James Urban

ORCID: 0009-0009-1463-5473
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About
Contact & Profiles
Research Areas
  • Glycosylation and Glycoproteins Research
  • Metabolomics and Mass Spectrometry Studies
  • Mass Spectrometry Techniques and Applications
  • Genomics and Phylogenetic Studies
  • Advanced Proteomics Techniques and Applications
  • Carbohydrate Chemistry and Synthesis
  • Proteoglycans and glycosaminoglycans research

University of Gothenburg
2023-2024

Abstract Dynamic changes in protein glycosylation impact human health and disease progression. However, current resources that capture phenotype information focus primarily on the macromolecules within central dogma of molecular biology (DNA, RNA, proteins). To gain a better understanding organisms, there is need to functional glycans biological processes. A workshop titled “Functional their curation” was held conjunction with 16th Annual International Biocuration Conference discuss ongoing...

10.1093/database/baae073 article EN cc-by Database 2024-01-01

Abstract Structural details of oligosaccharides, or glycans, often carry biological relevance, which is why they are typically elucidated using tandem mass spectrometry. Common approaches to distinguish isomers rely on diagnostic glycan fragments for annotating topologies linkages. Diagnostic only known informally among practitioners stem from individual studies, with unclear validity generalizability, causing annotation heterogeneity and hampering new analysts. Drawing a curated set 237,000...

10.1101/2024.06.28.601175 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2024-07-02

Abstract Structural details of oligosaccharides, or glycans, often carry biological relevance, which is why they are typically elucidated using tandem mass spectrometry. Common approaches to distinguish isomers rely on diagnostic glycan fragments for annotating topologies linkages. Diagnostic only known informally among practitioners stem from individual studies, with unclear validity generalizability, causing annotation heterogeneity and hampering new analysts. Drawing a curated set 237,000...

10.1007/s00216-024-05500-9 article EN cc-by Analytical and Bioanalytical Chemistry 2024-08-24
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