- Gynecological conditions and treatments
- Cervical Cancer and HPV Research
- Endometriosis Research and Treatment
- Gastric Cancer Management and Outcomes
- Reproductive System and Pregnancy
- Genetics, Aging, and Longevity in Model Organisms
- Mycorrhizal Fungi and Plant Interactions
- Intellectual Property and Patents
- Reproductive tract infections research
- Gastrointestinal Tumor Research and Treatment
- Laser Applications in Dentistry and Medicine
- Virus-based gene therapy research
- Vaccine Coverage and Hesitancy
- Science, Research, and Medicine
- Retinoids in leukemia and cellular processes
- RNA Interference and Gene Delivery
- Cancer-related molecular mechanisms research
- Migration, Health and Trauma
- Pharmaceutical Economics and Policy
- CAR-T cell therapy research
- T-cell and B-cell Immunology
- Colorectal Cancer Surgical Treatments
- Biological Activity of Diterpenoids and Biflavonoids
- Immunotherapy and Immune Responses
- Gastrointestinal disorders and treatments
Hainan University
2024-2025
Southern Medical University
2006-2023
Nanfang Hospital
2019-2023
Shenzhen Maternity and Child Healthcare Hospital
2017-2023
Guangdong Academy of Medical Sciences
2020
Guangdong Provincial People's Hospital
2020
Zhujiang Hospital
2006-2020
Yan'an University
2016
Shandong University
2003
National Health Insurance Fund
2003
Abstract Background Intrauterine adhesions (IUAs) are manifestations of endometrial fibrosis characterized by inflammation and fibrinogen aggregation in the extracellular matrix (ECM). The available therapeutic interventions for IUA insufficiently effective clinical setting postoperative adhesion recurrence infertility problems. In this study, we investigated whether si-SNHG5-FOXF2 can serve as a molecular mechanism inhibition ex vivo. Methods FOXF2, TGF-β1 collagen expression levels were...
The aim of the current study was to evaluate expression microRNA (miR)-17 in endometrial tissues patients with adenomyosis (AM) and determine its biological function occurrence development disease. A total 45 fresh AM 32 normal were collected from healthy controls. miR-17 evaluated using reverse transcription-quantitative polymerase chain reaction (RT-qPCR). miR-17-targeting gene phosphatase tensin homolog (PTEN) predicted bioinformatics RT-qPCR western blot analysis. Endometrial cells...
Abstract In this study, we present MagnoliidsGDB, an integrated functional genomics database specifically developed for magnoliids, a group of plants known their unique characteristics and medicinal properties. As March 2024, MagnoliidsGDB has collected 31 genome sequences from 24 species, 149 resequencing datastes 4 842 transcriptomic datasets 20 metabolomic data 15 species. This comprehensive resource allows researchers to explore the genomic, transcriptomic, variations magnoliids. The...
There is a lack of literature comparing linear endoscopic ultrasound (EUS) and radial EUS for the prediction depth invasion in early gastric cancer (EGC). The aim this study to evaluate accuracy diagnosis submucosal (SM) compare with suspected EGC patients.Seventy-two consecutive patients who underwent preoperative assessment using or were prospectively enrolled. was categorized into mucosal SM (< T1b) deeper (≥ T1b), EUS-determined compared postoperative histopathological...
Two of the main problems stem cell and regenerative medicine are exit pluripotency differentiation to functional cells or tissues. The answer these two holds great value in clinical translation as well research. Although piling researches have revealed truth about maintenance, mechanisms underlying pluripotent self-renewal, proliferation, into specific lineages tissues yet be defined. To this end, we took full advantage a novel technology, namely, genome-scale CRISPR-Cas9 knockout (GeCKO)....
This study attempted to detect the changes of cervical cancer screening rate and willingness among female migrants, associated socio-demographic factors in Shenzhen city.Two citywide surveys were conducted using a multistage random cluster sampling method 2011 2014, respectively. Data on demographic characteristics, participation, screen collected. Logistic regression models applied possible their variations with survey years.In total, 12,017 migrants enrolled, mean age (standard deviation)...
Limited population-based studies explore the utilization and associated barriers or facilitators to cervical cancer screening in China. We attempted investigate associations of socio-demographic factors, HPV specific knowledge with testing behaviour Shenzhen, China.A citywide cross-sectional survey was conducted from January June 2015 Shenzhen city by using a multistage stratified cluster sampling method. Socio-demographic information, awareness HPV, practice testing, vaccination-related...
AIM:To construct and express ODC recombinant gene for further exploring its potential use in early diagnosis of colorectal carcinoma. METHODS:Total RNA was extracted from colon cancer tissues amplified by reverse-transcription PCR with two primers, which span the whole coding region ODC.The synthesized cDNA cloned into vector pQE-30 at restriction sites BamH I Sal constituted expression plasmid pQE30-ODC.The sequence inserted fragment confirmed DNA sequencing, fusion protein including...
Abstract Background Studies have shown that the wet suction technique in endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) generates better histological diagnostic accuracy and specimen quality than dry technique. However, conclusions of on biopsy (EUS-FNB) are still controversial. Besides, optimal number passes for EUS-FNB has not been determined. We aimed to design a large multicenter randomized trial compare versus solid pancreatic lesions (SPLs) using 22G Franseen needles...
KIR2DL1*030 differs from KIR2DL1*00302 by a single non-synonymous mutation in exon 4.
Abstract Background: Intrauterine adhesions (IUAs) are manifestations of endometrial fibrosis characterized by inflammation and fibrinogen aggregation in the extracellular matrix (ECM). The available therapeutic interventions for IUA insufficiently effective clinical setting postoperative adhesion recurrence infertility problems. In this study, we investigated si-SNHG5-FOXF2 can serve as a molecular mechanism inhibition ex vivo. Methods: FOXF2, TGF-β1 collagens expression levels were measure...
Abstract Background: Intrauterine adhesions (IUAs) are manifestations of endometrial fibrosis characterized by inflammation and fibrinogen aggregation in the extracellular matrix (ECM). The available therapeutic interventions for IUA insufficiently effective clinical setting postoperative adhesion recurrence infertility problems. In this study, we investigated whether si-SNHG5-FOXF2 can serve as a molecular mechanism inhibition ex vivo. Methods: FOXF2, TGF-β1 collagen expression levels were...