Exos-miR-21) disrupting BBB, deteriorating TBI, Rg1 interventions. IL-1β-induced macrophages (IIM)-Exos-miR-21 activate NF-κB signaling pathway...
Surface functionalization is found to overcome the hydrogenation limit for M 3 C 2 MXenes, efficiently promoting nitrate reduction ammonia.
The active component of copper-based materials for electrocatalytic nitrate reduction to ammonia (NRA) remains unclear due the susceptibility oxidation copper. Using density functional theory calculations, NRA pathways are evaluated on low-index crystal surfaces Cu2O (111), CuO and Cu (111) at different pH. with abundant undercoordinated atoms surface, shows easier adsorption NO3– than or (111). is hindered by large ΔG hydrogenation *NO. Thus, contribute most activity while inert. Three key...
Microbial communities such as those residing in the human gut are highly diverse and complex, many with important implications for health diseases. The effects functions of these microbial determined not only by their species compositions diversities but also dynamic intra- inter-cellular states at transcriptional level. Powerful scalable technologies capable acquiring single-microbe-resolution RNA sequencing information order to achieve a comprehensive understanding complex together hosts...
Previous studies have demonstrated that L. delbrueckii plays beneficial roles in modulating the gut microbiota, enhancing intestinal barrier, and promoting animal growth. Postbiotics a similar or even superior effect protecting health compared to probiotics due their excellent stability, extended shelf life, safety. However, protective effects underlying mechanism of postbiotics from inflammation remain unclear. In this study, we impact on by establishing S. Typhimurium-induced model mice,...
Abstract High‐rate lithium/sodium ion batteries or capacitors are the most promising functional units to achieve fast energy storage that highly depends on charge host materials. Host materials with lamellar structures a good choice for hybrid hosts (capacitor redox type). Emerging layered transition metal carbo‐chalcogenides (TMCC) homogeneous sulfur termination especially attractive storage. Using density theory calculations, six of 30 potential TMCC screened be stable, metallic,...
Conformational dynamics is important for protein functions, many of which are performed in cells. How the intracellular environment may affect conformational largely unknown. Here, loop studied a model Escherichia coli cells by using nuclear magnetic resonance (NMR) spectroscopy. The weak interactions between and surrounding macromolecules hinder rotational diffusion, extends dynamic detection timescale up to microseconds NMR spin relaxation method. picosecond microsecond confirmed...
Abstract Introducing multiple physical cues to control cell behaviors effectively is considered as a promising strategy in developing bioactive wound dressings. Silk nanofiber‐based cryogels are developed favor angiogenesis and tissue regeneration through tuning hydrated state, microporous structure, mechanical property, but remained challenge endow with more cues. Here, β ‐sheet rich silk nanofibers used develop nanopore structure. Through optimizing crosslinking time exposing the reactive...