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Research Areas
- Single-cell and spatial transcriptomics
- Cardiac and Coronary Surgery Techniques
- Cardiac Valve Diseases and Treatments
- Xenotransplantation and immune response
- Cell Image Analysis Techniques
- Electrospun Nanofibers in Biomedical Applications
- Advanced Fluorescence Microscopy Techniques
- Tissue Engineering and Regenerative Medicine
The University of Tokyo
2024
Despite widespread adoption of tissue clearing techniques in recent years, poor access to suitable light-sheet fluorescence microscopes remains a major obstacle for biomedical end-users. Here, we present descSPIM (desktop-equipped SPIM cleared specimens), low-cost ($20,000-50,000), low-expertise (one-day installation by non-expert), yet practical do-it-yourself microscope as solution this bottleneck. Even the most fundamental configuration enables multi-color imaging whole mouse brains and...
10.1038/s41467-024-49131-1
article
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cc-by
Nature Communications
2024-06-12
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