Yusuke Iwata

ORCID: 0009-0009-7203-772X
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About
Contact & Profiles
Research Areas
  • Single-cell and spatial transcriptomics
  • Cardiac and Coronary Surgery Techniques
  • Cardiac Valve Diseases and Treatments
  • Xenotransplantation and immune response
  • Cell Image Analysis Techniques
  • Electrospun Nanofibers in Biomedical Applications
  • Advanced Fluorescence Microscopy Techniques
  • Tissue Engineering and Regenerative Medicine

The University of Tokyo
2024

Despite widespread adoption of tissue clearing techniques in recent years, poor access to suitable light-sheet fluorescence microscopes remains a major obstacle for biomedical end-users. Here, we present descSPIM (desktop-equipped SPIM cleared specimens), low-cost ($20,000-50,000), low-expertise (one-day installation by non-expert), yet practical do-it-yourself microscope as solution this bottleneck. Even the most fundamental configuration enables multi-color imaging whole mouse brains and...

10.1038/s41467-024-49131-1 article EN cc-by Nature Communications 2024-06-12
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