- Liver Disease Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Lymphoma Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Gastrointestinal Tumor Research and Treatment
- Chronic Lymphocytic Leukemia Research
- Diet, Metabolism, and Disease
- Neuroendocrine Tumor Research Advances
- Liver Disease and Transplantation
- Metastasis and carcinoma case studies
- Viral-associated cancers and disorders
- Traditional Chinese Medicine Studies
- Cancer-related molecular mechanisms research
- Gastrointestinal disorders and treatments
- Hepatitis B Virus Studies
- Endoplasmic Reticulum Stress and Disease
- Fatty Acid Research and Health
- Intestinal and Peritoneal Adhesions
- Cardiovascular Function and Risk Factors
- Microscopic Colitis
- Diet and metabolism studies
- Radiomics and Machine Learning in Medical Imaging
- Hepatocellular Carcinoma Treatment and Prognosis
- Trace Elements in Health
- Cancer Genomics and Diagnostics
Southern Medical University
2014-2025
Nanfang Hospital
2014-2025
First Affiliated Hospital of Guangzhou University of Chinese Medicine
2023-2025
Guangzhou University of Chinese Medicine
2023-2025
Nanjing Medical University
2023-2025
Jiangsu Province Hospital
2023-2025
Guangdong Provincial People's Hospital
2025
Second Affiliated Hospital of Nanchang University
2025
Nanchang University
2025
Guangdong Academy of Medical Sciences
2025
While there are numerous benefits to tea consumption, its long-term impact on patients with chronic kidney disease (CKD) remains unclear. Our analysis included 17,575 individuals CKD from an initial 45,019 participants in the National Health and Nutrition Examination Survey (NHANES) (1999-2018). Individuals extreme dietary habits, pregnancy, or non-CKD conditions were excluded. Key cohort demographics revealed a mean age of 62.3 years, 52.1% female participants, 57.3% identified as...
Improving the rate of polyp detection is an important measure to prevent colorectal cancer (CRC). Real-time automatic systems, through deep learning methods, can learn and perform specific endoscopic tasks previously performed by endoscopists. The purpose this study was explore whether a high-performance, real-time system could improve (PDR) in actual clinical environment.
Our hypothesis was that both the Chronic Kidney Disease-Epidemiology Collaboration (CKD-EPI) and Modification of Diet in Renal Disease (MDRD) equations would underestimate directly measured GFR (mGFR) to a similar extent people with diabetes preserved renal function.In cross-sectional study, bias (eGFR - mGFR) compared for CKD-EPI MDRD equations, after stratification mGFR levels. We also examined ability equation correctly classify subjects various CKD stages. In longitudinal study an early...
The relationship between dietary total antioxidant capacity (DTAC) and death risk among CKD populations remains unclear.Based on vitamin C equivalent (VCEAC) the component index (CDAI) indices, we analyzed two cohorts to investigate association of DTAC with all-cause CVD mortality in patients using data from National Health Nutrition Examination Survey (2007-2018). VCEAC (n = 6330) CDAI 6300) follow-up available through 2018 were included. Cox models restricted cubic splines was used model...
Angiotensin II (Ang II) has been reported to aggravate hepatic fibrosis by inducing NADPH oxidase (NOX)-dependent oxidative stress. Alamandine (ALA) protects against counteracting Ang via the MAS-related G-protein coupled (MrgD) receptor, though effects of alamandine on remain unknown. Autophagy activated reactive oxygen species (ROS) is a novel mechanism fibrosis. However, whether autophagy involved in regulation II-induced still requires investigation. We explored effect redox balance...
Conclusions regarding the suction techniques of EUS-FNB remain controversial. This study aimed to compare diagnostic accuracy dry versus wet technique in solid pancreatic lesions (SPLs) and determine optimal number passes for EUS-FNB. investigation was conducted as a multicenter, randomized, controlled, non-inferiority trial. Patients with SPLs were randomly allocated receive either or technique. The primary outcome accuracy. secondary outcomes included sensitivity, specificity, needle...
A 2-year-old boy presented with loss of appetite and recurrent cough expectoration for 1 year. Abdominal radiography performed 3 months prior revealed a circular, bead-like high-density shadow in the upper abdomen. Eleven magnetic beads were successfully extracted via gastroscopy at local hospital; however, subsequent abdominal X-ray indicated that one bead remained fixed position ([Fig. 1]).
Glycemic control is critical for managing transcatheter aortic valve replacement (TAVR) patients, especially those in intensive care units (ICUs). Emerging metrics such as the hemoglobin glycation index (HGI), stress hyperglycemia ratio (SHR), and glycemic variability (GV) offer advanced insights into glucose metabolism. However, their prognostic implications short- long-term outcomes post-TAVR remain underexplored. This retrospective cohort study analyzed 3342 ICU-admitted TAVR patients via...
Although recent guidelines recommend endoscopic resection of rectal neuroendocrine tumors (NET) ≤10 mm, there is no consensus on which modality should be performed. We aimed to compare the safety and efficacy modified cap-assisted mucosal (mEMR-C) submucosal dissection (ESD) methods for treatment NET mm.A randomized noninferiority trial comparing mEMR-C ESD was conducted. The primary outcome histological complete rate; secondary outcomes included en bloc rate, operation time, complications,...
Microbially induced peri-implant infection and dislodgement are among the most common complications of implant surgery. Most existing medical surfaces lack long-lasting antimicrobial capacity adversely affected by excessive reactive oxygen species production or burst release agents within short periods. This study aimed to perform in situ reduction anchoring silver nanoparticles (AgNPs) on polyamide (PA) pre-deposited with tannic acid (TA) coating multicycle deposition tannin-sliver (TA-Ag)...
Non-alcoholic fatty liver disease (NAFLD) with hepatic histological NAFLD activity score ≥ 4 and fibrosis stage F 2 is regarded as "at risk" non-alcoholic steatohepatitis (NASH). Based on an international consensus, NASH were renamed metabolic dysfunction-associated steatotic (MASLD) (MASH), respectively; hence, we introduced the term "high-risk MASH". Diagnostic values of seven non-invasive models, including FibroScan-aspartate transaminase (FAST), fibrosis-4 (FIB-4), aspartate to platelet...
Introduction Pre-HSCT disease control, suboptimal long-term prognosis, and a high recurrence incidence (RI) continue to pose significant challenges for hematopoietic stem cell transplantation (HSCT) in juvenile myelomonocytic leukemia (JMML) patients. Methods This retrospective cohort study assessed the effectiveness of decitabine (DAC)-based protocol JMML patients undergoing HSCT. The pre-HSCT treatment includes initial bridging treatment. efficacy DAC monotherapy versus combined with...
This study aimed to investigate the association of non-alcoholic fatty liver disease (NAFLD) and fibrosis with osteoporosis in postmenopausal women men over 50 years age type 2 diabetes (T2DM).In this study, 1243 patients T2DM (T2DM coexistent NAFLD, n = 760; no 483) were analysed. Non-invasive markers, NAFLD score (NFS) index based on four factors (FIB-4), applied evaluate risk.There was significant difference bone mineral density (BMD) between group non-NAFLD or males females after...