Lianxin Li

ORCID: 0000-0003-4504-3541
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Research Areas
  • Metal and Thin Film Mechanics
  • ZnO doping and properties
  • Shoulder and Clavicle Injuries
  • Advanced Nanomaterials in Catalysis
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Shoulder Injury and Treatment
  • Advanced Surface Polishing Techniques
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • GaN-based semiconductor devices and materials
  • Diamond and Carbon-based Materials Research
  • Cancer-related molecular mechanisms research
  • Gut microbiota and health
  • Intermetallics and Advanced Alloy Properties
  • Advanced biosensing and bioanalysis techniques
  • MicroRNA in disease regulation
  • Catalytic Processes in Materials Science
  • Alzheimer's disease research and treatments
  • Silicon and Solar Cell Technologies
  • Fluoride Effects and Removal
  • Graphene and Nanomaterials Applications
  • Semiconductor materials and devices
  • Trauma Management and Diagnosis
  • Carbon and Quantum Dots Applications
  • nanoparticles nucleation surface interactions
  • Acupuncture Treatment Research Studies

Shandong Provincial Hospital
2007-2025

Shandong First Medical University
2020-2025

First Affiliated Hospital of Soochow University
2025

Soochow University
2025

Guizhou University
2019-2024

Jiangsu University
2023-2024

Shandong Mental Health Center
2024

Anhui Medical University
2021-2023

Second Hospital of Anhui Medical University
2021-2023

Sichuan Agricultural University
2020-2023

The regulation of peroxymonosulfate (PMS) activation by photo-assisted heterogeneous catalysis is under in-depth investigation with potential as a replaceable advanced oxidation process in water purification, yet it remains significant challenge. Herein, we demonstrate strategy to construct polyethylene glycol (PEG) well-coupled dual-defect V

10.1002/anie.202419680 article EN Angewandte Chemie International Edition 2024-11-15

Fluoride is a common contaminant of groundwater and agricultural commodity, which poses challenges to animal human health. A wealth research has demonstrated its detrimental effects on intestinal mucosal integrity; however, the underlying mechanisms remain obscure. This study aimed investigate role cytoskeleton in fluoride-induced barrier dysfunction. After sodium fluoride (NaF) treatment cultured Caco-2 cells, both cytotoxicity cytomorphological changes (internal vacuoles or massive...

10.1016/j.ecoenv.2023.114940 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2023-04-24

The complex pathological mechanism of Alzheimer's disease (AD) limits the efficacy simple drug therapy, and drugs are difficult to penetrate blood-brain barrier (BBB). Therefore, it is a breakthrough enhance therapeutic effect AD by rationally using multiple strategies inhibit targets. In this study, macrophage membrane (MM) with active targeting inflammation function used functionalize molybdenum disulfide quantum dots (MoS

10.1002/adhm.202303211 article EN Advanced Healthcare Materials 2023-11-10

Patients with osteoporosis face challenges such as decreased bone density, a sparse trabecular structure, weakened osteogenic ability, and impaired angiogenesis, leading to poor osseointegration implant failure. Surface modification of implants biologically active molecules possessing various functions is an effective strategy improve osseointegration. In this study, we constructed simple multifunctional coating interface that significantly improves brief, was by coupling the Rgd adhesive...

10.1016/j.mtbio.2024.101150 article EN cc-by-nc-nd Materials Today Bio 2024-07-14

Though the underlying mechanism remains elusive, a close relationship between psychological stress and intestinal inflammation has been widely accepted. Such link is very important to set basis for our understanding of critical role gut-brain axis (GBA) in homeostatic processes health disease. Probiotics that could confer benefits mental through GBA are referred as “psychobiotics”. This study aimed further determine whether potential psychobiotic strain, Lactobacillus johnsonii BS15 prevent...

10.3389/fphar.2021.662148 article EN cc-by Frontiers in Pharmacology 2021-05-26

Abstract Background The long-term nonunion of bone defects is always a difficult problem in orthopaedics treatment. Artificial implants made polymeric materials are expected to solve this due their suitable degradation rate and good biocompatibility. However, the lack mechanical strength, low osteogenic induction ability poor hydrophilicity these synthetic limit large-scale clinical application. Results In study, we used bioactive glass (BG) (20%, W/W) polycaprolactone (PCL, 80%, as raw...

