A5024331174- Liver Disease Diagnosis and Treatment
- Breast Cancer Treatment Studies
- Ubiquitin and proteasome pathways
- Hedgehog Signaling Pathway Studies
- HER2/EGFR in Cancer Research
- Cancer and Skin Lesions
- Cancer-related molecular mechanisms research
- Liver physiology and pathology
- Birth, Development, and Health
- Ferroptosis and cancer prognosis
- Cancer-related Molecular Pathways
- Breast Lesions and Carcinomas
- Cancer Diagnosis and Treatment
- Parasites and Host Interactions
- Advanced battery technologies research
- Diet and metabolism studies
- Wnt/β-catenin signaling in development and cancer
- Cancer Mechanisms and Therapy
- RNA modifications and cancer
- Eosinophilic Disorders and Syndromes
- Trace Elements in Health
- MicroRNA in disease regulation
- Liver Disease and Transplantation
- Cancer Cells and Metastasis
- Remote Sensing and Land Use
First Hospital of Jiaxing
2015-2025
Jiaxing University
2015-2025
Anhui Medical University
2024
University of Malaya
2024
Nanjing University of Science and Technology
2021
University of Colorado Boulder
2019
Zhejiang University of Technology
2013
Breast cancer is one of the most common malignant diseases in women. The main cause death from breast its metastases at distant sites body. Interleukin-33 (IL-33) a cytokine IL-1 family and found overexpressed various cancers. aim present study was to explore association serum IL-33 sST2 with cancer. Here, levels were significantly higher patients than healthy volunteers. Serum vascular endothelial growth factor (VEGF), metalloproteinase-11 (MMP-11), platelet-derived factor-C (PDGF-C) also...
Residual host cell DNA in biological products poses potential risks of tumorigenicity and infectivity. Therefore, current regulatory authorities including the World Health Organization (WHO), Chinese Pharmacopoeia, U.S. Food Drug Administration (FDA) have limited acceptance amounts residual (less than 10 ng or 3 ng/dose). Among various detection methods for DNA, quantitative PCR (qPCR) is recognized as most practical method its high sensitivity, accuracy, precision, efficiency. This study...
Di-(2-ethylhexyl)-phthalate (DEHP), as distinctive endocrine disrupting chemicals, has become a global environmental pollutant harmful to human and animal health. However, the impacts on offspring mothers with maternal DEHP exposure are largely unknown mechanism remains elusive. We established DEHP-exposed mice investigate mother illustrate from multiple perspectives. Pregnant were administered different doses of DEHP, respectively. Metagenomic sequencing used fecal transcriptome using...
Roof plate-specific spondin (RSPO) proteins are potent Wnt pathway agonists and involve in a broad range of developmental physiological processes. This study investigated the activities mechanisms RSPOs liver fibrogenesis, especially hepatic stellate cell (HSC) activation. HSC activation was assessed by fibrosis biomarker (α-smooth muscle actin Collagen-I), phenotypic change (accumulation lipid droplets), increased proliferation. Similarly, activity evaluated expression nuclear β-catenin T...
Ductal carcinoma in situ with microinvasion (DCISM) was defined as one or more foci of invasion beyond the basement membrane within 1 mm. The size primary lesion is associated axillary status and prognosis patients invasive breast cancer; thus, it interest to determine whether multiple are a higher risk positive worse long-term outcomes DCISM.This study identified 359 DCISM who had undergone evaluation at our institute from January 2006 December 2015. Patients were categorized focus (≥2...
The assembly and testing of a rechargeable 3 V lithium-ion battery in the common 2032 coin cell format is demonstrated classroom environment without use expensive complex air-free equipment. procedure has been developed to eliminate highly toxic materials flammable solvents, can be accomplished 15 min, designed as inexpensive, safe, simple possible. repeatedly charged with cheap USB-powered charger used power an LED tea candle or similar device. A stopwatch multimeter estimate capacity...
Hepatocellular carcinoma (HCC) is a leading cause of malignant disease-associated mortality, particularly in China. The RSPO2 (R‑spondin 2) gene evolutionarily conserved vertebrates and involved developmental physiological processes. Importantly, has been reported to be associated with colon cancer potentiate the Wnt/β‑catenin signaling pathway. In present study, enhanced expression HCC was observed using tissue microarray. Similarly, level higher HepG2, Huh7 Hep3B cells but lower Bel7404...
Sclerosing extramedullary hematopoietic tumor (SEMHT) is a rare that can occur in association with some chronic myeloproliferative neoplasms, particularly myelofibrosis. The morphology of SEMHT mimic wide variety other lesions, both macroscopically and microscopically. originating from the colon extremely rare. present study reports case involvement peri-intestinal lymph nodes. On basis clinical symptoms endoscopic results, malignant was suspected. Pathological examination revealed...
SCY1-like 1-binding protein 1 (SCYL1BP1) is a newly identified transcriptional activator domain containing with many unknown biological functions. Recently emerging evidence has revealed that it novel regulator of the p53 pathway, which very important for development human cancer. However, effects SCYL1BP1 on lung squamous carcinoma cell behavior remain poorly understood. In this study, we present can promote degradation MDM2 and further inhibit G1/S transition lines. Functional assays found...
Breast cancer has become a fatal disease for women world-wide. Its incidence in China been increasing yearly, and the identification of early-stage biomarkers is urgently required.ANOVA was carried out case primary tumor, adjacent normal tissue, tumor metastasis breast cancer, on pan-cancer samples using genome-wide methylation data 31 solid Illumina Methylation 450K chips downloaded from The Cancer Genome Atlas (TCGA) website September 2018. sites showing significant difference (P ≤ 0.05)...
Anomaly detection is a hot topic in hyperspectral data processing since no prior information about the target required. Meanwhile, multi-scale can improve performance. This paper proposes anomaly algorithm images based on sparse and low rank representation. Some pixels are randomly selected to construct dictionary, belonging large abnormal targets with high probability. Therefore, matrix dictionary constitute pure background component targets, contains noise smaller targets. Using recursive...
The IBCSG 23-01 and AMAROS trials both reported that axillary lymph node dissection (ALND) did not change survival rates in breast cancer patients with positive nodes detected by sentinel biopsy (SLNB). aim of this study was to determine whether mastectomy false-negative frozen section (FS) SLNB could forgo ALND. This a retrospective cN0 diagnosed primary invasive treated at our institute between January 2010 December 2014. Patients FS were separated the following management non-ALND group...
Background: Poland's Syndrome (PS) is a rare congenital syndrome characterized by the unilateral partial or complete absence of sternocostal head pectoralis major muscle and ipsilateral brachysyndactyly syndactyly fingers. It has been reported to be associated with other diseases, but PS accompanied neurofibroma rarely reported. Case Report: We report case 16-year-old man left breast PS. Physical examination showed mass in skin hyperpigmentation increased body hair. Intraoperative...