Mohit Malhotra

ORCID: 0009-0008-7531-3577
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About
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Research Areas
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Chronic Myeloid Leukemia Treatments
  • Macrophage Migration Inhibitory Factor
  • Structural Behavior of Reinforced Concrete
  • Immune cells in cancer
  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Network Traffic and Congestion Control
  • Acute Myeloid Leukemia Research
  • IPv6, Mobility, Handover, Networks, Security
  • Dysphagia Assessment and Management
  • Cytokine Signaling Pathways and Interactions
  • Immune Cell Function and Interaction
  • Ferroptosis and cancer prognosis
  • Esophageal and GI Pathology
  • Tracheal and airway disorders
  • Wireless Networks and Protocols
  • Mobile Agent-Based Network Management
  • Cancer Genomics and Diagnostics

Anthem Biosciences (India)
2024

Bhubaneswar Borooah Cancer Institute
2024

Centre for Development of Advanced Computing
2011-2012

Abstract Dynamic interactions within the tumor micro-environment drive patient response to immune checkpoint inhibitors. Existing preclinical models lack true representation of this complexity. Using a Head and Neck cancer derived TruTumor histoculture platform, spectrum 70 patients anti-PD1 treatment is investigated in study. With subset 55 samples, multiple assays characterize T-cell reinvigoration cytotoxicity are performed. Based on levels these two parameters, stratified into five...

10.1038/s41467-024-45723-z article EN cc-by Nature Communications 2024-02-21

Solid tumors are dense three-dimensional (3D) multicellular structures that enable efficient receptor-ligand trans interactions via close cell-cell contact. Immunoglobulin-like transcript (ILT)2 and ILT4 related immune-suppressive receptors play a role in the inhibition of myeloid cells within tumor microenvironment. The relative contribution ILT2 to immune context solid tissue has not been fully explored. We present evidence both contribute inhibition. found although inhibits cell...

10.1158/2326-6066.cir-23-0568 article EN Cancer Immunology Research 2024-02-23

Esophageal cancer is the sixth most common in India with a incidence of around 4.5%. Dysphagia primary manifestation advanced esophageal 80%-90% patients. one distressing and debilitating symptom for The use self-expanding metallic stents (SEMS) has revolutionized treatment dysphagia This study aims to assess role SEMS palliation patients cancer.

10.1155/ijso/3331040 article EN cc-by International Journal of Surgical Oncology 2024-01-01
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