A5101746364- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Energy and Environment Impacts
- Urban Green Space and Health
- Effects and risks of endocrine disrupting chemicals
- Urban Heat Island Mitigation
- Health, Environment, Cognitive Aging
- Pesticide Exposure and Toxicity
- Urban Transport and Accessibility
- Toxic Organic Pollutants Impact
- Energy, Environment, and Transportation Policies
- Nutritional Studies and Diet
- Birth, Development, and Health
- Carcinogens and Genotoxicity Assessment
- Noise Effects and Management
- Air Quality Monitoring and Forecasting
- Regulation of Appetite and Obesity
- Obesity, Physical Activity, Diet
- Telomeres, Telomerase, and Senescence
- Pesticide Residue Analysis and Safety
- Metabolomics and Mass Spectrometry Studies
- Hormonal and reproductive studies
- Sleep and Work-Related Fatigue
- Land Use and Ecosystem Services
- Insect and Pesticide Research
Zhengzhou University
2015-2025
Huazhong University of Science and Technology
2012-2024
Ministry of Ecology and Environment
2015-2016
In-Q-Tel
2016
Exposure to bisphenol A (BPA), a monomer widely used manufacture polycarbonate plastics, has been reported be associated with abnormalities of liver function and hepatic damage. However, the molecular mechanism under pathogenesis injury is unclear. In this study, effect perinatal exposure BPA at reference dose 50 µg/kg/day on apoptotic index in rat offspring was investigated. Increased levels ALT enhanced cell apoptosis were observed 15 21 weeks, significantly increased activity caspase-3...
Long-term exposure to ambient air pollution and physical activity are linked metabolic syndrome (MetS). However, the joint effect of on MetS remains largely unknown in rural Chinese adult population. In this study, 39 089 individuals were included from Henan Rural Cohort study that recruited 259 at baseline. Participants' pollutants (including particulate matter with an aerodynamic diameter ≤ 1.0 µm (PM1), ≤2.5 (PM2.5), or 10 (PM10) nitrogen dioxide (NO2)) evaluated by using a spatiotemporal...
To evaluate the associations between long-term exposure to particulate matter with an aerodynamic diameter ≤1.0 μm and ≤2.5 (PM1 PM2.5), nitrogen dioxide (NO2) type 2 diabetes prevalence fasting blood glucose levels in Chinese rural populations.A total of 39, 259 participants were enrolled The Henan Rural Cohort study. Questionnaires medical examination conducted from July 2015 September 2017 areas province, China. Three-year average residential PM1, PM2.5, NO2 for each subject estimated by...
Poor sleep quality is associated with poor of life and may even lead to mental illnesses. Several studies have indicated the association between exposure air pollution quality. However, evidence very limited in China, especially rural areas. Participants this study were obtained from Henan Rural Cohort established during 2015–2017. Sleep was evaluated using Pittsburgh Quality Index (PSQI) baseline survey. defined by global score PSQI > 5. Participants' exposures PM2.5, PM10 (particulate...
Epidemiological studies on the association of residential greenness with sleep quality are limited in China. This study aims to investigate long-term exposure rural In our study, 27,654 residents were selected from 4 counties Henan Province by a multi-stage stratified cluster sampling method. Participants' was assessed using Pittsburgh Sleep Quality Index (PSQI). The Normalized Difference Vegetation (NDVI) and Enhanced (EVI), two satellite-derived vegetation indexes, used assess level...
Air pollution has been shown to be associated with blood lipid levels. However, studies on long-term ambient particulate matter aerodynamic diameter ≤1 μm (PM1) exposure in high-exposure areas are still limited. This study aimed explore the associations among PM1 exposure, lipids and dyslipidemias.Baseline data of The Henan Rural Cohort was used present study, including a total 39,259 participants aged from 18 79 years. Daily levels were estimated by spatiotemporal model using ground-level...
ABSTRACT Perfluorooctane sulfonate (PFOS) is a widespread environmental contaminant that detected in the lung of mammals. The mechanisms underlying PFOS‐induced cytotoxicity remain unclear. main purpose this study was to evaluate cytotoxic effects PFOS on human cancer A549 cells and its possible molecular mechanism. were treated with (0, 25, 50, 100 200 μ m ) cellular apoptosis, mitochondrial membrane potential as well intracellular reactive oxygen species determined. In study, induced...
