A5023569512- Phytoestrogen effects and research
- Phytochemical compounds biological activities
- Natural product bioactivities and synthesis
- Estrogen and related hormone effects
- Medicinal Plants and Neuroprotection
- Traditional and Medicinal Uses of Annonaceae
- Plant tissue culture and regeneration
- Neuroinflammation and Neurodegeneration Mechanisms
- Cocoa and Sweet Potato Agronomy
- Protein Hydrolysis and Bioactive Peptides
- Monoclonal and Polyclonal Antibodies Research
- Glycosylation and Glycoproteins Research
- Malaria Research and Control
- Pharmacological Effects of Natural Compounds
- Phytochemistry and Biological Activities
- Catalysis for Biomass Conversion
- Plant-derived Lignans Synthesis and Bioactivity
- Toxin Mechanisms and Immunotoxins
- NF-κB Signaling Pathways
- Bioactive Compounds and Antitumor Agents
- GABA and Rice Research
- Food Chemistry and Fat Analysis
- Polysaccharides and Plant Cell Walls
- Phytochemistry and Bioactivity Studies
- Tea Polyphenols and Effects
Ubon Ratchathani University
2015-2025
Khon Kaen University
2012
Ubon Ratchathani Rajabhat University
2010
The objective of this study was to obtain data on the distribution alkaloids in kratom plants grown Thailand. Two collections were performed, covering southern, central, and northern regions Thailand different seasons. contents alkaloids, including mitragynine (MG), paynantheine (PAY), speciogynine (SG), determined using validated HPLC method. 134 samples first collection collected from Nam Phu subdistrict, Ban Na San, Surat Thani, Thailand, during June October 2019 January 2020. maximum...
The bioactive compounds and anti-inflammatory properties of EL were preserved after honey treatment, indicating that honey-treated is a potential natural treatment for inflammatory conditions.
Diabetes mellitus, diagnosed as Madhumeho (sweet urine) in Thai traditional medicine, is believed to stem from imbalanced life elements. Ya That Opchoei mixture (YTO), a polyherbal mixture, used treat its symptoms. This study assessed the hypoglycemic potential of YTO and conducted qualitative quantitative analyses bioactive constituents. significantly inhibited α-glucosidase at IC 50 0.05 ± 0.00 mg/mL α-amylase activities 0.04±mg/mL. concentrations 2.22 increased C-peptide secretion...
Influence of elicitors on plumbagin accumulation in Drosera indica whole plant culture was investigated. Treatment plantlets with 150 mg/l chitosan and 100 μM salicylic acid mostly stimulated production after 3 days elicitation, while 0.5 mg/ml yeast extract 50 methyl jasmonate elicited at 6 days. Yeast (0.5 mg/ml) the most efficient elicitor to enhance (2.69±0.03 mg/g dry wt.) by 5.4-fold over control (0.50±0.01 wt.). Present results indicated effectiveness elicitation in in vitro culture...
Daidzin and its aglycone daidzein are major pharmacologically active compounds of soybean (Glycine max), kudzu (Pueraria lobata), kwao kruea khao (P. mirifica). Pharmacological activities daidzin mediated by more potent metabolites equol; however, is the predominant compound found in these medicinal plants, efficacy safety equol depend on amount consumed.To develop a specific monoclonal antibody (MAb)-based indirect competitive enzyme-linked immunosorbent assay (icELISA) for standardisation...
Coronavirus disease-2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, has become a pandemic and public health crisis. SARS-CoV-2 the seasonal common cold coronavirus (HCoV-OC43) belong to beta genus of human coronaviruses (HCoVs). In-cell ELISA assays were performed using HCoV-OC43 evaluated antiviral activity herbal plants. Eurycoma longifolia (EL) harmandiana (EH) roots (antipyretic properties) their constituent quassinoids, especially...
Abstract Miroestrol is a chromene with potent estrogenic activity present in Pueraria candollei, commonly known as White Kwao Krua. Although this compound only low amounts the plant, it plays an important role action of P. candollei products. As tool for further studies about efficacy and safety phytoestrogenic supplement, we generated novel monoclonal antibody against miroestrol. This anti-miroestrol was used to develop immunoassay determination miroestrol content, which can be quality...
Abstract Miroestrol (ME) is a potent phytoestrogen from the P. candollei tuberous root. It has been approved for use in clinical trials due to its beneficial effect on disorders associated with estrogen deficiency. To ensure medical efficacy and safety, high performance analytical methods ME analysis are required standardize products An enhanced chemiluminescence enzyme‐linked immunosorbent assay (ECL‐ELISA) was developed validated using polyclonal antibody against chemiluminescent system of...
Eurycoma longifolia Jack (EL) has been used for treating erectile dysfunction, in which inflammation plays a major role. EL tissue cultures can overcome the shortage of material; however, anti-inflammatory property such not investigated. Herein, we evaluated effects root and callus related species, harmandiana Pierre (EH), on lipopolysaccharide-activated RAW 264.7 cells. Eurycomalactone 9-methoxycanthin-6-one were predominant compounds calli. Eurycomanone content was 0.283 mg/g culture 0.348...
Asiaticoside (AS), the major active component of Centella asiatica (L.) Urban, is used as a memory enhancer and for wound healing. We have successfully prepared monoclonal antibodies (MAbs) against AS, developed an enzyme-linked immunosorbent assay (ELISA) system its determination. AS was conjugated to carrier protein bovine serum albumin (BSA), which acted immunogen. In order confirm immunogenicity, ratio hapten in AS-BSA conjugate determined by matrix-assisted laser desorption/ionization...
Pueraria candollei var. mirifica (PM) is a phytoestrogen-rich herb with rejuvenating qualities. Stability of chromenes, comprising deoxymiroestrol, miroestrol and isomiroestrol, in crude extract PM was investigated. The effects acid-base condition temperature on stability the chromene standard solution were analysed using gradient HPLC. degradation chromenes sensitive to high temperatures strongly acidic or alkaline solutions. Specifically, which exhibited highest estrogenic activity, can be...
Abstract Eurycoma longifolia (EL) and harmandiana (EH) are natural medicinal plants belonging to the Simaroubaceae family, well‐known for their ability enhance male sexual performance. The present study investigated phosphodiesterase‐5 (PDE‐5) inhibitory activity of intact roots EL EH. Additionally, canthin‐6‐one alkaloids, β ‐carboline quassinoids were also screened PDE‐5 activity. We developed in vitro root callus cultures EH determine Our results indicated that which include...
Abstract Introduction Glycyrrhizin (GLY) and sennoside A (SA) are characteristic bioactive marker compounds of the Kampo medicine Daiokanzoto. Their accurate detection in blends Rhei rhizoma Glycyrrhizae radix several species (4:1 or 4:2) is essential for quality control to ensure therapeutic efficacy. rapid, efficient assay can significantly facilitate their detection. Objective To establish a rapid qualitative GLY SA detection, lateral flow immunoassay (LFA) was developed using specific...