- Dementia and Cognitive Impairment Research
- Alzheimer's disease research and treatments
- Tuberculosis Research and Epidemiology
- Spatial Neglect and Hemispheric Dysfunction
- Glycogen Storage Diseases and Myoclonus
- Neurogenesis and neuroplasticity mechanisms
- Cardiovascular Issues in Pregnancy
- Neuroendocrine Tumor Research Advances
- Ovarian cancer diagnosis and treatment
- Neurological Disease Mechanisms and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Memory and Neural Mechanisms
- Inflammatory Myopathies and Dermatomyositis
- Soft tissue tumor case studies
- Mycobacterium research and diagnosis
- Cerebrovascular and Carotid Artery Diseases
- Pregnancy-related medical research
- RNA Research and Splicing
- Ophthalmology and Eye Disorders
- Pneumocystis jirovecii pneumonia detection and treatment
- Pneumonia and Respiratory Infections
- Advanced NMR Techniques and Applications
- Bone Tumor Diagnosis and Treatments
- Preterm Birth and Chorioamnionitis
- Nuclear materials and radiation effects
Severance Hospital
2023
Yonsei University
2023
Seoul National University
2014-2017
Boramae Medical Center
2014
The University of Texas Southwestern Medical Center
2011
University of California, San Francisco
2009
Samsung Medical Center
2005-2007
Sungkyunkwan University
2005-2007
Pulmonary and Critical Care Associates
2007
Pusan National University
2007
Interstitial lung disease is a common manifestation of rheumatoid arthritis; however, little known about factors that influence its prognosis. The aim the present study was to determine whether or not usual interstitial pneumonia pattern found on high-resolution computed tomography (HRCT) prognostic significance in arthritis-associated (RA-ILD). Patients with RA-ILD were identified retrospectively (n = 82). relationship definite HRCT survival determined and compared cohort patients...
The aims of this cross-sectional study were (i) to compare the overall glucose metabolism between early onset and late Alzheimer's disease in a large sample patients; (ii) investigate pattern as function dementia severity versus disease, using statistical parametric mapping (SPM) analysis. Subjects consisted four groups: 74 patients with 46 two control groups age matched each patient group. All subjects underwent 2-[(18)F]fluoro-2-deoxy-d-glucose (FDG)-PET under same scanning conditions....
Two recently generated targeted mouse alleles of the neurogenic gene <i>Ascl1</i> were used to characterize cerebellum circuit formation. First, genetic inducible fate mapping (GIFM) with an <i>Ascl1<sup>CreER</sup></i> allele was found specifically mark all glial and neuron cell types that arise from ventricular zone (vz). Moreover, each type has a unique temporal profile marking GIFM. Of great utility, Purkinje cells (Pcs), early cohort Bergmann glia, four classes GABAergic interneurons...
Studies on the association between depression and risk of tuberculosis (TB) are lacking.To determine TB.From a nationwide database, patients with were identified to form exposure cohort 2003 2013. The control comprised an equivalent number subjects without any mood disorders, each subject age- sex-matched patient in cohort. incidence TB was A multivariable Cox proportional hazards model used estimate subsequent TB.A total 32 372 same controls identified. 2.63-fold (95%CI 1.74-3.96) higher...
<b>Objective: </b> To investigate patients with posterior cerebral artery (PCA) infarctions to learn whether hemispatial neglect is more frequent and severe after right than left PCA infarction; visual field defects (VFDs) influence the presence or severity of neglect; anatomic loci lesions that are associated neglect. <b>Methods: The authors recruited 45 infarction involved only occipital lobe plus other areas served by PCA. All subjects received seven tests within 2 months onset....
Frontotemporal dementia (FTD) often coexists with motor neuron disease (MND). To characterize glucose hypometabolism in patients FTD MND (FTD/MND), the authors compared metabolism of 8 FTD/MND that 29 FTD. All showed only frontal area, whereas most had and temporal areas. also a more symmetric pattern than
The aims of the present study were to investigate expression Toll-like receptor (TLR)2 on peripheral blood monocytes patients with nontuberculous mycobacterial (NTM) lung disease and healthy controls, assess responses these TLR2 agonists such as Mycobacterium avium lipoteichoic acid (LTA). Reverse transcriptase-PCR was used analyse mRNA in from 17 NTM 10 controls. protein secretion levels also determined for cytokines interleukin (IL)-12 p40 tumour necrosis factor (TNF)-alpha. Expression by...
Unilateral temporoparietal injury may result in an attentional deficit for stimuli presented contralesional space. Thus, bilateral degeneration associated with Alzheimer disease (AD) might a disturbance. Tests hemispatial neglect, however, primarily assess spatial asymmetries, and disorder not be detected these tests. The goal of this study was to learn whether optokinetic stimulation (OKS) would perturb the balanced deficits AD patients alter their allocation attention.In Experiment I, 10...
Dermatofibromas are slow-growing solitary nodules, composed mostly of a dermal proliferation spindle cells and epithelioid cells. Some dermatofibromas present with multinucleated giant cells, such as Touton, foreign body, osteoclast-like We report case dermatofibroma containing both Touton floret-type A 12-year-old boy presented 6-mm, firm, nontender, dusky-red to greyish nodule on his left popliteal fossa. As suggested clinically by the central opening, perforation epidermis partial...