Yuchao Chen

ORCID: 0009-0008-2582-7641
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About
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Research Areas
  • Microfluidic and Bio-sensing Technologies
  • Microfluidic and Capillary Electrophoresis Applications
  • Metallurgical Processes and Thermodynamics
  • Advanced Battery Materials and Technologies
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Iron and Steelmaking Processes
  • Electrowetting and Microfluidic Technologies
  • Advanced battery technologies research
  • Radiative Heat Transfer Studies
  • Combustion and flame dynamics
  • Welding Techniques and Residual Stresses
  • Membrane Separation and Gas Transport
  • Biosensors and Analytical Detection
  • Particle Dynamics in Fluid Flows
  • Electrocatalysts for Energy Conversion
  • Advancements in Battery Materials
  • Membrane Separation Technologies
  • Solar Thermal and Photovoltaic Systems
  • Wave and Wind Energy Systems
  • Nanopore and Nanochannel Transport Studies
  • Solar-Powered Water Purification Methods
  • Advanced Photocatalysis Techniques
  • Heat Transfer and Boiling Studies
  • Aerosol Filtration and Electrostatic Precipitation
  • Electrical Fault Detection and Protection

Jinan University
2024

Southern University of Science and Technology
2024

Cornell University
2023-2024

Ningbo University
2021-2024

Zhejiang University of Technology
2022-2024

Institute of Mechanics
2024

Chinese Academy of Sciences
2024

Purdue University Northwest
2016-2023

Center for Innovation
2018-2023

Tsinghua University
2020-2023

Significance The separation and analysis of circulating tumor cells (CTCs) provides physicians a minimally invasive way to monitor the response cancer patients various treatments. Among existing cell-separation methods, acoustic-based approaches provide significant potential preserve phenotypic genotypic characteristics sorted cells, owing their safe, label-free, contactless nature. In this work, we report development an device that successfully demonstrates isolation rare CTCs from clinical...

10.1073/pnas.1504484112 article EN Proceedings of the National Academy of Sciences 2015-04-06

Significance We present 3D acoustic tweezers, which can trap and manipulate single cells particles along three mutually orthogonal axes of motion by recourse to surface waves. use tweezers pick up cells, or entire cell assemblies, deliver them desired locations create 2D patterns, print the into complex shapes. This technology is thus shown offer better performance over prior manipulation techniques in terms both accurate precise a noninvasive, label-free, contactless manner. method offers...

10.1073/pnas.1524813113 article EN Proceedings of the National Academy of Sciences 2016-01-25

Significance We have developed a unique approach for the separation of particles and biological cells through standing surface acoustic waves oriented at an optimum angle to fluid flow direction in microfluidic device. This experimental setup, optimized by systematic analyses, has been used demonstrate effective based on size, compressibility, mechanical properties cells. The potential this method biological–biomedical applications was demonstrated example isolating MCF-7 breast cancer from...

10.1073/pnas.1413325111 article EN Proceedings of the National Academy of Sciences 2014-08-25

Rapid and homogeneous mixing inside a microfluidic channel is demonstrated via the acoustic streaming phenomenon induced by oscillation of sidewall sharp-edges. By optimizing design sharp-edges, excellent performance fast speed can be achieved in simple device, making our sharp-edge-based micromixer promising candidate for wide variety applications.

10.1039/c3lc50568e article EN Lab on a Chip 2013-01-01

Although aqueous zinc-ion batteries (ZIBs) are promising for scalable energy storage application, the actual performance of ZIBs is hampered by irreversibility. Optimization electrolyte composition a relatively practical and facile way to improve coulombic efficiency (CE) Zn plating/stripping reversibility ZIBs. N,N-Dimethylacetamide (DMA) has higher Gutmann donor number (DN) than that H2 O, abundant polar groups, economic price. Herein, mixture containing 10 vol% DMA ZnSO4 , which an...

10.1002/smll.202202363 article EN Small 2022-06-06

A highly reliable, programmable, and cost-effective acoustofluidic pump is demonstrated utilizing the acoustic streaming effects generated by oscillation of tilted sharp-edge structures.

