A5073770734- Autophagy in Disease and Therapy
- Cell death mechanisms and regulation
- Ubiquitin and proteasome pathways
- Retinoids in leukemia and cellular processes
- Calcium signaling and nucleotide metabolism
- Microbial Natural Products and Biosynthesis
- Immune cells in cancer
- Endoplasmic Reticulum Stress and Disease
- Nuclear Structure and Function
- Cellular transport and secretion
- Mitochondrial Function and Pathology
- Cancer-related Molecular Pathways
- Phytase and its Applications
- Cytokine Signaling Pathways and Interactions
- CRISPR and Genetic Engineering
- Computational Drug Discovery Methods
- Cancer Mechanisms and Therapy
- Cancer-related gene regulation
- TGF-β signaling in diseases
- Synthesis and biological activity
- PI3K/AKT/mTOR signaling in cancer
- Ion channel regulation and function
- Berberine and alkaloids research
Southwest Jiaotong University
2020-2023
Sichuan University
2021
State Key Laboratory of Biotherapy
2021
First Bethune Hospital of Jilin University
2013
Abstract Breast cancer is still one of the most common malignancies worldwide and remains a major clinical challenge. We previously reported that anthelmintic drug flubendazole induced autophagy apoptosis via upregulation eva-1 homolog A (EVA1A) in triple-negative breast (TNBC) was repurposed as novel anti-tumor agent. However, detailed underlying mechanisms remain unclear need further investigation. Here, we found impairs permeability mitochondrial outer membrane function cancer. Meanwhile,...
Objectives: Cancer is well-known as a collection of diseases uncontrolled proliferation cells caused by mutated genes which are generated external or internal factors. As the mechanisms cancer have been constantly revealed, including cell cycle, proliferation, apoptosis and so on, series new emerging anti-cancer drugs acting on each stage also developed. It worth noting that natural products one important sources for development drugs. To best our knowledge, there not any database...