A5033753920- Rheumatoid Arthritis Research and Therapies
- Oral microbiology and periodontitis research
- Autoimmune and Inflammatory Disorders Research
- Musculoskeletal Disorders and Rehabilitation
- Systemic Lupus Erythematosus Research
- Laser Applications in Dentistry and Medicine
- Periodontal Regeneration and Treatments
- COVID-19 Clinical Research Studies
- Spondyloarthritis Studies and Treatments
- SARS-CoV-2 and COVID-19 Research
- Cervical Cancer and HPV Research
- Hepatitis C virus research
- Sarcoidosis and Beryllium Toxicity Research
- Osteomyelitis and Bone Disorders Research
- Medical and Biological Ozone Research
- Vasculitis and related conditions
- Infectious Diseases and Tuberculosis
- Salivary Gland Tumors Diagnosis and Treatment
- Food Safety and Hygiene
- Ear and Head Tumors
- Ovarian cancer diagnosis and treatment
- Bone and Joint Diseases
- Nutrition, Genetics, and Disease
- Autoimmune Bullous Skin Diseases
- Gout, Hyperuricemia, Uric Acid
Datta Meghe Institute of Medical Sciences
2022-2024
Manchester University NHS Foundation Trust
2023
Versus Arthritis
2023
University of Manchester
2023
Government Medical College
2019-2023
NIHR Manchester Biomedical Research Centre
2023
Manchester Academic Health Science Centre
2023
West Suffolk NHS Foundation Trust
2013-2023
West Suffolk Hospital
2013-2017
Suffolk University
2015
BackgroundFrom early in the COVID-19 pandemic, evidence suggested a role for cytokine dysregulation and complement activation severe disease. In TACTIC-R trial, we evaluated efficacy safety of baricitinib, an inhibitor Janus kinase 1 (JAK1) JAK2, ravulizumab, monoclonal C5 activation, as adjunct to standard care treatment adult patients hospitalised with COVID-19.MethodsTACTIC-R was phase 4, randomised, parallel-arm, open-label platform trial that undertaken UK urgent public health...
Gingival hyperpigmentation can be defined as a darker gingival colour beyond what is normally expected. The of the gingiva vital for facial beauty and contributes in great manner to appearance an aesthetic confident smile. A dark have negative psychological impact, particularly when combined with higher lip line or smile visible gingiva. gold standard managing pigmentation by scalpel surgical technique, despite its disadvantage resulting open wound that requires special care dressing....
<sec> <title>BACKGROUND</title> Gingival recession and periodontal pockets are the results of gradual deterioration alveolar bone ligament caused by periodontitis, which is inflammation tissues supporting tooth. The primary goal therapy to eradicate these aberrant traits. Despite being a popular treatment, SRP has limitations, such as difficulty accessing deeper root concavities. </sec> <title>OBJECTIVE</title> 1. To compare reduction in probing depth following scaling planing (SRP) with...
<sec> <title>BACKGROUND</title> When the teeth's attachment system is lost due to periodontal disorders, especially periodontitis, osseous abnormalities, extensive pockets, and tooth mobility result. Patients experience both practical aesthetic issues as a result of these impairments. Restoring attachment, which includes cementum, ligament, alveolar bone, primary objective regeneration therapy. Regenerative therapy approaches can be very helpful for infrabony deficiencies, one prevalent...
We evaluated the impact of clinic-based musculoskeletal ultrasonography (MSUS) on diagnosis and management cases as seen in day-to-day rheumatology practice. Data were retrieved for demography, background condition, clinical findings, indications, regions scanned, outcomes MSUS, categorised as: new-patients follow-up. New-patient records analysed to whether MSUS had helped confirm or change was no additional help. In follow-ups, we determined disease assessment, detection co-existing...
We evaluated the impact of clinic-based musculoskeletal ultrasonography (MSUS) on diagnosis and management cases as seen in day-to-day rheumatology practice. Data were retrieved for demography, background condition, clinical findings, indications, regions scanned, outcomes MSUS, categorised as: new-patients follow-up. New-patient records analysed to whether MSUS had helped confirm or change was no additional help. In follow-ups, we determined disease assessment, detection co-existing...
Abstract Background The aim was to describe the population of patients with moderate rheumatoid arthritis (RA) in United Kingdom and burden disease from perspectives patient, caregiver, health service. Methods In this descriptive study, retrospective patient-level data were extracted hospital medical records assess healthcare resource utilisation validated outcome measures administered via questionnaire RA (Disease Activity Score [DAS28] between 3.2 5.1) eight secondary care centres, their...
Abstract Objectives Interventions aimed at increasing TNF-α inhibitor serum drug levels (SDLs) may improve treatment response; however, previous studies suggesting SDL cut-offs have not accounted for adherence. The aim of this study was to establish the relationship between adalimumab/certolizumab SDLs and EULAR good vs non-/moderate response define associated with in fully adherent patients. Methods In a prospective observational study, 475 patients RA were treated certolizumab (n = 192) or...
To investigate the association between socioeconomic deprivation and outcomes following TNF inhibitor (TNFi) treatment.
We present two cases of ichthyosiform erythroderma associated with severe bilateral genu valgum. Other musculoskeletal features this condition are described. The details and outcome operative intervention for the correction deformities discussed. disturbances metabolism vitamin D medical management A review literature is presented.
Abstract Background: Nursing student’s dental health education model is aimed at orienting nursing students with oral knowledge so that these must be knowledgeable about to implement it in their daily practices, and thus, they can play a vital part serve as the ideal role for patients community. Therefore, questionnaire-based survey conducted assess knowledge, attitude, practices related among Sawangi, Wardha, Maharashtra, India. Materials Methods: Around 440 will participating...
Ensuring the health of gums and supporting structures (periodontium) is crucial during dental restoration procedures to achieve optimal function appearance teeth. Understanding anatomy, impact restorative materials, their interaction with periodontium essential for successful treatment outcomes. Crown lengthening a surgical procedure that involves removal gingiva bone tissue expose more tooth structure, thereby increasing visible portion (clinical crown height). To protect wound from...
Background: During COVID-19 all the tertiary institutes were overburdened so peripheral institutes, mostly district hospitals made functional to provide management patients in moderate and severe cases. The study attempts find out clinical profile of admitted one hospital. Methods: Retrospective data was studied from records hospital Samba when it chosen as dedicated Results: Record 77 analyzed with help descriptive statistics. Chi square test done association. Mean age 56.8±16.19 years male...
Rheumatoid arthritis (RA), psoriatic arthritis, and ankylosing spondylitis are highly prevalent inflammatory arthritides. Various conventional therapies currently in use, biologic have also been introduced into the treatment armamentarium. Despite remarkable efficacy of anti-tumor necrosis factor (TNF) agents, there still remains an unmet need for newer anti-TNF agents. A substantial number patients do not respond to initial agent, but may a second one. The modes administration marketed...