A5077924626- Congenital Heart Disease Studies
- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Urinary Tract Infections Management
- Pediatric Urology and Nephrology Studies
- Cardiac Structural Anomalies and Repair
- Coronary Artery Anomalies
- Sphingolipid Metabolism and Signaling
- Bacterial Infections and Vaccines
- Infective Endocarditis Diagnosis and Management
- Heart Rate Variability and Autonomic Control
- Cardiovascular Syncope and Autonomic Disorders
- Molecular Biology Techniques and Applications
- Acute Kidney Injury Research
- Sepsis Diagnosis and Treatment
- Vascular anomalies and interventions
- Silicon Nanostructures and Photoluminescence
- Infectious Aortic and Vascular Conditions
- Acute Lymphoblastic Leukemia research
- Probiotics and Fermented Foods
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Vascular Procedures and Complications
- Erythrocyte Function and Pathophysiology
- Salivary Gland Disorders and Functions
- Fluid Dynamics and Heat Transfer
University of Tokyo Hospital
2013-2024
Stanford University
2024
National Cerebral and Cardiovascular Center
2019-2024
The University of Tokyo
2003-2021
Photonic Systems (United States)
2007
Hiroshima Institute of Technology
2007
Kurume Institute of Technology
2001
Abstract Background Sphingosine 1-phosphate (Sph-1-P), abundantly stored in platelets and released extracellularly upon activation, plays important roles as an extracellular mediator by interacting with specific cell surface receptors, especially the area of vascular biology immunology/hematology. Although plasma Sph-1-P level is reportedly determined red blood cells (RBCs), but not platelets, this may be true cases where have been substantially activated. Methods results We measured...
ObjectiveTo investigate the effect of graft sizing on valve performance in valve-sparing aortic root replacement for bicuspid valve.MethodsIn addition to a diseased control model, 3 representative groups—free-edge length aortic/graft diameter (FELAD) ratio <1.3, 1.5 1.64, and >1.7—were replicated explanted porcine roots (n = 3) using straight grafts sized respective native free-edge length. They were run validated ex vivo univentricular system under physiological parameters 20 cycles. All...
Urinalysis is one of the most common laboratory screening tests to detect problems in renal and urinary system; however, they cannot atypical cells (Atyp.Cs). The Sysmex UF-5000, a fully automated urine particle analyzer, can Atyp.Cs via its Atyp.C parameter. This study aimed compare clinical value parameter with that sediment microscopy. A total 471 leftover samples were submitted Department Clinical Laboratory at University Tokyo Hospital for urinalysis by manual microscopy examination...
This study aimed to elucidate the short-term surgical outcomes and hemodynamics of Intuity valve compared standard bioprosthesis in Japanese patients.
Abstract OBJECTIVES The goal of this study was to determine the long-term surgical outcomes patients with functional single ventricles associated heterotaxy syndrome, risk factors for mortality and Fontan stage completion. METHODS Overall, 279 a ventricle syndrome who underwent an initial procedure at our institute between 1978 2021 were grouped into 4 “eras” based on year during which performed: era 1 (1978–1989, n = 71), 2 (1990–1999, 98), 3 (2000–2009, 64) (2010–2021, 46). Neonatal...
Abstract Vasovagal syncope (VVS) is well-known to occur in patients undergoing phlebotomy, however, there have been no large-scale studies of the incidence VVS blood collection room. The aim our present retrospective study was investigate conditions phlebotomy and determine incidence/factors predisposing development VVS. We investigated 677,956 phlebotomies performed outpatients room, explore factors Our analysis revealed an overall 0.004% suggested that use more than 5 tubes a waiting time...
Objectives Biologically false positive (BFP) reactions are well described in early literature. However, only a few recent reports the incidence and clinical characteristics of patients with BFP reactions. We reviewed serological test results tested for syphilis our hospital past decade Methods This is retrospective study tertiary academic hospital. All were retrieved from laboratory database. calculated Clinical data manually. Results Among 94 462 subjects, 588 had (0.62%). Most observed...
Abstract Background and Aims This study primarily assessed the performance of UF‐1500, novel compact model fully automated urine particle analyzer evaluated its against existing UF‐5000 instrument. Materials Methods A total 648 residual specimens were randomly collected examined using both UF‐1500 instruments as well manual microscopy. For each parameter, concordance rates detection accuracy microscopy compared with UF‐5000. Results The between 75.3%–98.5%. within one group agreement...
The study objectives were to reconfirm the superiority of pulmonary valve-sparing procedure versus transannular patch for repair tetralogy Fallot and evaluate influence a right ventriculotomy in procedure.Between 1978 2003, 440 patients (aged <10 years) underwent repair. Of these patients, 242 (55.0%) procedure, 106 (24.1%) without ventriculotomy, 92 (20.9%) with ventriculotomy. End points focused on adverse events included all-cause mortality, reoperation, catheter intervention, symptomatic...
ABSTRACT Objectives We encountered the case in whom results of autoantibodies tests became transiently positive after high-dose immunoglobulin therapy and investigated effect administration these preparations on subjects with autoimmune diseases who had received therapy. Methods measured residual serum samples routine clinical testing from eight also available preparations. Results Tests for conducted before revealed a conversion anti-Sjogren’s syndrome antigen A (SS-A) antibody,...
To avoid an invasive renal biopsy, noninvasive laboratory testing for the differential diagnosis of kidney diseases is a desirable goal. As sphingolipids are demonstrated to be involved in pathogenesis various diseases, we investigated possible usefulness simultaneous measurement urinary differentiating diseases.
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<title>Abstract</title> Heart Failure (HF) is a global epidemic, with high readmission rates and significant morbidity persisting due to gaps in post-acute care. Traditional follow-up assessments often miss gradual postoperative cardiac deterioration occurring outside hospital settings. Advances remote patient monitoring (RPM) show promise, but continuous, sensitive, practical methods are lacking. Building on previous work introducing durable, soft strain sensor, this research presents...
Abstract OBJECTIVES The goal of this study was to investigate whether a larger prosthetic ring relative patient’s body surface area (BSA) is associated with an increased risk tricuspid regurgitation (TR) recurrence after annuloplasty and adverse effects on long-term outcomes. METHODS We retrospectively enrolled 239 patients who underwent mitral valve surgery between 2011 2016. index (TARI) calculated by dividing the size (mm) BSA (m2). Risk factors for recurrent TR were determined using...
To measure and validate elevated succinate in brain during circulatory arrest a piglet model of cardiopulmonary bypass.
To identify the late surgical outcomes of truncus arteriosus.Fifty consecutive patients with arteriosus who underwent surgery between 1978 and 2020 at our institute were enrolled in this retrospective, single institutional cohort study. The primary outcome was death reoperation. secondary clinical status, including exercise capacity. peak oxygen uptake measured by a ramp-like progressive test on treadmill.Nine palliative surgery, which resulted 2 deaths. Forty-eight went to repair, 17...
A patient was born with truncus arteriosus type 2, left aortic arch, anomalous origin of arch vessels, coronary artery from the right common carotid artery, and multiple extracardiac anomalies. Surgery involving translocation to truncal root, division branch pulmonary arteries ventricle-to-branch conduit placement performed at age four months. Closure ventricular septal defect using a one-way fenestrated patch upsizing successfully when reached years age.