10.1039/c4lc00806e article EN Lab on a Chip 2014-01-01

The emerging field of droplet microfluidics requires effective on-chip handling and sorting droplets. In this work, we demonstrate a microfluidic device that is capable picoliter water-in-oil droplets into multiple outputs using standing surface acoustic waves (SSAW). This integrates single-layer channel with interdigital transducers (IDTs) to achieve generation sorting. Within the SSAW field, experience an radiation force are pushed toward pressure node. As result, by tuning frequency...

10.1021/ac400548d article EN Analytical Chemistry 2013-05-06

We developed a standing surface acoustic wave (SSAW)-based cell sorting device. The throughput of our device has been significantly improved by using focused interdigital transducers (FIDTs) as SSAW generator.

10.1039/c5lc00706b article EN Lab on a Chip 2015-01-01

The separation of nanoscale particles based on their differences in size is an essential technique to the nanoscience and nanotechnology community. Here, nanoparticles are successfully separated a continuous flow by using tilted‐angle standing surface acoustic waves. field deflects volume, fractionation optimized tuning cutoff parameters. nanoparticlesis demonstrated with ≈90% recovery rate. nanoparticle method versatile, non‐invasive, simple.

10.1002/adfm.201606039 article EN Advanced Functional Materials 2017-03-03

An acoustic separation device that can achieve high-throughput, high-efficiency, and non-invasive platelet enrichment from undiluted whole blood.

10.1039/c6lc00682e article EN Lab on a Chip 2016-01-01

A microfluidic cytometer is demonstrated<italic>via</italic>the standing surface acoustic wave (SSAW)-based 3D cell focusing. This SSAW-based flow allows precise cytometry with the advantages of sheathless focusing, bio-compatibility, simple and compact device, significantly reduced biohazards.

10.1039/c3lc51139a article EN Lab on a Chip 2014-01-01

Microfluidic fluorescence-activated cell sorters (μFACS) have attracted considerable interest because of their ability to identify and separate cells in inexpensive biosafe ways. Here a high-performance μFACS is presented by integrating standing surface acoustic wave (SSAW)-based, 3D cell-focusing unit, an in-plane fluorescent detection SSAW-based cell-deflection unit on single chip. Without using sheath flow or precise rate control, the technique can focus into file at designated position....

10.1002/smll.201801996 article EN Small 2018-08-31

Cell/bead washing is an indispensable sample preparation procedure used in various cell studies and analytical processes. In this article, we report a standing surface acoustic wave (SSAW)-based microfluidic device for bead continuous flow. our approach, the radiation force generated SSAW field utilized to actively extract cells or beads from their original medium. A unique configuration of tilted-angle (taSSAW) employed device, enabling us wash with >98% recovery rate >97% efficiency. We...

10.1039/c4lc00903g article EN Lab on a Chip 2014-11-05

Non-contact, continuous enrichment of low-abundance cell samples in microfluidics is demonstrated<italic>via</italic>the standing surface acoustic waves (SSAW).

10.1039/c3lc51001h article EN Lab on a Chip 2014-01-01

We numerically and experimentally investigate the acoustophoresis of microparticles in standing surface acoustic wave microfluidic devices.

10.1039/c5lc00707k article EN Lab on a Chip 2015-12-24

The first microfluidic-based on-chip sputum-liquefaction device is demonstrated <italic>via</italic> an acoustofluidic micromixer.

10.1039/c5lc00539f article EN Lab on a Chip 2015-01-01

We present an ultra-compact spectrometer that uses a 10×10 hole array as the dispersive component. Our analysis shows two-dimensional intensity distribution can be modeled by system of simultaneous linear equations when size each in component has been pre-designed appropriately. One readily recover spectral contents input radiation solving equation with regularized procedure. Experimental results show reconstruction range is at least within entire visible band, which further extended if...

10.1364/ol.40.003217 article EN Optics Letters 2015-07-01

An active, spatiotemporally controllable chemical gradient generator is demonstrated utilizing the acoustic streaming effects induced by acoustically oscillating sharp-edge structures.

10.1039/c5lc00868a article EN Lab on a Chip 2015-01-01
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