Although long-term exposure to air pollution and physical inactivity are linked increased risk for atherosclerotic cardiovascular diseases (ASCVD), however, the interactive effect of activity (PA) on high 10-year ASCVD is largely unknown.A total 31,162 individuals aged 35-74 years were derived from Henan Rural Cohort Study, after with personal histories or missing data predictors excluded. Concentrations pollutants (nitrogen dioxide (NO2), particulate matter an aerodynamics diameters ≤ 1.0...
Although it has been reported that herbicides exposure is related to adverse outcomes, available evidence on the associations of quantitatively measured with type 2 diabetes mellitus (T2DM) and prediabetes still scant. Furthermore, effects mixtures T2DM remain unclear among Chinese rural population.To assess plasma population.A total 2626 participants were enrolled from Henan Rural Cohort Study. Plasma gas chromatography coupled triple quadrupole tandem mass spectrometry. Generalized linear...
In this study 3307 samples of 24 vegetables and fruits from 18 regions Henan Province, China, were collected in 2021 with the aim assessing levels pesticide residues analysing differences between different sources Province. Thirteen kinds pesticides analysed by gas chromatography-mass spectrometry (GC-MS) detection rates compared chi-square test. all samples, except ginger, pimento, edible fungi yam, detected. The difenoconazole, acetamiprid, carbendazim, procymidone, emamectin benzoate,...
BackgroundDepression and anxiety are top contributors to non-fatal health loss globally. Several studies have indicated the association between residential greenness mental health.MethodThe participants (n = 27,366) were recruited from four counties in Henan Province, China during 2015–2017. Symptoms of depression evaluated using Patient Health Questionnaire-2 (PHQ-2) Generalized Anxiety Disorder-2 (GAD-2) baseline survey. The level 3-year period before survey was assessed Moderate...
Population-based studies on the associations of long-term exposure to particulate matter (PM) with androgen and progesterone are still scant. Residential greenness is benefits health by promoting physical activity, reducing air pollution, improving mental health, but it remains unclear whether related levels among humans.This study aimed explore individual interactive effects PM residential serum testosterone rural Chinese adults.A total 6017 subjects were recruited from baseline Henan Rural...
Although exposure to ambient air pollution (AAP) increases the risk for arteriosclerotic cardiovascular disease (ASCVD), evidence on association of solid fuel use with ASCVD and its modified by remains limited.A total 16,779 adults were derived from Henan Rural Cohort Study. Concentrations pollutants (PM1, PM2.5, PM10, NO2) estimated a spatiotemporal model based satellites data. Solid was assessed self-reported questionnaire. The associations high 10-year explored using logistic regression...
The impact of organophosphate pesticide (OPP) exposure on osteoporosis in adult population remains unclear. Thus, it is necessary to explore the association between a mixture OPPs and prevalence as well identify major contributor this association. Participants were selected from 2005-2008 cycle NHANES cross-sectional study. OPP was estimated using six different metabolites found urine. Dual-energy X-ray absorptiometry (DXA) used measure bone mineral density (BMD). Survey-weighted generalized...
Background: Diet plays an important role in preventing and managing the progression from prediabetes to type 2 diabetes mellitus (T2DM). This study aims develop prediction models incorporating specific dietary indicators explore performance T2DM patients non-T2DM patients. Methods: retrospective was conducted on 2215 Henan Rural Cohort. The key variables were selected using univariate analysis least absolute shrinkage selection operator (LASSO). Multiple predictive constructed separately...
Introduction In recent years, industrial and agricultural advancements in Henan Province have increased heavy metal contamination rice, raising public concerns. The aim of this study was to investigate the levels five metals, cadmium (Cd), chromium (Cr), lead (Pb), mercury (Hg), inorganic arsenic (As), rice from assess potential health risks. Methods A total 6,632 samples were collected 18 regions between 2020 2022. analyzed for Cd, Cr, Pb, Hg, As using inductively coupled plasma mass...