- Sexual function and dysfunction studies
- Epigenetics and DNA Methylation
- Hormonal and reproductive studies
- Cancer, Hypoxia, and Metabolism
- S100 Proteins and Annexins
- Mesenchymal stem cell research
- Adrenal and Paraganglionic Tumors
- Sexual Differentiation and Disorders
- Bladder and Urothelial Cancer Treatments
- Neuroblastoma Research and Treatments
- Kruppel-like factors research
- Metabolism, Diabetes, and Cancer
- Additive Manufacturing and 3D Printing Technologies
- Tryptophan and brain disorders
- Urinary and Genital Oncology Studies
- Prostate Cancer Treatment and Research
- Textile materials and evaluations
- Genital Health and Disease
- Reproductive System and Pregnancy
- Cancer, Lipids, and Metabolism
- Urinary Bladder and Prostate Research
- Hormonal Regulation and Hypertension
- Food Drying and Modeling
Sun Yat-sen University
2017-2023
Third Affiliated Hospital of Sun Yat-sen University
2017-2023
Yidu Central Hospital of Weifang
2019
Twin Cities Orthopedics
1999
University of Minnesota
1999
Glucose transporter 1 (GLUT1) plays a critical role in tumorigenesis and tumor progression multiple cancer types. However, the specific function clinical significance of GLUT1 prostate (PCa) are still unclear. Therefore, this study, we investigated PCa.GLUT1 protein levels tissue tumor-adjacent normal tissues were measured compared. Furthermore, real-time PCR Western blot analysis both used to detect expression different PCa cell lines. Flow cytometry cell-based assays, such as glucose...
Abstract Background Aging is one of the dominant factors contributing to erectile dysfunction (ED), and effective treatments for age-associated ED are urgently demanded. In this study, therapeutic efficiency bone marrow-derived mesenchymal stem cells (BMSCs) overexpressing microRNA-145 (miR-145) was evaluated in ED. Methods Sixty male Sprague-Dawley rats (24 months old) were randomly divided into 4 treatment groups ( n = 15/group): PBS (control), BMSCs, BMSCs transfected with a blank vector...
Aging has been deemed the primary factor in erectile dysfunction (ED). Herein, age-related changes response and histomorphology were detected, relationship between aging ED was investigated based on gene expression levels. Thirty male Sprague–Dawley (SD) rats randomly divided into 6 groups, intracavernous pressure (ICP) mean arterial (MAP) measured. Subsequently, corpus cavernosum (CC) harvested prepared for histological examinations of apoptosis, oxidative stress (OS), fibrosis. Then,...
BACKGROUND Bladder cancer is the fourth most common worldwide. Thyroid receptor-interacting protein 13 (TRIP13) a member of AAA+ ATPase family. The upregulation TRIP13 has been shown to be involved in few diseases, especially cancers, but expression and function bladder still elusive. MATERIAL AND METHODS In our study, was investigated with immunohistochemistry (IHC). mRNAs adjacent normal tissues were compared using quantitative real-time polymerase chain reaction (qRT-PCR) IHC scores....
The poor retention and ambiguous differentiation of stem cells (SCs) within corpus cavernosum (CC) limit the cell application in erectile dysfunction (ED). Herein, effects mechanism
Objective To evaluate the clinical characteristics, diagnosis and treatment of adrenal ganglioneuroma. Methods The data 8 cases ganglioneuromas at our hospital were reviewed retrospectively. Amang these cases, 5 tumors located in right side while 3 left side. The age was 26 to 67 years old.The mean tumor size 5.0 cm, ranged from 2.5 cm 9.7 cm. Results Among 6 performed laparoscopic adrenalectomy successfully. other two followed up without surgical intervention. operative time...
You have accessJournal of UrologyStem Cell Research: Stem Research II1 Apr 2018MP81-18 INTRACAVERNOUS INJECTION OF BONE MARROW MESENCHYMAL STEM CELLS MODIFIED WITH PDE5-RNAI IMPROVES ERECTILE DYSFUNCTION IN AGED RATS Hengjun Xiao, Weixin Yan, Yubin Cui, Jun Chen, and Liaoyuan Li XiaoHengjun Xiao More articles by this author , YanWeixin Yan CuiYubin Cui ChenJun Chen LiLiaoyuan View All Author Informationhttps://doi.org/10.1016/j.juro.2018.02.2726AboutPDF ToolsAdd to favoritesDownload...
Background: The penile corpus cavernosum is a critical tissue, serving as prerequisite for maintaining normal erection during sexual intercourse. pathological changes of are significantly associated with erectile dysfunction (ED), whose prevalence increases pronouncedly age. However, the cellular composition and molecular aging remain unclear.Methods: To map single-cell transcriptomic landscape aging, we performed uniform manifold approximation projection (UMAP), differential gene expression...