A5086264445- Reservoir Engineering and Simulation Methods
- Enhanced Oil Recovery Techniques
- Hydraulic Fracturing and Reservoir Analysis
- Land Use and Ecosystem Services
- Microtubule and mitosis dynamics
- Oceanographic and Atmospheric Processes
- Climate variability and models
- Advancements in Solid Oxide Fuel Cells
- Advanced Electron Microscopy Techniques and Applications
- Hydrocarbon exploration and reservoir analysis
- Cancer-related molecular mechanisms research
- Drilling and Well Engineering
- CO2 Reduction Techniques and Catalysts
- Marine and coastal ecosystems
- Rural development and sustainability
- Electronic and Structural Properties of Oxides
- Regional Economic and Spatial Analysis
- Soil Geostatistics and Mapping
- Laser-induced spectroscopy and plasma
- Machine Fault Diagnosis Techniques
- Force Microscopy Techniques and Applications
- Photosynthetic Processes and Mechanisms
- RNA and protein synthesis mechanisms
- RNA modifications and cancer
- Biochemical effects in animals
Agricultural Information Institute
2025
Chinese Academy of Agricultural Sciences
2024-2025
Peking Union Medical College Hospital
2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
Lanzhou Jiaotong University
2025
Zhejiang University
2023-2024
First Affiliated Hospital of Anhui Medical University
2023-2024
Anhui Medical University
2022-2024
Sun Yat-sen University
2024
Chinese Academy of Sciences
2005-2024
Hypertension is a primary modifiable risk factor for cardiovascular diseases, which often induces renal end-organ damage and complicates chronic kidney disease (CKD). In the present study, histological analysis of human samples revealed that hypertension induced mtDNA leakage promoted expression stimulator interferon genes (STING) in epithelial cells. We used angiotensin II (AngII)- 2K1C-treated mouse kidneys to elucidate underlying mechanisms. Abnormal packing caused by AngII...
Abstract Environmental heterogeneity is among the most important factors governing community structure. Besides widespread evidence supporting positive relationships between richness and environmental heterogeneity, negative unimodal have also been reported. However, few studies attempted to test role of on species after removing confounding effect resource availability or severity. Here we constructed an individual-based spatially explicit model incorporating a long-recognized tradeoff...
Myosins adjust their power outputs in response to mechanical loads an isoform-dependent manner, resulting ability dynamically adapt a range of motile challenges. Here, we reveal the structural basis for force-sensing based on near-atomic resolution structures one rigor and two ADP-bound states myosin-IB (myo1b) bound actin, determined by cryo-electron microscopy. The are separated 25° rotation lever. lever first ADP state is rotated toward pointed end actin filament forms previously...
The pathophysiological mechanism of acute kidney injury (AKI) is complicated, and effective drugs are still lacking. Ferroptosis a newly discovered regulatory cell death mode characterized by the lethal accumulation iron reactive oxygen species-(ROS-)-dependent lipid hydroperoxides. In recent years, ferroptosis has been confirmed to be involved in progression AKI. Paeoniflorin (PF) traditional Chinese medicine that protective effects on variety diseases including However, which PF attenuates...
Significance The dynamic behavior of microtubules, a tubular polymer, is essential for numerous processes throughout the cell. Cryoelectron microscopy (cryo-EM) has provided high-resolution snapshots microtubule during its GTP hydrolysis cycle, which regulates assembly and depolymerization. However, structural properties microtubules remain less well understood, due to limitations in cryo-EM analysis methods. Here we present method subdivide wall into elemental components refinement. This...
Rural development degree (RDD) evaluation is a very valuable guidance for rural sustainable development. Earlier studies of RDD evaluatons more focusd on establishing index system, analysing spatial–temporal evolving patterns and functional differentiations. Weighting assignment (WA) method selection vital step evaluation, but impacts different WA methods indicator weight determination were not well clarified. This study therefore employed three dominant methods, covering equal method,...
Circular RNAs (circRNAs) are special non-coding RNA (ncRNA) molecules that play a significant role in many diseases. However, the biogenesis and regulation of circRNAs diabetic nephropathy (DN) largely unknown. Here, we investigated expression profile kidney DN mice through circular sequencing (circRNA-seq). The renal biopsy samples patients with had low circ -0,000,953 expression, which was significantly associated function. Furthermore, loss-of-function gain-of-function experiments were...
Abstract Background Oxaliplatin resistance usually leads to therapeutic failure and poor prognosis in colorectal cancer (CRC), while the underlying mechanisms are not yet fully understood. Metabolic reprogramming is strongly linked drug resistance, however, role mechanism of metabolic oxaliplatin remain unclear. Here, we aim explore functions purine metabolism on oxaliplatin-induced apoptosis CRC. Methods An oxaliplatin-resistant CRC cell line was generated, untargeted metabolomics analysis...
Abstract Superhydrophobic surfaces attract increasing attention, and they have been widely studied because of their excellent anti-icing, anti-corrosion, self-cleaning, oil-water separation properties. In this study, a robust hierarchical structure was prepared on an Al-alloy substrate by spraying mixture epoxy resin (EP), hydrophobic SiO2, styrene-ethylene-butyrene-styrene (SEBS) to realize superhydrophobicity. addition, carbon dots (CDs) with fluorescence were incorporated detect...
To meet the application needs for cesium (Cs) extraction from salt-lake brines, present work explores a laser-induced breakdown spectroscopy (LIBS) method that facilitates sample analysis by near the...