A5038772433- Neutrino Physics Research
- Particle physics theoretical and experimental studies
- Astrophysics and Cosmic Phenomena
- Single-cell and spatial transcriptomics
- Extracellular vesicles in disease
- Dark Matter and Cosmic Phenomena
- Biochemical effects in animals
- Ammonia Synthesis and Nitrogen Reduction
- ATP Synthase and ATPases Research
- Cancer-related molecular mechanisms research
- Radiation Detection and Scintillator Technologies
- Sleep and Wakefulness Research
- Atomic and Subatomic Physics Research
- Circadian rhythm and melatonin
- Nuclear Physics and Applications
- Catalytic Processes in Materials Science
- Hydrogen Storage and Materials
- Particle Detector Development and Performance
- Mitochondrial Function and Pathology
- Neuroscience and Neuropharmacology Research
Soochow University
2025
Wuhan University
2023-2024
Kyoto University
2023-2024
Zhongnan Hospital of Wuhan University
2023-2024
RIKEN Center for Biosystems Dynamics Research
2024
Westlake University
2024
Shanghai Jiao Tong University
2022-2023
Frontier Science Foundation
2023
Abstract The Jiangmen Underground Neutrino Observatory (JUNO) is a multi-purpose experiment, under construction in southeast China, that designed to determine the neutrino mass ordering and precisely measure oscillation parameters. Monte Carlo simulation plays an important role for JUNO detector design, commissioning, offline data processing, physics processing. experiment has world’s largest liquid scintillator instrumented with many thousands of PMTs. broad energy range interest, long...
Abstract Acute sleep deprivation (ASD) negatively impacts fear memory, but the underlying mechanisms are not fully understood. Transient receptor potential vanilloid 4 (TRPV4), a cation channel which is closely correlated with concentration of Ca 2+ , and neuronal overloading crucial inducement learning memory impairment. This study utilized an acute sleep-deprived mouse model combined conditioning to investigate these mechanisms. mRNA sequencing revealed increased expression TRPV4 in mice...
Revealing the heterogeneity among tissues is greatest advantage of single-cell-sequencing. Marker genes not only act as key to correctly identify cell types, but also bio-markers for cell-status under certain experimental imputations. Current analysis methods such Seurat and Monocle employ algorithms which compares one cluster all rest select markers according statistical tests. This pattern brings redundant calculations thus, results in low calculation efficiency, specificity accuracy. To...
Abstract We introduce starTracer, a novel R package designed to enhance the specificity and efficiency of marker gene identification in single-cell RNA-seq data analysis. The consists two primary functional modules: “searchMarker” “filterMarker”. module, operating as an independent pipeline, exhibits superior flexibility by accepting variety input file types. Its output is matrix, where genes are sorted their potential function cluster-specific markers, with those exhibiting greatest...