10.1186/s13036-023-00401-4 article EN cc-by Journal of Biological Engineering 2024-01-02

Defective diabetic wound healing is a major clinical challenge, where hyperglycemia at the site induces excessive reactive oxygen species (ROS) which activate MAPK pathway (particularly p38 MAPK), resulting in sustained release of inflammatory factors and cellular damage/apoptosis. Polyphenols are efficient ROS scavengers reduce level inflammation promote healing, but low bioavailability limits their biomedical application. This study developed simple highly method for preparing...

10.1016/j.mtbio.2025.101467 article EN cc-by-nc Materials Today Bio 2025-01-08

Porous cerium-doped manganese oxides have been facilely synthesized with dopamine and exhibit prominent activity humidity tolerance for O<sub>3</sub> decomposition.

10.1039/d0cy00196a article EN Catalysis Science & Technology 2020-01-01

For ozone decomposition, ultrathin δ-MnO<sub>2</sub> nanosheets were synthesized and the properties of oxygen vacancies regulated. The as-synthesized catalyst exhibited superior activity.

10.1039/d1en00149c article EN Environmental Science Nano 2021-01-01

Fluoride which is widespread in our environment and food due to its geological origin industrial pollution has been identified as a developmental neurotoxicant. Gut-brain axis provides new insight into brain-derived injury. We previously found the psychoactive effects of probiotic strain, Lactobacillus johnsonii BS15 against fluoride-induced memory dysfunction mice by modulating gut-brain axis. In this study, we aimed detect link between reconstruction gut microbiota through alleviate...

10.1016/j.ecoenv.2021.112108 article EN cc-by-nc-nd Ecotoxicology and Environmental Safety 2021-03-31

The complex biological process of osseointegration and the bio-inertness bone implants are major reasons for high failure rate long-term implants, have also promoted rapid development multifunctional implant coatings in recent years. Herein, through special design peptides, we use layer-by-layer assembly technology to simultaneously display two peptides with different functions on surface address this issue. A variety characterization techniques (ellipsometry, atomic force microscopy,...

10.1016/j.mtbio.2024.101108 article EN cc-by-nc Materials Today Bio 2024-06-04

Pyroptosis, a form of programmed cell death, that plays significant role in the occurrence and progression tumors, has been frequently investigated recently. However, prognostic significance therapeutic value pyroptosis glioma remain undetermined. In this research, we revealed relationship pyroptosis-related genes to by analyzing whole transcriptome data from The Cancer Genome Atlas (TCGA) dataset serving as training set Chinese Glioma (CGGA) validation set. We identified two subgroups...

10.3389/fonc.2022.717926 article EN cc-by Frontiers in Oncology 2022-03-31

Functional gradient materials (FGMs) are a category of advanced that contain two (or more) different components with continuously varying compositional distributions. With the advancement in nanotechnology, FGM applications have evolved from traditional to complex micro- and nano-electronic energy conversion devices. Therefore, studying mechanical behavior nanostructures FGMs plays crucial role determining feasibility their various applications. Herein, shear deformation Ti–Al nano-bulks...

10.1016/j.jmrt.2023.01.016 article EN cc-by-nc-nd Journal of Materials Research and Technology 2023-01-05

Super-enhancers (SEs), driving high-level expression of genes with tumor-promoting functions, have been investigated recently. However, the roles super-enhancer-associated lncRNAs (SE-lncRNAs) in tumors remain undetermined, especially gliomas. We here established a SE-lncRNAs expression-based prognostic signature to choose effective treatment glioma and identify novel therapeutic target.Combined analysis RNA sequencing (RNA-seq) data ChIP (ChIP-seq) patient-derived stem cells (GSCs) screened...

10.1186/s40246-023-00480-w article EN cc-by Human Genomics 2023-03-31

Understanding the formation mechanism of gallium nitride (GaN) crystals in different crystal orientations to optimize quality and improve device performance is important achieving high-performance devices. Despite significant advances experimental techniques study microstructure anisotropic differences during semiconductor growth, it still difficult dynamically observe evolution GaN growth at atomic level. In this paper, induced are investigated by means molecular dynamics simulations. The...

10.1021/acs.cgd.3c00701 article EN Crystal Growth & Design 2023-08-07

Gallium nitride (GaN) is frequently used as the primary material for manufacturing high-brightness light-emitting diodes (LEDs). Recently, atomic layer deposition has become increasingly prevalent across microelectronics, optoelectronics, and nanotechnology a method thin-film growth. Gaining insights into process of growth can significantly enhance device performance. Herein, molecular dynamics was to simulate GaN thin film on substrates with different patterned surfaces. Results showed that...

10.1021/acs.cgd.4c00001 article EN Crystal Growth & Design 2024-03-06
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