- Catalytic C–H Functionalization Methods
- Radical Photochemical Reactions
- Asymmetric Synthesis and Catalysis
- Cyclopropane Reaction Mechanisms
- Sulfur-Based Synthesis Techniques
- Oxidative Organic Chemistry Reactions
- Nanoplatforms for cancer theranostics
- Renal Diseases and Glomerulopathies
- Remote Sensing and Land Use
- Advanced Proteomics Techniques and Applications
- Glycosylation and Glycoproteins Research
- Berberine and alkaloids research
- Click Chemistry and Applications
- biodegradable polymer synthesis and properties
- Advanced Polymer Synthesis and Characterization
- Metal-Organic Frameworks: Synthesis and Applications
- Chemical Synthesis and Analysis
- Antimicrobial Peptides and Activities
- Multicomponent Synthesis of Heterocycles
- Chemical synthesis and alkaloids
- Synthesis and Biological Activity
- Polymer crystallization and properties
- Biochemical and Structural Characterization
- Cholinesterase and Neurodegenerative Diseases
- Advanced Nanomaterials in Catalysis
Wuhan University
2016-2022
State Key Laboratory of Information Engineering in Surveying Mapping and Remote Sensing
2022
West Anhui University
2022
Shenzhen Institute for Drug Control
2020
Shanghai University
2019
EarthTech International (United States)
2016
Northeast Agricultural University
2015
East China Normal University
2013-2014
Beijing University of Chemical Technology
2013
Sichuan University
2006
Both the urinary proteome and its glycoproteome can reflect human health status, more directly, functions of kidney tracts. Because high abundance protein albumin is not N-glycosylated, urine N-glycoprotein enrichment procedure could deplete it, thus provide a detailed profile in addition to glycosylation information especially when albuminuria occurs some diseases. In terms describing details proteins, even better choice than itself. Pooled samples from healthy volunteers were collected...
Starting from tryptamine 4 and isatin 5, a biomimetic approach to the pentacyclic substructure 1 of perophoramidine communesin was developed. The key steps were create stable three/six bicyclic system 2 on 2,3-double bond an indole derivative 3 by intramolecular cyclopropanation, followed ring opening resulting cyclopropane with in situ generated amine group aniline.
Tetrahydrofuran is a privileged structural moiety in many important organic compounds. In this work, we have developed simple and mild catalytic oxidative amination of tetrahydrofuran mediated by visible-light catalysis. The C(sp3)-H bond was activated using molecular oxygen as benign oxidant. Besides, variety azoles could be tolerated, providing green route for N-substituted azoles.
A mild and catalytic oxidative Csp<sup>3</sup>–H activation of methyl aromatics using O<sub>2</sub><italic>via</italic> photocatalysis has been achieved. lot can be tolerated, providing a route for aromatic carboxylates. In addition, this protocol performed on gram scale.
An iron porphyrin-catalyzed three-component reaction of ethyl diazoacetate with aliphatic amines and β,γ-unsaturated α-keto esters is reported. The use porphyrin catalyst allows to be used as the substrate without encountering poisoning issue a series β-hydroxy-α-amino are produced in high yields excellent regioselectivities.
A palladium-catalyzed multicomponent reaction of alkynes, carboxylic acids, and isocyanides has been developed with the assistance silver salt under mild conditions. Highly functionalized captodative olefins are synthesized efficiently by this method, which can find many applications as versatile synthons in organic synthesis.
A fishing platform was developed using immobilized capillary enzyme reactors in combination with liquid chromatography-mass spectrometry (LC-MS) to fish acetylcholinesterase inhibitor (AChEI) from Mahonia bealei (Fort.) Carr. (M. bealei) extract. Four potential AChEIs (columbamine, jatrorrhizine, berberine, and palmatine) were successfully screened out identified. Their AChE inhibitory activities further verified by an vitro assay IC50 values of 0.93 ± 0.12 μg/mL (columbamine), 3.50 0.15...
In this paper, a new semantic change detection (CD) dataset based on Chinese Gaofen-2 (GF-2) satellite images with high spatial resolution (HSR) namely Wuhan Urban Semantic Understanding (WUSU) is built up and CD framework combining binary tasks deep learning conditional random field model (SDCRF) proposed. Existing datasets mostly focus “change/no change”. Traditional methods pay attention only either of the task or task. Although there are to handle both simultaneously but they ignore...
Abstract The structure of the product (IVd) is confirmed by X‐ray analysis.