A5034203177- Venous Thromboembolism Diagnosis and Management
- Central Venous Catheters and Hemodialysis
- Structural Engineering and Vibration Analysis
- Seismic Performance and Analysis
- Blood Coagulation and Thrombosis Mechanisms
- Geotechnical Engineering and Underground Structures
- Multiple Myeloma Research and Treatments
- Renal Transplantation Outcomes and Treatments
- Chronic Lymphocytic Leukemia Research
- Advancements in Semiconductor Devices and Circuit Design
- Quantum and electron transport phenomena
- Renal Diseases and Glomerulopathies
- Monoclonal and Polyclonal Antibodies Research
- Earthquake and Tsunami Effects
- Structural Behavior of Reinforced Concrete
- Semiconductor materials and devices
- Semiconductor Quantum Structures and Devices
- BIM and Construction Integration
- Infrastructure Maintenance and Monitoring
- Acute Myeloid Leukemia Research
- Infrastructure Resilience and Vulnerability Analysis
- Complement system in diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Concrete Corrosion and Durability
- Vascular anomalies and interventions
Children's Hospital of Pittsburgh
2016-2025
University of Pittsburgh
2017-2025
University of Colorado Anschutz Medical Campus
2014-2024
Indiana Hemophilia and Thrombosis Center
2021
London North West Healthcare NHS Trust
2021
University of Colorado Denver
2010-2019
National Heart Lung and Blood Institute
2017-2019
National Institutes of Health
2017-2019
University of California, San Francisco
2018
Centers for Disease Control and Prevention
2018
Among patients younger than 21 years of age, the optimal duration anticoagulant therapy for venous thromboembolism is unknown. To test hypothesis that a 6-week provoked noninferior to conventional 3-month in age. Randomized clinical trial involving 417 age with acute, enrolled at 42 centers 5 countries from 2008-2021. The main exclusions were severe deficiencies or prior thromboembolism. Patients without persistent antiphospholipid antibodies and whose thrombi resolved not completely...
Abstract Patients receiving eculizumab have an increased risk for meningococcal disease, but most reported cases are attributable to encapsulated strains. We describe a case in which nongroupable strain, rarely causes disease healthy persons, caused fatal recipient despite vaccination.
ABSTRACT Background Management of neonatal portal vein thrombosis (PVT), a relatively common type pediatric deep thrombosis, is not completely standardized. Questions remain about the benefit anticoagulation (ATC) therapy and optimal frequency duration doppler ultrasound (US) surveillance for liver complications such as hypertension gastrointestinal bleeding. Current guidelines suggest reserving ATC only occlusive PVT, highlighting need explicit grading PVT in radiologic reports consensus...
Abstract Background Pediatric trauma patients are at high risk for development of venous thromboembolism (VTE). Our objective is to describe incidence, factors, and timing VTE, anticoagulation complications, long‐term VTE outcomes in a critically injured pediatric population. Procedure We did retrospective review (0–17 years) admissions intensive care unit from 2005 2014. center employs screening prevention protocols high‐risk based on hypercoagulable history, age, injuries, medical...
Abstract Purpose: Targeting CD79B using antibody–drug conjugates (ADC) is an effective therapeutic strategy in B-cell non-Hodgkin lymphoma (B-NHL). We investigated DCDS0780A, anti-CD79B ADC with THIOMAB technology (TDC) that consistently two anti-neoplastic molecules per antibody, contrast ADCs heterogeneous loads. Patients and Methods: This phase 1 study enrolled 60 patients histologically confirmed B-NHL had relapsed/failed to respond following ≥1 prior treatment regimens; 41 (68%) diffuse...
Key Points Nationally, 41% of kidney transplant candidates consented to receive high–Kidney Donor Profile Index (KDPI) donor offers in the United States. There was wide variation consent proportion for high-KDPI donors on basis individual characteristics and centers. Consent kidneys associated with 15% higher adjusted rates deceased transplantation. Background Despite known benefits transplantation, including transplantation from increased risk factors, many waitlisted die before lower...
The American Society of Pediatric Otolaryngology recommends pre-operative coagulation testing only when indicated by history or physical exam. Nevertheless, many surgeons test all children scheduled for tonsillectomy and/or adenoidectomy (T&A). Studies screening have had conflicting results. A decision analysis model was constructed to address the costs and health outcome states strategies in children.A 14-day Markov evaluated three strategies: (1) disorders; (2) those with a pertinent...
To create a risk model for hospital-acquired venous thromboembolism in critically ill children upon admission to an ICU.Case-control study.ICUs from eight children's hospitals throughout the United States.Critically with (cases) 0-21 years old and similar without (controls) January 2012 December 2016. Children recent cardiac surgery, asymptomatic thromboembolism, or diagnosed before ICU were excluded.None.The multi-institutional Children's Hospital-Acquired Thrombosis registry was used...
Objective: Patients and families searching the Internet about Lyme disease may find conflicting information. Our purpose was to review accuracy of information on easily available Internet. Methods: We used 15 search engines general disease. found 251 websites, which we reviewed. Of these 19 gave were analyzed. evaluated concerning 8 topics. Results: Ten websites accurate 9 provided inaccurate There with word "Lyme" in domain name, 7 sites 2 ".gov" both Conclusions: for medical encounter
Abstract: The transmission to organ transplant recipients of donor origin malignancy in the allograft has been described. Here we report malignant melanoma a renal transplanted from multiorgan donor. lung recipient presented with an lesion that was proven be and donor‐origin based on human leukocyte antigen (HLA)‐DR typing. One undergoing his second deceased transplant, having lost first graft recurrent IgA nephropathy. He unsensitized immunosuppression consisted tacrolimus, mycophenolate...
The basic components of a Persistor memory element are superconducting inductor in parallel with switch which is normally superconducting, but becomes resistive when the current exceeds critical value. When suitable pulse applied to element, persistent circulating stored. A second same direction as first makes no change, opposite reverses and produces voltage across element. By mutual inductance coupling two or more driving circuits, these elements can be made operate matrices similar those...
BackgroundA rise in hospital‐acquired venous thromboembolism (HA‐VTE) children has led to increased awareness regarding VTE prophylaxis and risk assessment. Despite no consensus exists these practices pediatrics.ObjectiveTo describe common prophylaxis, assessment models, anticoagulation dosing strategies pediatric hospitals that are members of the Children's Hospital Acquired Thrombosis (CHAT) Consortium.MethodsAn electronic survey 44 questions evaluating surrounding HA‐VTE prevention was...