A5102234458- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Early Childhood Education and Development
- China's Socioeconomic Reforms and Governance
- Social Policy and Reform Studies
- Parental Involvement in Education
- Machine Learning in Bioinformatics
- Adversarial Robustness in Machine Learning
- Brain Tumor Detection and Classification
- Radiomics and Machine Learning in Medical Imaging
- HIV Research and Treatment
- Reinforcement Learning in Robotics
- Family and Disability Support Research
- Explainable Artificial Intelligence (XAI)
- Employment and Welfare Studies
- Soybean genetics and cultivation
- Intergenerational Family Dynamics and Caregiving
- Autism Spectrum Disorder Research
- Pancreatic function and diabetes
- HIV, Drug Use, Sexual Risk
- AI in cancer detection
- Optical measurement and interference techniques
- HIV/AIDS Research and Interventions
- Forest Management and Policy
- Immunotherapy and Immune Responses
Ningbo University
2025
South China University of Technology
2025
Institute of Automation
2023-2024
Chinese Academy of Sciences
2011-2024
National University of Defense Technology
2024
Northwest A&F University
2024
Institute of Genetics and Developmental Biology
2017-2024
Shenzhen Institutes of Advanced Technology
2021-2024
North China Electric Power University
2024
Shandong Institute of Automation
2023-2024
Look After the Child Investing in children has been demonstrated to improve their lives, both during school-age years and afterward, as assessed by outcomes such employment income; furthermore, these investments often help those most need. Campbell et al. (p. 1478 ) report that can also lead improved adult health. Results from a randomized intensive intervention involved 122 four cohorts recruited 1970s suggest full-day child care for first 5 of life produced adults 30s with better metabolic...
Soybean (Glycine max [L.] Merr.) is one of the most important oil and protein crops. Ever-increasing soybean consumption necessitates improvement varieties for more efficient production. However, both correlations among different traits genetic interactions genes that affect a single trait pose challenge to breeding. To understand networks underlying phenotypic correlations, we collected 809 accessions worldwide phenotyped them two years at three locations 84 agronomic traits. Genome-wide...
Adult (age 30) educational, economic, and social-emotional adjustment outcomes were investigated for participants in the Abecedarian Project, a randomized controlled trial of early childhood education children from low-income families. Of original 111 infants enrolled (98% African American), 101 took part age 30 follow-up. Primary indicators educational level, economic status, social examined as function treatment. Treated individuals attained significantly more years education, but...
The effectiveness of two professional development interventions, each designed to strengthen teacher-child interactions in preschool classrooms, was tested using a teacher-level randomized controlled trial. Georgia's Pre-K teachers (n = 486 336 schools/centers) were randomly selected from specified regions and assigned one three conditions: 1) Making the Most Classroom Interactions (MMCI), cohort-model where small groups met for five days instruction support; 2) My Teaching Partner (MTP),...
Abstract Background To address the public health crisis of overweight and obese preschool-age children, Nutrition And Physical Activity Self Assessment for Child Care (NAP SACC) intervention was delivered by nurse child care consultants with objective improving provider parent nutrition physical activity knowledge, center-level policies practices, children’s body mass index (BMI). Methods A seven-month randomized control trial conducted in 17 licensed centers serving predominantly low income...
The discovery of a wild abortive-type (WA) cytoplasmic male sterile (CMS) line and breeding its restorer have led to the commercialization three-line hybrid rice, contributing considerably global food security. However, molecular mechanisms underlying fertility abortion restoration CMS-WA lines remain largely elusive. In this study, we cloned gene, Rf20, following genome-wide association study analysis core parent rice. We found that Rf20 was present in all parental lines, but different...
Seed size/weight plays an important role in determining crop yield, yet only few genes controlling seed size have been characterized soybean. Here, we perform a genome-wide association study and identify major quantitative trait locus (QTL), named GmSW17 (Seed Width 17), on chromosome 17 that determine soybean width/weight natural population. encodes ubiquitin-specific protease, ortholog to UBP22, belonging the protease (USPs/UBPs) family. Further functional investigations reveal interacts...
Objective Unhealthy maternal weight before pregnancy increases the risk of various adverse outcomes. We conducted a nutrition survey to provide baseline data on prepregnant nutritional status mothers in order better understand association between prepregnancy body mass index (BMI) and Design A large, prospective, population-based cohort study. Setting Data from National Free Preconception Health Examination Project (NFPHEP) China during 2010–2012. Participants 536 098 pregnant women out 2...
Vaginal products for HIV prevention that can be used on-demand before or after sex may a preferable option women with low frequency unplanned sexual activity who prefer not to use daily long-acting pre-exposure prophylaxis (PrEP). We performed dose ranging pharmacokinetics (PK) and efficacy studies of vaginally applied insert containing tenofovir alafenamide fumarate (TAF) elvitegravir (EVG) in macaques under PrEP post-exposure (PEP) modalities.
OBJECTIVE: To examine and describe coronary heart disease (CHD) mortality its pattern of change (trend) by sex, age, area residence (urban versus rural) in Tianjin, China, within the context epidemiological transition, compare it with current trends Americas Europe. METHODS: A total 104 393 cases CHD death Tianjin occurring between 1999 2008 were monitored. Death due to was coded using International Classification Diseases (ICD) standards (ninth tenth revisions). Standardized rates their...
Phosphoinositide 3-kinase (PI3K) mediates insulin actions by relaying signals from receptors (IRs) to downstream targets. The p110α catalytic subunit of class IA PI3K is the primary insulin-responsive implicated in signaling. We demonstrate here a new mode spatial regulation for PAQR3 that exclusively localized Golgi apparatus. interacts with p110α, and intracellular targeting apparatus reduced downregulation increased overexpression. Insulin-stimulated activity phosphoinositide...
Raf kinase trapping to Golgi (RKTG) is a potential tumor suppressor gene due its negative roles in regulating Ras/Raf/MEK/ERK (extracellular signal-regulated kinase) pathway and GPCR (G protein-coupled receptor) Gβγ subunit signaling. Interestingly, RKTG-deficient mice are free of tumors, although they prone form skin cancer on carcinogen administration. On the other hand, p53 well-characterized heterozygous develop sarcoma tumors starting from 12 months age. In RKTG-null mouse embryonic...
PAQR3 is a member of the progestin and adipoQ receptor (PAQR) family was recently characterized as spatial regulator that negatively modulates Ras/Raf/MEK/ERK signaling cascade. However, little known about physiological functions in tumorigenesis colorectal cancers. The function cancer development mice analyzed by crossing Paqr3-depleted with Apc Min/+ have germline mutation gene-encoding tumor suppressor adenomatous polyposis coli (APC). survival time area small intestine significantly...
Abstract Background Canine distemper virus (CDV), which is highly infectious, has caused outbreaks of varying scales in domestic and wild animals worldwide, so the development a high-efficiency vaccine broad application prospects. Currently, commercial CDV an attenuated vaccine, disadvantages complex preparation process, high cost safety risk. It necessary to develop safe effective that easy produce on large scale. In this study, sequences haemagglutinin (HA) from Yanaka strain were aligned,...