Wenjuan Shi

ORCID: 0009-0009-0571-7768
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About
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Research Areas
  • Biopolymer Synthesis and Applications
  • Irrigation Practices and Water Management
  • Cancer Research and Treatments
  • Trace Elements in Health
  • Polymer-Based Agricultural Enhancements
  • Agronomic Practices and Intercropping Systems
  • Plant responses to water stress
  • Plant Water Relations and Carbon Dynamics
  • Plant Stress Responses and Tolerance
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Plant nutrient uptake and metabolism
  • Heavy Metal Exposure and Toxicity
  • Endoplasmic Reticulum Stress and Disease
  • Autophagy in Disease and Therapy
  • Bacteriophages and microbial interactions
  • Immune Cell Function and Interaction
  • Soil and Unsaturated Flow
  • Soil Management and Crop Yield
  • Plant Molecular Biology Research
  • Gynecological conditions and treatments
  • Advanced biosensing and bioanalysis techniques
  • Plant Virus Research Studies
  • Acute Ischemic Stroke Management
  • T-cell and B-cell Immunology
  • Nitric Oxide and Endothelin Effects

Capital Medical University
2014-2025

Xi'an University of Technology
2013-2024

PowerChina (China)
2024

Shanghai Micro Satellite Engineering Center
2024

Beijing Geriatric Hospital
2017-2024

Shanxi Medical University
2024

Anhui Science and Technology University
2023

Anhui University of Science and Technology
2023

Institute of Plant Protection
2022

Yichun University
2020-2022

Background and Purpose— Prolonged ischemia causes blood–brain barrier (BBB) damage increases the incidence of neurovasculature complications secondary to reperfusion. Therefore, targeting ischemic BBB pathogenesis is critical reducing expanding therapeutic time window tissue-type plasminogen activator (tPA) thrombolysis. This study investigates whether increasing cerebral tissue P O 2 through normobaric hyperoxia (NBO) treatment will slow progression and, thus, improve outcome delayed tPA...

10.1161/strokeaha.114.008599 article EN Stroke 2015-03-25

Damage of the blood-brain barrier (BBB) increases incidence neurovascular complications, especially for cerebral hemorrhage after tPA (tissue-type plasminogen activator) therapy. Currently, there is no effective method to evaluate extent BBB damage guide use. Herein, we investigated whether blood levels tight junction proteins could serve as biomarker damages in acute ischemic stroke (AIS) both rats and patients. We examined this reflect permeability during ischemia/reperfusion effects...

10.1161/strokeaha.117.017713 article EN Stroke 2017-09-21

Rice black-streaked dwarf virus disease (RBSDVD) and southern rice (SRBSDVD) are the most destructive viral diseases in rice. Progress is limited breeding due to lack of resistance resource inadequate knowledge on underlying functional gene. Using genome-wide association study (GWAS), linkage disequilibrium (LD) decay analyses, RNA-sequencing, genome editing, we identified a highly RBSDVD-resistant variety its first A W44 was through extensive evaluation diverse international panel....

10.1111/nph.17961 article EN New Phytologist 2022-01-11

Intracellular zinc accumulation has been shown to be associated with neuronal death after cerebral ischemia. However, the mechanism of leading in ischemia/reperfusion (I/R) is still unclear. signals are required for production proinflammatory cytokines. The present study investigated whether intracellular accumulated aggravates I/R injury through inflammatory response, and inflammation-mediated apoptosis. Male Sprague-Dawley rats were treated vehicle or chelator TPEN 15 mg/kg before a 90-min...

10.3389/fncel.2023.1065873 article EN cc-by Frontiers in Cellular Neuroscience 2023-03-08

Background and Purpose- Although intracellular zinc accumulation has been shown to contribute neuronal death after cerebral ischemia, the mechanism by which keeps on accumulating cause severe brain damage remains unclear. Herein dynamic cause-effect relationships between reactive oxygen species (ROS) production during ischemia/reperfusion are investigated. Methods- Rats were treated with chelator, ROS scavenger, mitochondria-targeted inhibitor, or NADPH oxidase inhibitor a 90-minute middle...

10.1161/strokeaha.118.021179 article EN Stroke 2018-09-01

Abstract Background Intrauterine adhesions (IUAs) are manifestations of endometrial fibrosis characterized by inflammation and fibrinogen aggregation in the extracellular matrix (ECM). The available therapeutic interventions for IUA insufficiently effective clinical setting postoperative adhesion recurrence infertility problems. In this study, we investigated whether si-SNHG5-FOXF2 can serve as a molecular mechanism inhibition ex vivo. Methods FOXF2, TGF-β1 collagen expression levels were...

10.1186/s13287-020-01990-3 article EN cc-by Stem Cell Research & Therapy 2020-11-11

Nitrosative/oxidative stress plays an important role in neuronal death following cerebral ischemia/reperfusion (I/R). Chrysophanol (CHR) has been shown to afford significant neuroprotection on ischemic stroke, however, whether its mechanism is related attenuating nitrosative/oxidative not clear. In the present study, we investigated effect of CHR injury nitric oxide (NO) production by using mouse middle artery occlusion (MCAO) model. Our results revealed that nitrite plus nitrate (NOx-) and...

10.1016/j.jphs.2018.08.002 article EN cc-by-nc-nd Journal of Pharmacological Sciences 2018-08-25

MYB-related transcription factors play important roles in plant development and response to various environmental stresses. In the present study, a novel MYB gene, designated as BnMYB2 (GenBank accession number: MF741319.1), was isolated from Boehmeria nivea using rapid amplification of cDNA ends (RACE) RT-PCR on sequence fragment ramie transcriptome. has 945 bp open reading frame encoding 314 amino acid protein that contains DNA-binding domain shares high identity with proteins other...

10.1371/journal.pone.0233375 article EN cc-by PLoS ONE 2020-05-18
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